We're proud to announce Baylor College of Medicine as the first customer of our Iterative Mapping Early Access Program!

www.globenewswire.com/news-release...

Advancing next-generation proteomics with single-molecule Iterative Mapping Join our webinar on Wednesday, January 14 to explore Iterative Mapping, a cutting-edge single-molecule proteomics method. Learn how it delivers precise, quantitative analysis of proteins and proteofor...

Join us on Jan 14 at 9am PT for an exclusive webinar on Iterative Mapping, our single-molecule proteomics method for precise, AI-ready protein quantification.

🗣️Speakers - Dr. Parag Mallick, Dr. Sheri Wilcox, and Dr. Birgit Schilling

Register now:

www.selectscience.net/webinar/adva...

Sign up to receive a recording of the Nautilus HUPO 2025 Lunch Seminar Fill out the form to receive a recording of our HUPO 2025 lunch seminar.

Access the recording of our #HUPO2025 seminar to see how Professor Birgit Schilling from the @buckinstitute.org is using the Nautilus Platform to explore the tau proteoform landscape across brain regions in a mouse model of Alzheimer's disease.

nautilus-21430832.hs-sites-na2.com/download-hup...

Why is Nautilus data well-suited for AI workflows? Discover how Nautilus data is designed to provide direct and detailed measurements of single protein molecules that are well-suited for AI workflows.

Today on the Nautilus Blog - The second post in our new series focused on #AI and #proteomics. Dive in to learn how our data’s quality, simple and direct relationship to biology, and scale are designed to make it ideal for AI integration.

www.nautilus.bio/blog/why-is-...

#ML #Proteome

Earlier this week, our own Co-Founder and Chief Scientist Parag Mallick joined a panel at Fierce Biotech Week to discuss, "How Biotechs Are Leveraging AI/ML to Drive Efficiency and ROI." Three intriguing takeaways from the panel can be found in the thread below 🔽

#Proteomics #Biotech #AI

Next Thursday, October 9th at 11:15am ET, Nautilus Co-Founder and Chief Scientist Parag Mallick will join a panel at Fierce Biotech Week to discuss:

🗣️ How Biotechs Are Leveraging AI/ML to Drive Efficiency and ROI

www.fiercebiotechweek.com/event/fierce...

#ArtificialIntelligence #MachineLearning

Applications of proteomics in cancer - Round up September 2025 ~ Nautilus Biotechnology Find Nautilus' latest applications of proteomics in cancer content focusing the impact proteoform analysis can have on cancer research

In the latest update to our Proteomics and cancer eBook, you'll find content focused on the incredible ways proteoform analysis can advance cancer research.

📘 Find the eBook here:

www.nautilus.bio/blog/applica...

#Proteoforms #Proteome #Proteomics #Cancer #CancerResearch #PrecisionMedicine

Making proteoforms mainstream with the Consortium for Top-Down Proteomics

We were honored to meet with leaders in #proteoform research at #CTDP2025 last month. We are excited to work with this community to advance all #lifeSciences #research through the power of proteoforms.

Learn more:

www.nautilus.bio/blog/making-...

What are proteoforms? The patterns of modification to individual proteins create proteoforms, defined protein variants that can have drastically different functions.

📑 "What are proteoforms?" blog post:
www.nautilus.bio/blog/what-ar...

🔈 "Harnessing proteoforms to understand life's complexity" podcast:
youtu.be/detjGC4oxJA

🔈 "Are proteins a myth?" podcast:
youtu.be/3pPuxVrMxpw

🔈 "A new era in Alzheimer's research" podcast:
youtu.be/vD2QwL8eumo

Researchers are beginning to use the Nautilus Platform to do great things!

Resources covering why knowledge of #proteoforms may change how we approach diseases like Alzheimer's in thread ⬇️

#AlzheimersDisease #Proteomics

Only #proteomics could explain how the "X-gene" gives rise to all the different mutant powers in X-Men!

Life at Nautilus Interview with Nicole Newland - Senior HR Operations Generalist Discover how a drive for connection led Nicole Newland to study psychology and later translated into a fulfilling career in HR at Nautilus.

A desire to forge connections drives Nicole Newland, SHRM-CP in her role as an HR Operations Generalist at Nautilus. From recruiting to updating #HR systems and beyond, read our latest #LifeAtNautilus blog post to discover how Nicole's drive helps Nautilus grow.

www.nautilus.bio/blog/life-at...

Parag answers questions about the Nautilus Proteome Analysis Platform YouTube video by Nautilus Biotechnology

Have questions about the Nautilus Proteome Analysis Platform? Nautilus co-founder and chief scientist Parag Mallick has answers!

Find them here:

youtu.be/IUNVCNDhajk?...

#Nautilus #NautilusBiotechnology #Proteomics #NextGenerationProteomics #Proteoforms #Proteoform #Biotech #Biotechnology

Is single-molecule protein sequencing here yet? - Nature Methods As instruments and approaches emerge for single-molecule protein analysis, some developers and early users share their first impressions.

We're proud to be featured in this @natmethods.nature.com thods.nature.com article covering up-and-coming single-molecule #proteomics platforms!

www.nature.com/articles/s41...

We're developing an "entirely new measurement modality" & look forward to mapping the #proteome and #proteoform landscape.

Parag answers questions about the Nautilus Proteome Analysis Platform YouTube video by Nautilus Biotechnology

When we solicited questions about #proteomics for an episode of #TranslatingProteomics, we got many queries about the Nautilus Platform. So, we answered as many as we could in this video!

youtu.be/IUNVCNDhajk?...

#Biotech #Biotechnology #Research #ResearchAndDevelopment #Proteoforms

Translating Proteomics "Ask me anything" episode featuring special guest Don Kirkpatrick Parag Mallick, Andreas Huhmer, and special guest Don Kirk Patrick answer questions from the Translating Proteomics community.

You asked, we answered! Our latest episode of #TranslatingProteomics features answers to pressing #proteomics questions submitted by the community. Don Kirkpatrick even makes a surprise appearance to discuss how proteomics plays a powerful role in #drugDevelopment.

www.nautilus.bio/blog/transla...

Very excited for our agreement with the Allen Institute!

Download Nautilus' Poster from AAIC 2025 Fill out this form download Nautilus Biotechnology's poster form AAIC 2025.

Interested in diving into our poster from #AAIC 2025? Sign up to receive a digital copy of the poster at the link below ⤵️

nautilus-21430832.hs-sites.com/download-nau...

#Proteomics #Proteoforms #Proteome #Neuroscience

Iterative Mapping provides in-depth views of proteoform groups Discover the benefits of proteoform group analysis by Iterative Mapping.

Learn how Iterative Mapping of proteoforms on the Nautilus Proteome Analysis Platform provides uniquely actionable views of the proteoform landscape:

www.nautilus.bio/blog/iterati...

#Proteomics #Proteome #Proteoform #Proteoforms #NextGenerationProteomics #Alzheimers #AlzheimersDisease

Iterative Mapping provides in-depth views of proteoform groups Discover the benefits of proteoform group analysis by Iterative Mapping.

In our latest blog post, discover how Iterative Mapping achieves in-depth #proteoform group analysis. We walk through a theoretical example showing why the method is so unique and provide a sneak peek at data demonstrating its power.

www.nautilus.bio/blog/iterati...

#Proteomics #Biotechnology

The latest Nautilus Newsletter is huge! Read our tau proteoform preprint, dive into the preprint data in our webinar, meet with us at #AAIC2025 to learn more, and find a fascinating interview with #spatialProteoomics pioneer Fiona Ginty!

In this blog series, we walk through some of the data from our recent preprint, highlight some of the rationale for working with tau as an exemplar, and discuss some of the possibilities enabled by proteoform analysis.

I'd love to hear how you think proteoform analysis can advance your work!

Explore our new preprint featuring novel data generated on the Nautilus Proteome Analysis Platform! The preprint covers how we use Iterative Mapping to quantify tau proteoforms at the single-molecule level:

www.biorxiv.org/content/10.1...

#Proteomics #Neuroscience #Proteoforms #AlzheimersDisease

Single-molecule proteomics platform reveals biology’s hidden players Scalable single-molecule analysis could uncover low-abundance proteins and proteoforms critical for understanding complicated disease networks and therapeutic response

Discover how the Nautilus Proteome Analysis Platform is designed to enable researchers to explore the "dark proteome" in this article featuring insights from Nautilus Co-Founder and Chief Scientist Parag Mallick.

www.selectscience.net/article/sing...

Single-molecule proteomics platform reveals biology’s hidden players Scalable single-molecule analysis could uncover low-abundance proteins and proteoforms critical for understanding complicated disease networks and therapeutic response

The dark proteome is mysterious and important and we're working to bring it into the light. Learn how in this article by Cameron Smith-Craig at Select Science:

www.selectscience.net/article/sing...

#Proteomics #DarkProteome #Proteoform #Proteoforms #Biotech #Biotechnology

This is definitely one of my favorite episodes of Translating Proteomics so far. Andreas Huhmer and Sarah DeVos provide a great summary of the landscape of Alzheimer's research, biomarkers, therapeutics, and why now is such an exciting time in this space.

Webinar: Single-molecule proteome and proteoform analysis Join our webinar to discover how single-molecule proteomic analysis improves scale, sensitivity, and resolution. Learn about measuring 2,048 tau proteoforms in Alzheimer’s disease models.

Register for our upcoming webinar to discover how the Nautilus Proteome Analysis Platform enables the investigation of THOUSANDS of tau proteoforms and their roles in #AlzheimersDisease and other tauopathies.

Register here:

www.selectscience.net/webinar/brin...

#Proteomics #Neurodegeneration

How is the Nautilus Proteome Analysis Platform already being used to gain insights into Alzheimer's and other tauopathies? Attend our upcoming webinar to find out!

#Neuroscience #AlzheimersDisease #Tau #Neurodegeneration #Proteomics

Many thanks to @jtsangwrites.bsky.social for editing help and advice!

The more I read and write about proteoforms, the more I'm convinced of their importance. Measuring "protein" levels is critical, but can obscure what's happening at the functional, proteoform level as is clear in the work discussed here.

#Proteomics #Proteoforms #Cancer