NEW: HiFi now brings Hi-C to #HiFisequencing with CiFi. Traditional short-read Hi-C falls short in repetitive and low-complexity regions, but #PacBio HiFi delivers with superior accuracy and lower input needs. bit.ly/4b8k10m
#AGBT #AGBTGM
Posts by RCAC Bioinformatics @ Purdue University
With #PacBio Compatible, #HiFisequencing fits seamlessly into any lab and any omics application. Visit our suite at #AGBT in Lanai Suite 289 to explore our industry partnerships and learn how PacBio technology can elevate your research.Β #AGBT25
On top, five Andropogoneae grass species, from left to right Zea mays subsp. mays, Hemarthria uncinata, Miscanthus sinensis, Sorghum bicolor, Andropogon gerardi. On bottom, a map of the world, with collection sites of Andropogoneae grasses in points. A green background shows the distribution of Andropogoneae grasses throughout tropical and temperate latitudes
On left, a phylogeny of Andropogoneae species, with 14 independent polyploidy origins noted. On right, genome size and repeat content of each assembly. Across all assemblies, average assembly size is 1.9 Gb, and average repeat size is 1.5 Gb.
New preprint featuring my favorite maize-relatives, the Andropogoneae! We sequenced the genomes of 27 species, including lemongrass, kangaroo grass, little and big bluestem, and more -- key species that shape grasslands and prairies worldwide. www.biorxiv.org/content/10.1...
π EM Server Webinar: Protein Modeling with DiffModeler & DeepMainmast! π§¬
π
Feb 5, 2025
ποΈ Dr. Daisuke Kihara, Dr. Genki Terashi, Pranav Punuru
Topics: DiffModeler & DeepMainmast advanced cryo-EM protein modeling, DAQ tools, CryoREAD & more.
π register: kiharalab-events-5ab900351568.herokuapp.com
Apologies for the confusion! This internal event is exclusively for Purdue students, research staff, and faculty, and it requires signing in before registration.
Purdue students/staff/faculty: Join us for The Genomics Exchange, a weekly online series for bioinformatics & genomics enthusiasts! π
ποΈ First session: Friday, Jan 17, 2025
β° Time: 11:00 AM EST
π Online via Teams
Register π: forms.office.com/r/BtHXQ1tEkQ
Letβs connect & exchange ideas! π
Published: Movi: A fast and cache-efficient full-text pangenome index www.cell.com/iscience/ful... π§¬π₯οΈπ§ͺ
Sorry about that! This is an undergrad opportunity and is open to currently enrolled students. You'll need to log in through one.purdue.edu first to access the link. Let me know if you still have trouble!
What an amazing event! The team from Purdue and the Rosen Center for Advanced Computing had a packed week! We were thrilled to have had a chance to showcase all the amazing things happening on Purdueβs campus. Thanks to everyone who helped make this week special. #BOILERUP!
Congratulations to the students from Purdue Engineering on successfully presenting their capstone project! The group worked with RCAC to develop and implement an advanced, real-time predictive maintenance system using AI and IoT sensors for RCAC's #HPC infrastructure. #TheNextGiantLeap
π¨ Purdue Libraries is hiring! π¨
Looking for an undergrad to join a Gamification project this Spring! πΉοΈ
π» Skills: Unreal Engine, C++, Blueprints, GitHub
π Link to apply:
hcm-us10.hr.cloud.sap/sf/jobreq?jo...
Know someone who might be interested? Tag them! π #UnrealEngine #Gamedev #Purdue
π¨ Summer '25 Paid Internships! Join Purdueβs Anvil Research Experience for Undergraduates for hands-on experience in AI, bioinformatics, & data centers. $680/week + housing. Apply now: purdue.ca1.qualtrics.com/jfe/form/SV_... π
easySCF: A Tool for Enhancing Interoperability Between R and Python for Efficient Single-Cell Data Analysis academic.oup.com/bioinformatics/advance-a... π§¬π₯οΈπ§ͺ https://github.com/xleizi/easySCF
AlphaFold predictions on whole genomes at a glance www.biorxiv.org/content/10.1101/2024.11.... π§¬π₯οΈπ§ͺ
Promotional logo for MMseqs2 16 with the MMseqs2 Rocket mascot as a smart phone like App logo
MMseqs2 Release 16 Highlights: GPU-accelerated searchπ, ORF or new 6-frame translated search modes, contig taxonomy always keeps the longest ORF, bug fixes (reduced memory and higher sensitivity) and relicensed as MIT
π biorxiv.org/content/10.1...
πΎ mmseqs.com and πBioconda π₯οΈπ§¬π§Ά
Pylustrator offers an interactive interface to find the best way to present your data in a figure for publication. Added formatting and styling can be saved by automatically generated code. https://pylustrator.readthedocs.io/en/latest/ #python
annoy a bioinformatician with these simple phrases:
"Can't you just use Excel?"
"Isn't BLAST basically Google for DNA?"
"But did you annotate it?"
PanKB: An interactive microbial pangenome knowledgebase for research, biotechnological innovation, and knowledge mining academic.oup.com/nar/advance-article/doi/... π§¬π₯οΈπ§ͺ
Tech I'm thankful for blog.stephenturner.us/p/tech-im-th... #rstats π§¬π₯οΈπ§ͺ
"biology can remain hard longer than you can remain solvent"
AI-first biology: five years on press.airstreet.com/p/ai-first-biology-five-...
Blackbird: structural variant detection using synthetic and low-coverage long-reads www.biorxiv.org/content/10.1101/2024.11.... π§¬π₯οΈπ§ͺ https://github.com/1dayac/Blackbird
Vcfexpress: flexible, rapid user-expressions to filter and format VCFs www.biorxiv.org/content/10.1101/2024.11....
Highly accurate assembly polishing with google/DeepPolisher & PHAROAH www.biorxiv.org/content/10.1101/2024.09.... π§¬π₯οΈ https://github.com/google/deeppolisher and https://github.com/miramastoras/PHARAOH
The Wild West of spike-in normalization https://www.nature.com/articles/s41587-024-02377-y (read free: https://rdcu.be/dUiGQ π§¬π₯οΈ Code: github.com/lapatel22/spike_in_corre...
π New Helixer tutorial for gene prediction! Predict genes in complex genomes like maize with 1 commandβno repeatmasking, no extra data needed, all under 4 hrs! π½π»
Check it out: rcac-bioinformatics.readthedocs.io/en/latest/he...
#Bioinformatics #Genomics #RCAC
I created a genomics+bioinformatics starter pack. If I left you off, *please* reply and I'll add you! go.bsky.app/B5YYBfq
This week's recap highlights protein design with RoseTTAFold, surveillance with wastewater sequencing, T2T human genomes, Vitessce for visualization of multimodal spatial single-cell data, and Taxometer for taxonomic classification of metagenomics contigs... blog.stephenturner.us/p/weekly-rec... π§¬π₯οΈ