Check out the latest work from our lab! Amazing job @dadita.bsky.social 👏🏻👏🏻💯

PhDone 🥳🎓

The last few years was full of successes, failures, ups and downs, but also full of amazing people, countless talks, great conferences, incredible science and endless support from my supervisor and my thesis committee. Thanks to all people who helped me in this amazing journey! #eIF2A

Thank you! It was an incredible journey. Many thanks to all my committee members, great collaborations and amazing supervision!

Preprint by the Sendoel Lab ( @sendoellab.bsky.social ) with first author Merve Yigit ( @merveyigit.bsky.social‬ "The alternative initiation factor eIF2A regulates 40S subunit turnover in ribosome-associated quality control"
@biorxivpreprint.bsky.social‬
buff.ly/hP9Iani
‪@anupamd.bsky.social‬

#alternativetranslation #cancer #scc #ribosomequalitycontrol #ribosome #skin #usp10 #g3bp1 #rnf10 #ubiquitin #turboID #silac #massspectrometry #proteomics #riboseq #eIF2A #translation #mRNA

I’m thrilled to share my very first first-author preprint and our lab’s latest work💫 We discovered a novel role for eIF2A in ribosome-associated quality control (RQC), challenging decades-old assumptions about its enigmatic function in translation initiation.

Check it out to learn more! ⭐️
#RNA

Oh, the weather outside is frightful
But the paper submission is so delightful
And since we've no results yet
Let it pipette, let it pipette, let it pipette

How does aging alter the translational landscape of stem cells and how do these changes impact their regenerative capacity? Here we developed an in vivo single-cell ribosome profiling strategy to monitor translational landscapes of the mouse epidermis 1/6

www.biorxiv.org/content/10.1...