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Posts by Sean Flynn

Image of a planarian, from Wiki.

Image of a planarian, from Wiki.

Do you do a PhD on Chromatin in this cool critter?

Work with @jordisolana.bsky.social @seanflynn.bsky.social, Magda Strauss and myself @lsiexeter.bsky.social on developing #singlecell #chromatin analyses to better understand pluripotency #planarians.
www.exeter.ac.uk/research/ins...

2 weeks ago 19 10 2 1

Lots of exciting PhD projects available through @swbiodtp.bsky.social

If you are interested in our project using stem cells, CRISPR and genomics, please get in touch. Informal inquiries encouraged

Project:
www.swbio.ac.uk/files/2025/1...

5 months ago 4 2 0 0

Exciting postdoc opportunity!

6 months ago 2 0 0 0
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Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

We are hiring! We are looking for a PDRA to study the epigenetics of breast cancer dormancy using chemical biology and genomics approaches. This is a 3-year position and is aimed at chemical biologists or biologists. Please share and apply using the link below 👇👇👇

www.imperial.ac.uk/jobs/search-...

7 months ago 5 5 0 0

Check it out, Chromatin Kids!

Chromatin remodeller does stuff to Transcription Factors!

Functions where it is seldom seen!

Both decreases and increases chromatin accessibility!

How cool is that?

7 months ago 54 19 3 2
Architects of the Genome: Using genomic technologies to elucidate the role of CTCF in neurodevelopmental disorders - GW4 BioMed MRC DTP Project Code MRCNMH26Ex Flynn Project Type The project is primarily wet-lab based, with a dry-lab component in Years 2 and 3. Research Theme Neuroscience and Mental Health Project Summary Download Sum...

Please share!
PhD projects available through @gw4biomeddtp.bsky.social
Please get in touch if you are interested in studying chromatin biology in stem cell models

gw4biomed.ac.uk/architects-o...

gw4biomed.ac.uk/risk-vs-prot...

gw4biomed.ac.uk/rna-dependen...

gw4biomed.ac.uk/investigatin...

7 months ago 14 6 1 1
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Giant study finds a research field that’s mostly reproducible Researchers assessed more than 1,000 results from fruit-fly immunity research published between 1959 and 2011. The majority of findings look verifiable.

Model organism communities are fantastic. Good work, "Drosophilists"! www.nature.com/articles/d41...

9 months ago 40 19 2 3
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DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers - Genome Biology Background Enhancer elements interact with target genes at a distance to modulate their expression, but the molecular details of enhancer–promoter interaction are incompletely understood. G-quadruplex...

How does (local #DNA) structure affect (3D #genome) structure? Can mutating G4s abolish #enhancers key for #blood function?

In the second part of our explorations of #G4s in gene regulation, we show how abolishing G-quadruplex structures in the genome disrupts enhancers. 1/9
doi.org/10.1186/s130...

10 months ago 15 4 1 1
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Happy to be part of this exciting work. A must-read for enhancer aficionados: A massive effort has gone into generating genome-wide STARRseq in hPSCs and conducting functional validation assays. Congratulations to all authors, Stefan and Ufuk, for leading this project 🎉.

10 months ago 27 6 0 0

Please get in touch if you want to apply for this to work with me on chromatin remodellers, enhancers and lineage commitment in mammalian stem cells at @lsiexeter.bsky.social

11 months ago 3 2 0 0

I will soon start recruiting for a Wellcome-funded postdoc position! I’ll be at the #BNA2025 meeting next week. If you like cortical development, wiring, and post-transcriptional regulation, do get in touch and we can have a chat in Liverpool! 😀

11 months ago 11 7 0 0

Job alert 🚨 We are hiring a research assistant!

This 7-year position available @exeter.ac.uk from Sept 2025 will involve keeping the lab running as well as contributing to our research activities on brain development. Full details tinyurl.com/23nyds34.

Please spread the word!

1 year ago 15 16 1 1
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We have a postdoc position in my group in collaboration with EMBL Rome; join us to make important discoveries in this exciting project.
Please apply or share.

hrwebapp.qub.ac.uk/tlive_webrec...

1 year ago 8 11 0 3
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We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today!

Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters!

allirelandchromatinconsortium.ie/annual-meeti...

1 year ago 15 13 1 3
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Award details | Funding and scholarships for students | University of Exeter

We have a funded PhD position available in Exeter @exeter.ac.uk
Gene Regulation in Brain Development and Disease 🧬
Please share / repost

www.exeter.ac.uk/study/fundin...

1 year ago 10 9 0 4
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jobs.exeter.ac.uk/hrpr_webrecr...
Interested in data management? Want a permanent position working in beautiful Devon and work collaboratively to support the work of lots of genomics team? Apply!!

1 year ago 8 6 0 1

Thread below on @robinburns.bsky.social et Al’s new paper #evobio #plantscience 🌱

1 year ago 5 0 0 0
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If you are interested in #Epigenetics apply for a PhD with Jack Hardwick and Jonathan Hanley in Bristol, and our group in Exeter.

Elucidating the role of DNA modifications in neurons
Funded by #SWBio DTP
Deadline: Dec 4
To apply: www.swbio.ac.uk/programme/ho...

1 year ago 7 5 0 1
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Nice to see all you chromatin & epigenetics aficionados here! As we build our network back up please repost details for our upcoming webinar this Friday!

We are delighted to welcome Emma Farley for her webinar 'Dependency Grammar of Developmental Enhancers' on November 22nd. Registration below 👇

1 year ago 28 10 2 3
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LSI PhD programme | Living Systems Institute | University of Exeter

Fully funded #PhD Studentship with myself and JJ Phillips at the Living Systems Institute, @uniofexeter.bsky.social

"Control of chromatin remodeller activity to direct cell fate decisions"

#Chromatin #Transcription #StemCells #StructuralBiology

Please re-skeet!

www.exeter.ac.uk/research/ins...

1 year ago 12 24 0 1

Welcome @kherka.bsky.social, who is working on chromatin and G4s

1 year ago 2 0 1 0

Exciting!

1 year ago 0 0 0 0