Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/azohglsfiv

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/xjzfoacvhe

In 2025, C-Path proudly celebrates 20 years of impact. Take a look back at the highlights and the incredible individuals who made it all possible. Here's to the next chapter of innovation! https://f.mtr.cool/khzccxklpi

#CPath20Years #DrugDevelopment #Collaboration

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/xpjvpcxjov

Our case study showcase #bioinformatic analyses we performed for NeoPhore, in relation to their proprietary small molecule PMS2 MMR protein inhibitor!

See what we found out! 👀
www.fiosgenomics.com/pharmacological-inhibiti...

#drugdevelopment

He also hinted at a new class of synthetic antibiotics that is in current development at Roche. Hopefully there are many more new antibiotics in the future. (8/8)

#Antibiotics #DrugDiscovery #DrugDevelopment #ChemBio #Chemistry #cryoEM #AMR #Resistance #Bacteria #SAR #Synthesis #Zosurabalpin

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/nlptivkcne

With so much biological data available in the public domain, the data you need to further your #drugdiscovery and #drugdevelopment research is out there. Let us find it for you, with FG DataMine! 🔎
Learn more at www.fiosgenomics.com/service/public-databases...

#Bioinformatics in #DrugDevelopment 💊💻
In a competitive pharma landscape, advanced data analysis speeds up decisions and improves efficiency across every stage of the pipeline.

Learn how to unblock the process: www.fiosgenomics.com/unblock-the-drug-develop...
#preclinical

Our CEO, Dr. Heidi Wang, was invited to speak at Biologics World Taiwan 2026.
She shared insights on global regulatory strategy and drug development from IND to NDA.
🔗 Read more: lnkd.in/gEJci5TH
#OBIPharma #RegulatoryStrategy #DrugDevelopment #ADC #BWT2026 #BiologicsWorldTaiwan #IMAPAC

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/wgsvaezjel

Partners expand beyond initial sarcopenia program, betting that AI can help build a broader, faster pipeline for age-related diseases.

Link as first comment.

#longevity #ai #aging #drugdevelopment #sarcopenia

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/rgiintlwvn

Abivax Prices Patience for June Phase‑3 Readout Abivax says its June 2026 Phase‑3 maintenance readout could secure higher partnership terms; CEO comments were published Mar 24, 2026 (CNBC).

Abivax Prices Patience for June Phase‑3 Readout: Abivax says its June 2026 Phase‑3 maintenance readout could secure higher partnership terms; CEO comments were published Mar 24, 2026 (CNBC). 👈 Read full analysis #Abivax #Phase3 #ClinicalTrials #Biotech #DrugDevelopment

Discovery of a Colon-Targeted Prodrug As an Escherichia coli Biofilm Inhibitor for Treating Inflammatory Bowel Disease We hypothesized that the formation of biofilms contributes to the onset of inflammatory bowel disease and, thus, attempted to develop biofilm inhibitors as potential treatment options. We identified a...

Discovery of a Colon-Targeted Prodrug as an Escherichia coli Biofilm Inhibitor for Treating Inflammatory Bowel Disease

pubs.acs.org/doi/10.1021/... @pubs.acs.org

#MedicinalChemistry #DrugDiscovery #ProdrugDesign #InflammatoryBowelDisease #Pharmacology #Therapeutics #GutHealth #DrugDevelopment

Design, Synthesis, and Characterization of Prodrugs of Sulfonamide TLR4 Signaling Inhibitor TAK-242 (Resatorvid) We have previously reported two prodrug designs for the delivery of the potent TLR4 inhibitor TAK-242. Our initial design was used to covalently link TAK-242 to pancreatic islets using a linker to afford sustained delivery of the active drug after transplant. Those drug-eluting islets provided local inhibition of TLR4-linked inflammation and improved islet graft survival. Here, we describe a third family of TAK-242 prodrugs featuring two rate modulating sites, a self-immolative aniline-stabilized methylene spacer bonded directly to the sulfonamide nitrogen, an alcohol tether for bioconjugation, and a β-eliminative aryl-sulfone “trigger”. These prodrugs rapidly release TAK-242 after activation by β-elimination and a rapid subsequent 1,2-elimination, cleanly releasing the drug without detectable intermediates. This manuscript reports the preparation and characterization of a series of methylene-linked TAK-242 prodrugs, evaluating the impact of various modifications on drug release kinetics.

Design, Synthesis, and Characterization of Prodrugs of Sulfonamide TLR4 Signaling Inhibitor TAK-242 (Resatorvid) pubs.acs.org/doi/10.1021/... @pubs.acs.org

#MedicinalChemistry #DrugDesign #ProdrugStrategy #InflammationResearch #Immunology #Pharmacokinetics #Therapeutics #DrugDevelopment

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/piivrjfdyc

Follow me for a weekly read on the biotech and pharma signals that matter most. #biotech #drugdevelopment

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/tzdwlozozz

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/dyjcyazbnh

In 2025, C-Path proudly celebrates 20 years of impact. Take a look back at the highlights and the incredible individuals who made it all possible. Here's to the next chapter of innovation! https://f.mtr.cool/ghpbgeurbn

#CPath20Years #DrugDevelopment #Collaboration

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/pspmsfapzh

Panel advances bill to create state grant program to support FDA ibogaine trials for opioid treatment The committee reported House Bill 46 26 to the full Senate with a recommendation to pass; the bill would create a grant program administered by the Secretary of Health to fund public–private FDA ibogaine drug trials and requires applicants to submit an IND and seek Breakthrough Therapy designation.

A groundbreaking bill paving the way for FDA trials on ibogaine as a potential treatment for opioid use disorder just received a crucial vote from the Senate Finance Committee.

Click to read more!

#WV #CitizenPortal #DrugDevelopment #WestVirginiaHealth #PublicPrivatePartnerships

Dive into the world of #drugdevelopment w/ C-Path's #YouTube channel! Subscribe now for access to on-demand content including meetings, webinars, interviews, and more. Stay informed, stay inspired! Subscribe here: https://f.mtr.cool/ztdxblvges

Our platform, the engine behind the world’s largest in vivo CRISPR atlas, was featured in a keynote at NVIDIA GTC this week.

Read more about our collaboration here: lnkd.in/dqzmFUYH

#AI #CRISPR #DrugDevelopment #Innovation #Genomics

#KNCVMCCB2026 comes to an end with an interesting talk by Danielle Vugts. She talked about the importance of #imaging during #DrugDevelopment on the example of PET imaging of #biologics.

link.springer.com/article/10.1...
#DrugDiscovery #PETImaging #Radiolabeling #Antibodies #Nanoparticles #ChemSky

How LSD and classic psychedelics are re-entering modern psychiatry Definium's CMO talks about evaluating psychedelic medicine(s) in the modern era and developing novel treatments for mental health disorders.

The psychedelic renaissance is here. 🧠 Our latest feature explores how LSD is being rigorously researched for anxiety & depression. We spoke with Definium's Dr. Dan Karlin about the science, the stigma, and the future of mental health care. #MentalHealth #LSD #PsychedelicScience #DrugDevelopment

How LSD and classic psychedelics are re-entering modern psychiatry Definium's CMO talks about evaluating psychedelic medicine(s) in the modern era and developing novel treatments for mental health disorders.

The psychedelic renaissance is here. 🧠 Our latest feature explores how LSD is being rigorously researched for anxiety & depression. We spoke with Definium's Dr. Dan Karlin about the science, the stigma, and the future of mental health care. #MentalHealth #LSD #PsychedelicScience #DrugDevelopment

LC/MS is transforming HCP analysis in biopharma.
Hear Alphalyse, host cell protein CRO, share insights on applying LC/MS for deeper characterization, covering regulatory aspects, strategy, and performance. #lcms #proteomics #biologics #biopharma #drugdevelopment

In the U.S, the future of drug development is shifting fast thanks to NAMs, like organ-on-chip.

Watch the replay of our NAMs Live Talks: lnkd.in/gbdvkW_m

Huge thanks to our amazing guest Danny Levner from @emulatebio.bsky.social and facilitator Zaher Nahle

#NAMs #DrugDevelopment #Innovation