[ASAP] Changes to the JASMS Associate Editor Team: Farewell and Welcome Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.6c00098

(JASMS) [ASAP] Changes to the JASMS Associate Editor Team: Farewell and Welcome: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.6c00098 (RSS) #MassSpecRSS #JASMS

Meet this year’s Plenary Speakers who are shaping the conversations at #ASMS2026!

What Is Driving the Most Impactful Change in Proteomics? Industry leaders outline how advances in MS, affinity platforms, sample preparation, AI-driven analysis, and data standardization are transforming proteomics. These innovations are enabling deeper…

Technology Networks explores what’s driving major change in proteomics. Katherine Tran from SCIEX highlights how ultra‑sensitive single‑cell proteomics is reshaping discovery.
More: www.technologynetworks.com/tn/blog/what...

#DanaherNews #Proteomics #MassSpec

Scanning DIA on the ZenoTOF 8600 system enables ultra-sensitive and quantitative proteomics from single cells to post-translational modifications in a compact platform

Single cells.
No carrier.
Up to 4,700 proteins per cell.
That’s what sensitivity looks like. 🔬

www.biorxiv.org/content/10.6...

#SingleCellProteomics

Scanning DIA on the ZenoTOF 8600 system enables ultra-sensitive and quantitative proteomics from single cells to post-translational modifications in a compact platform Mass spectrometry-based proteomics increasingly demands platforms that combine quantitative rigor with the discovery capabilities of accurate mass systems. Here we present the ZenoTOF 8600 system, a compact mass spectrometry system that integrates enhanced ion capture and transmission optics with an optical detection system, Zeno trap-enhanced MS/MS, electron-activated dissociation, and scanning quadrupole data-independent acquisition (ZT Scan DIA). We show that ZT Scan DIA outperforms conventional variable-window DIA (Zeno SWATH DIA) in both identifications and quantitative reproducibility, and demonstrate the platform’s versatility across proteomics applications: thousands of protein groups from bulk samples at up to 500 samples per day, single-cell proteomics yielding up to 4,700 proteins, accurate ratio recovery in mixed-species quantitative benchmarks, low-attomole targeted quantitation, and detection of disease-relevant phosphorylation in a Parkinson’s disease cellular model using complementary CID and EAD fragmentation. The instrument’s compact footprint makes it attractive for settings where both analytical breadth and operational robustness are required.

Why choose between sensitivity and discovery?

ZenoTOF 8600 system = triple quad–class sensitivity + accurate mass QTOF.

One platform. No compromises. 🔥

Learn more: buff.ly/tvralVM

#proteomics #QTOF

Scanning DIA on the ZenoTOF 8600 system enables ultra-sensitive and quantitative proteomics from single cells to post-translational modifications in a compact platform Mass spectrometry-based proteomics increasingly demands platforms that combine quantitative rigor with the discovery capabilities of accurate mass systems. Here we present the ZenoTOF 8600 system, a compact...

Discovery.
Targeted.
PTMs.
One instrument. Many answers.

Learn more: buff.ly/tvralVM

#Proteomics #ClinicalMS

Scanning DIA on the ZenoTOF 8600 system enables ultra-sensitive and quantitative proteomics from single cells to post-translational modifications in a compact platform Mass spectrometry-based proteomics increasingly demands platforms that combine quantitative rigor with the discovery capabilities of accurate mass systems. Here we present the ZenoTOF 8600 system, a compact mass spectrometry system that integrates enhanced ion capture and transmission optics with an optical detection system, Zeno trap-enhanced MS/MS, electron-activated dissociation, and scanning quadrupole data-independent acquisition (ZT Scan DIA). We show that ZT Scan DIA outperforms conventional variable-window DIA (Zeno SWATH DIA) in both identifications and quantitative reproducibility, and demonstrate the platform’s versatility across proteomics applications: thousands of protein groups from bulk samples at up to 500 samples per day, single-cell proteomics yielding up to 4,700 proteins, accurate ratio recovery in mixed-species quantitative benchmarks, low-attomole targeted quantitation, and detection of disease-relevant phosphorylation in a Parkinson’s disease cellular model using complementary CID and EAD fragmentation. The instrument’s compact footprint makes it attractive for settings where both analytical breadth and operational robustness are required.

ZT Scan DIA > conventional DIA ✅
More IDs.
<4% protein CVs.
Better reproducibility.
Depth and precision—at the same time.

Check out the latest preprint from the Mann lab to learn more: buff.ly/tvralVM

#ZTScanDIA #ZenoTOF8600 #Proteomics

Characterizing the ZenoTOF 8600 in collaboration
@sciex.bsky.social . Scanning DIA on a compact platform — ~10K protein groups in bulk to single-cell proteomics & Parkinson's-relevant phosphosite detection with complementary CID & EAD fragmentation.
biorxiv.org/content/10.64898/2026.03.12.711261v1

Scanning DIA on the ZenoTOF 8600 system enables ultra-sensitive and quantitative proteomics from single cells to post-translational modifications in a compact platform Mass spectrometry-based proteomics increasingly demands platforms that combine quantitative rigor with the discovery capabilities of accurate mass systems. Here we present the ZenoTOF 8600 system, a compact mass spectrometry system that integrates enhanced ion capture and transmission optics with an optical detection system, Zeno trap-enhanced MS/MS, electron-activated dissociation, and scanning quadrupole data-independent acquisition (ZT Scan DIA). We show that ZT Scan DIA outperforms conventional variable-window DIA (Zeno SWATH DIA) in both identifications and quantitative reproducibility, and demonstrate the platform’s versatility across proteomics applications: thousands of protein groups from bulk samples at up to 500 samples per day, single-cell proteomics yielding up to 4,700 proteins, accurate ratio recovery in mixed-species quantitative benchmarks, low-attomole targeted quantitation, and detection of disease-relevant phosphorylation in a Parkinson’s disease cellular model using complementary CID and EAD fragmentation. The instrument’s compact footprint makes it attractive for settings where both analytical breadth and operational robustness are required.

One platform.
10× sensitivity.
Single cells → PTMs → targeted assays.

In this preprint by the Mann lab, explore how the #ZenoTOF8600 system is redefining what a single mass spec system can achieve, from deep discovery #proteomics to targeted verification and validation studies:

Help us improve your experience on sciex.com!

We’re inviting sciex.com visitors to take part in a 1‑hour interview to share how you explore our content.

Learn how you can share your voice: bit.ly/47yQ7Sm

#SCIEX #UserResearch #WebsiteExperience #DigitalStrategy #VoiceOfCustomer

At SCIEX's #USHUPO2026 Seminar, Dr Tim Heymann showed how the ZenoTOF 8600 + Evosep Eno + Aurora XS columns deliver robust, high-quality data across single-cell, global & targeted proteomics, without rebuilding workflows. Up to 4,700 proteins from a single cell with low CVs using 1400ms ZT Scan DIA.

Thank you to everyone who attended our #USHUPO2026 lunch seminar today!

What did #teammassspec members in attendance think?

SCIEX is proud to be a part of US HUPO and help drive inspiration and innovation in proteomics! Join us at booth 19, catch the latest proteomics research at Monday’s lunch seminar, and visit our posters to learn more about the ZenoTOF 8600 system.

#USHUPO #USHUPO2026

Join us for lunch at #USHUPO2026 today!

Lindsay Pino (@TalusBio) and Tim Heymann (Mann Lab) show how the #ZenoTOF8600 system powers deep discovery, targeted verification, single‑cell to global #proteomics, and #chemoproteomics with #Skyline: sciex.li/xoemx7

🕛 12:30–13:30 | 📍 Grand Ballroom AB

Tim Heymann (Mann Lab) shows how the #ZenoTOF8600 system powers deep discovery to targeted verification, plus its compatibility with Evosep Eno, IonOpticks Aurora XS, and PEAKS for end‑to‑end proteomics: sciex.li/xoemx7
🗓️ Monday | ⏰ 12:30–13:30 | 📍 Grand Ballroom AB
#USHUPO2026 #SingleCellProteomics

Looking forward to hearing how @talusbio.bsky.social is using Skyline in their latest applications.

Don’t miss Lindsay Pino’s talk at the SCIEX‑sponsored lunch seminar at #USHUPO2026! Learn how ZenoTOF 8600 data acquisition works seamlessly with #Skyline to support high‑performance, vendor‑agnostic workflows.

🕛 12:30–13:30 | 📍 Grand Ballroom AB
Register: sciex.li/xoemx7
#Proteomics

Tim Heymann shows how the #ZenoTOF8600 system powers deep discovery to targeted verification, plus its compatibility with Evosep Eno, IonOpticks Aurora XS, and PEAKS for end‑to‑end #proteomics.
sciex.li/xoemx7

🗓️ Monday | ⏰ 12:30–13:30 | 📍 Grand Ballroom AB
#USHUPO2026 #SingleCellProteomics

@lindsaykpino.com shares how chromatogram‑based #chemoproteomics using the #ZenoTOF8600 and #Skyline enables residue‑level detection of covalent binding events with depth, robustness, and throughput.

🗓️ Feb 23 | ⏰ 12:30–13:30
📍 Grand Ballroom AB, Hyatt Regency St. Louis
sciex.li/xoemx7
#USHUPO2026

Ready to push #proteomic discovery further?
Visit us at Booth 19 during #USHUPO2026 to explore our latest platforms, applications, and data‑analysis innovations. Meet the team and see how our solutions accelerate high‑impact research.

Register for our lunch seminar: sciex.li/xoemx7

#ZenoTOF8600

Register: sciex.li/xoemx7

🍽️ Join us for lunch at #USHUPO2026!
SCIEX is hosting a sponsored seminar featuring advances in high‑resolution accurate‑mass #proteomics and real‑world insights from leading experts using the ZenoTOF 8600 system.
🗓️ Feb 23 | ⏰ 12:30–13:30
📍 Grand Ballroom AB

🎟️ Register: sciex.li/xoemx7

#ZenoTOF8600

We're heading to US HUPO 2026!

Visit Booth 19 to explore our latest innovations for #proteomics. Whether you're driving translational research or biomarker discovery, we're ready to support your next breakthrough. 💪⚡

📍 St. Louis | Booth 19

#USHUPO2026 #USHUPO #ZenoTOF8600

Sialic Acid Linkage Identification in Glycosylated Peptides Using Multitandem Collision-Induced and Electronically Excited Dissociation Mass Spectrometry In our previous publication [Anal. Chem. 2023, 95, 7458–7467], we demonstrated the use of electron capture dissociation for Sa linkage analysis in N-glycans; however, its application was challenging b...

Incredible work just published yesterday using the ZenoTOF 7600
@sciex.bsky.social #Glycosylation #PTMs
pubs.acs.org/doi/10.1021/...

mRNA’s Next Act: Why Analytical Science Matters More Than Ever mRNA’s Next Act: Why Analytical Science Matters More Than Ever

SCIEX expert Kerstin Pohl shares key insights on why analytical science is essential as mRNA therapeutics evolve.

Check out her Biopharma Boardroom interview:
🔗 www.biopharmaboardroom.com/interaction/...

#mRNA #Biopharma #AnalyticalScience #DanaherNews

The BioA Collective: Your Mass Spec Bioanalysis Community This is a dedicated space for professionals, newcomers, and enthusiasts passionate about bioanalysis using mass spectrometry. Our mission is to foster a collaborative environment where members can share knowledge, discuss challenges, and explore applications of mass spectrometry in bioanalysis.

𝗛𝗮𝘃𝗲 𝘆𝗼𝘂 𝗵𝗲𝗮𝗿𝗱 𝗼𝗳 '𝗧𝗵𝗲 #𝗕𝗶𝗼𝗔𝗖𝗼𝗹𝗹𝗲𝗰𝘁𝗶𝘃𝗲'❓

It's YOUR #MassSpec Bioanalysis Community! It's a dedicated space for professionals, newcomers, and enthusiasts passionate about #bioanalysis using #MassSpectrometry to network, collaborate and connect.

Join on #LinkedIn now 👉

What Is Driving the Most Impactful Change in Proteomics? Industry leaders outline how advances in MS, affinity platforms, sample preparation, AI-driven analysis, and data standardization are transforming proteomics. These innovations are enabling deeper…

Technology Networks explores what’s driving major change in proteomics. Katherine Tran from SCIEX highlights how ultra‑sensitive single‑cell proteomics is reshaping discovery.
More: www.technologynetworks.com/tn/blog/what...

#DanaherNews #Proteomics #MassSpec

Great turnout at our SLAS 2026 lunch seminar! Attendees heard insights from SCIEX experts and customers on accelerating high‑throughput MS workflows with the Echo® MS+ AND ZenoTOF 8600 system... combined. 🤩

Thanks to everyone who joined us today! #SLAS2026

Exciting updates from #SLAS2026! The Echo® MS+ system now integrates with the ZenoTOF 8600 system, bringing enhanced sensitivity and the highest‑throughput accurate mass platform to researchers. See it live at the Danaher Life Sciences booth.