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Posts by Neftaly Cruz Mireles

Thanks, Nef! It was an honour to visit the University of Zurich as a postdoc-invited speaker. Great to catch up with so many people. The Botanical Garden was amazing!

1 day ago 15 2 0 0
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Thank you very much @tatsuyanobori.bsky.social for an inspiring talk at the Botanical Garden, Zurich last Friday. There is still so much to learn about plant immune responses at the single cell level! @thesainsburylab.bsky.social

#IPMB #FridayForum

1 day ago 22 3 0 1
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Join us to celebrate the 50th anniversary of the Fungal Cell and Molecular Biology Gordon Conference #GRC26

Oral presentations will be selected from abstracts. Limited places available.
GRS 👉🏽 shorturl.at/vRdwY
GRC 👉🏽 shorturl.at/pjhg0

3 weeks ago 4 1 0 0
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Magnagenes- an open science resource for the Magnaporthe research community with many new functions is being developed ⁦
@thesainsburylab.bsky.social
⁩ by Neha Sahu
#Magnafest26 #Fungal26

1 month ago 16 5 0 0

I’ll be talking today at the #Fungal26 concurrent session: AI in Fungal Research. I’ll be presenting on protein design in M. oryzae at 15:20 in the Fred Farr Forum.

I’ll also be presenting my poster (#651A) tonight - come say hi!

1 month ago 7 2 0 0

On my way to #Fungal26! I'll be speaking at #MagnaFest presenting work on regulation of Pmk1, a key component of fungal pathogenesis.

If you wanna chat I'll be at poster 652A from 7pm on the 18th. Looking forward to seeing everyone there!

@thesainsburylab.bsky.social
@genetics-gsa.bsky.social

1 month ago 9 7 1 0
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Euan Cawston on investigating the role of Mst7 and identifying potential scaffolds of the Pmk1 MAPK pathway #Magnafest26 #Fungal26 @thesainsburylab.bsky.social

1 month ago 14 4 0 0
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Here is our very own 'PhosphoJave' Bautista introducing his family of phosphorylated fungal effectors and their potential regulation #Magnafest26 #Fungal26

1 month ago 19 5 0 0
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Phosphoproteomic analysis of TOR signalling during appressorium development of Magnaporthe ⁦‪@mattwengler.bsky.social ‬⁩ #fungal26

1 month ago 33 8 1 0
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Hot off the press!

I'm thrilled to share that our paper "Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM" has been published!

Link to the paper: www.pnas.org/doi/10.1073/...

Nature is full of remarkable protein nanomachines, and now we can watch one more in action.

1 month ago 68 20 2 0
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Fungal symbioses: A multiplicity of fungi in the lichen union Increasing evidence suggests that lichens are not just a partnership between one fungus and one alga or cyanobacterium but may contain multiple intera…

New Dispatch article on the multitude of fungal symbionts now being reported in lichens, led by @puginiercamille.bsky.social

www.sciencedirect.com/science/arti...

1 month ago 36 15 1 1

Join us at the #SEBconference Florence 2026 to discuss #Plant Robustness! 🌱🔥

@kaspervangelderen.bsky.social and I are organising the P12 session "Plant robustness from molecules to ecosystems" with the support of @greenrobust.de

Check the program and submit your abstract by March 6th! 👇

1 month ago 19 15 0 0

There is a week left to apply for two available positions in my lab @ipbhalle.bsky.social

- PhD: ipb-halle.mhm.jobs/12-phd-posit...

- Postdoc: ipb-halle.mhm.jobs/13-postdocto...
Earliest start date: 01/05/2026.

We are interested in plant immune receptor biochemistry and evolution. Please share!

1 month ago 35 39 0 0

Thank you @marischuster.bsky.social for accepting our invitation and for sharing with us your exciting science. The world of proteases is fascinating!

1 month ago 9 1 1 0
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I was honored to be invited by the postdocs at the University of Zürich for a visit and a talk.
The full schedule was far too short for so much great science and Zürich in spring is just lovely.
Special thanks to @giurassicpark.bsky.social for the impeccable organization!

1 month ago 31 1 1 2

It was a pleasure to host you, @marischuster.bsky.social. Thank you for all the inspiring scientific discussions and sharing your protease fascination with us.

1 month ago 11 2 0 0
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Postdoctoral Researcher (Charpentier Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Charpentier Group at the John Innes Centre, working on cutting-edge science in the field of plant calcium signalling.

My lab at the JIC is recruiting 3 PDRA:
🔹 Bioinformatics / AI
🔹 Molecular Biology / Genetics
🔹 Proteomics
Programme funded by the Novo Nordisk Foundation.
📅 Closing date: 27 February
Apply via JIC website:
www.jic.ac.uk/vacancies/
Please share with outstanding candidates. 🙏

2 months ago 33 37 0 0

Plants use cell-surface and intracellular receptors that collaborate to detect pathogens🦠. We discovered that a key #ubiquitin recognition event recruits both receptor types into an unexpected dual receptor complex that boost the translation of defence proteins and establishes robust #PlantImmunity👇🏾

2 months ago 65 44 2 1

Fantastic opportunity to join this exciting new group led by @delaconcepcionjc.bsky.social . Cryo-ET of infection-related development in pathogenic fungi - including rice blast - an exciting, game-changing prospect. Apply below 👇

2 months ago 12 4 0 0
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PhD position in biology (m/f/d) (1/2026) Leibniz Institute of Plant Biochemistry (Halle) offers a PhD position in Biology

Please share! We are looking for a PhD student (4 years) starting from 01/05/2026 at @ipbhalle.bsky.social!
If you are interested in plant immunity, receptor biochemistry and evolution, consider applying! Deadline 09/03/2026.

Application portal: ipb-halle.mhm.jobs/10-phd-posit...

2 months ago 37 48 0 2

📢 Job alert! @delaconcepcionjc.bsky.social, junior group leader at #ZMBP, has 2 open positions (PhD and postdoc) to investigate appressoria formation in plant pathogenic #fungi using #cryoEM and #cryoET
#EmmyNoether #MPMI #plantscijob
More info 👇

2 months ago 11 9 1 0
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Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

2 months ago 83 119 0 3
Fig. 2 (shortened, full legend in paper): Structurally characterized M. oryzae effectors in complex with the HMA or HMA-like domains of host target proteins and ID-NLRs. Crystal structures of (A) AVR-PikF with the HMA-like domain of OsHIPP19 from rice (7B1I) (Maidment et al., 2021); (B) APikL2A with the HMA-like domain of sHMA25 from foxtail millet (7NLJ) (Bentham et al., 2021); (C) Pwl2 with the HMA domain of OsHIPP43 from rice (8R7D) (Zdrzałek et al., 2024); (D) AVR-PikD with the HMA-like ID of Pikp-1 from rice (5A6W) (Maqbool et al., 2015); (E) AVR-Pia with the HMA-like ID of Pikp-1 (6Q76) (Varden et al., 2019); (F) AVR1-CO39 with the HMA-like ID of RGA5 from rice (5ZNG) (Guo et al., 2018). Complexes are displayed such that the HMA/HMA-like domains are in equivalent orientations. Domains from HPP/HIPP host targets are coloured light green. Domains from ID-NLRs are coloured dark green.

Fig. 2 (shortened, full legend in paper): Structurally characterized M. oryzae effectors in complex with the HMA or HMA-like domains of host target proteins and ID-NLRs. Crystal structures of (A) AVR-PikF with the HMA-like domain of OsHIPP19 from rice (7B1I) (Maidment et al., 2021); (B) APikL2A with the HMA-like domain of sHMA25 from foxtail millet (7NLJ) (Bentham et al., 2021); (C) Pwl2 with the HMA domain of OsHIPP43 from rice (8R7D) (Zdrzałek et al., 2024); (D) AVR-PikD with the HMA-like ID of Pikp-1 from rice (5A6W) (Maqbool et al., 2015); (E) AVR-Pia with the HMA-like ID of Pikp-1 (6Q76) (Varden et al., 2019); (F) AVR1-CO39 with the HMA-like ID of RGA5 from rice (5ZNG) (Guo et al., 2018). Complexes are displayed such that the HMA/HMA-like domains are in equivalent orientations. Domains from HPP/HIPP host targets are coloured light green. Domains from ID-NLRs are coloured dark green.

⚙️🦠 REVIEW 🦠⚙️

Turley & Faulkner explore the function of plant heavy metal-associated domain-containing proteins and speculate about their functions at plasmodesmata by drawing from plant–pathogen interaction studies.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪 Christine Faulkner

2 months ago 23 18 0 0
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🗣️ 𝐼𝑛 𝑐𝑜𝑛𝑣𝑒𝑟𝑠𝑎𝑡𝑖𝑜𝑛 𝑤𝑖𝑡ℎ 𝐃𝐫. 𝐂𝐲𝐫𝐢𝐥 𝐙𝐢𝐩𝐟𝐞𝐥

Cyril Zipfel, a leading voice in plant immunity, reflects on plant immune recognition, his scientific journey, and what’s next for the field 🌱🧬

interviewed by @luisdeluna.bsky.social

👉 doi.org/10.1111/tpj.70688

2 months ago 23 11 0 3
Uppsala in late autumn

Uppsala in late autumn

Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...

2 months ago 159 185 1 5
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1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577

2 months ago 53 22 3 1

The fourth lecture of the course is now available on YouTube :) We will review how Transformers and modern LLMs work
youtu.be/vUpb6O6T2yQ

Slides
drive.google.com/file/d/1y2Vj...

For now, the English version is only available through the automatic translation of the subtitles.

2 months ago 2 1 0 0
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New lab preprint - Common and rare variant studies for the same trait identify different genes and here Diederik Laman Trip developed a protein network AI enconding to investigate if traits studied by different approaches converge on the same molecular pathways
www.biorxiv.org/content/10.6...

2 months ago 19 10 2 0
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Very greatfull to work with this brilliant and diverse bunch that make up the #proteomics team @thesainsburylab.bsky.social. #Awayday. 🇨🇦🇫🇴🏴󠁧󠁢󠁳󠁣󠁴󠁿🇬🇧🇵🇭🇬🇭🇨🇳🇨🇿🇩🇪🇳🇱

5 months ago 13 3 0 0
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Spooky season has arrived! 👻
We held our annual Pumpkin Carving Competition at @thesainsburylab.bsky.social —vote for your favourite carve! 🎃🕯️

5 months ago 19 8 8 1