PandeyLab @Unibern, SWITZERLAND (@pandeylab) Bsky

Open PhD student position in laboratory of Prof. Amit V Pandey @pandeylab.bsky.social @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social @unibe.ch

2 months ago 0 1 0 0

Open PhD student position in @pandeylab.bsky.social , at @dbmr-unibe.bsky.social funded by SF Board of @medfacultyunibe.bsky.social of @unibe.ch
www.dbmr.unibe.ch/research/res...

2 months ago 1 0 0 0

How do specific enzyme defects lead to Congenital Adrenal Hyperplasia (CAH) versus isolated Disorders of Sex Development (DSD)?Our review connects the molecular dots of testicular steroidogenesis to clinical presentations, detailing the roles of StAR, CYP17A1, HSD17B3, and 5alpha-Reductase II

2 months ago 0 0 0 0

Our new book chapter, "Testicular Steroidogenesis," maps the entire journey, from fetal differentiation and "minipuberty" to complex biosynthesis pathways and the genetic basis of DSDs.

2 months ago 0 0 1 0

👶💥 "Minipuberty": The often-overlooked postnatal hormone surge crucial for male (46, X,Y) reproductive tract maturation. New publication by @pandeylab.bsky.social @dbmr-unibe.bsky.social from @unibe.ch

👉 doi.org/10.1007/978-... #Minipuberty #Hormones

2 months ago 0 2 1 0

PhD student position in laboratory of Christa E Fluck @dbmr-unibe.bsky.social @unibe.ch @medfacultyunibe.bsky.social
📢Laboratory details: lnkd.in/eND9EV-G
📄 Details: lnkd.in/eVrN-z3G
Funding: @snsf.ch
#Genetics #Endocrinology #OMICS #DSD #SexDevelopment #WES #Long-Read_Sequencing

3 months ago 1 0 0 0

🚀New Publication by @pandeylab.bsky.social @medfacultyunibe.bsky.social @dbmr-unibe.bsky.social @unibe.ch ! 🇨🇭🔬

🌿Dihydrotanshinone (DT) as a potent, selective CYP17A1 lyase inhibitor blocks androgen production 📊 #PCOS & #prostatecancer.

Cancer Research Switzerland.

📄 doi.org/10.3390/biom...

3 months ago 1 1 0 0

Can we stop androgen excess without crashing cortisol? 🤔

YES 🎯.

Dihydrotanshinone (DT), inhibits CYP17A1 lyase (androgens) not hydroxylase (cortisol).

A huge step forward for safer PCOS & CAH therapies. 🌿💊

Read more: doi.org/10.20944/pre...

#PCOS #Science #DrugDiscovery

4 months ago 0 0 0 0

New paper @pandeylab.bsky.social @dbmr-unibe.bsky.social @unibe.ch ! 🧬
Mapped functional epitopes of Human Growth Hormone for molecular "Danger Zones" in growth disorders solving paradox of "bioinactive" GH hormones. 🧵👇 [https://www.mdpi.com/1467-3045/47/12/1012] #ESKAS @novo-nordisk.bsky.social

4 months ago 0 1 0 0

Kick off Project GUITAR! 🎸🧬in Translational Hormone Research Program of @dbmr-unibe.bsky.social

Tackling Congenital Adrenal Hyperplasia by "smart" inhibitors by ✅AI-driven Design ✅ Structural Biology ✅ European collaboration (🇨🇭🇵🇱🇩🇰)🚀

#RareDisease Funding by @medfacultyunibe.bsky.social @unibe.ch

4 months ago 1 0 0 0

🔬
@pandeylab.bsky.social , @unibe.ch
study in #JCEM @endosocjournals.bsky.social
novel POR G88S mutation causing severe #PORD. 🧬

Beyond the disorder, this mutation creates a critical pharmacogenomic risk 💊⚠️

gene-to-clinic story: doi.org/10.1210/clin...

#Endocrinology #RareDisease

5 months ago 1 0 0 0

Great collaboration with Dr. Louise Kjærulff Prof. Dan Staerk Prof. Birger Lindberg Møller Prof. Flemming Steen Jørgensen from Dept. of Drug Design and Pharmacology (ILF), University of Copenhagen, Therina du Toit in Bern

5 months ago 1 0 0 0

Congratulations to PhD student Jubira Yakubu from @pandeylab.bsky.social of @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social @unibe.ch for winning the Best Presentation Award at the Annual Research Conference of Children's Hospital. Big thank you to Cancer Research Switzerland for funding.

5 months ago 0 1 1 0

PhD Student in Molecular and Translational Medicine: Dissecting & Targeting a Human Metabolic Disorder funded by @snsf.ch in @pandeylab.bsky.social @unibe.ch @medfacultyunibe.bsky.social @dbmr-unibe.bsky.social

6 months ago 0 2 0 0

Postdoctoral Research Position on modulation of human steroid and drug metabolism by redox proteins like P450 oxidoreductase (POR), Ferredoxin reductase (FDXR), ferredoxin (FDX1). funded by @snsf.ch in @pandeylab.bsky.social at @unibe.ch @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social

6 months ago 1 4 0 0

Postdoctoral Research Position on modulation of human steroid and drug metabolism by redox proteins like P450 oxidoreductase (POR), Ferredoxin reductase (FDXR), ferredoxin (FDX1). funded by @snsf.ch in @pandeylab.bsky.social at @unibe.ch @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social

6 months ago 1 4 0 0

PhD Student in Molecular and Translational Medicine: Dissecting & Targeting a Human Metabolic Disorder funded by @snsf.ch in @pandeylab.bsky.social @unibe.ch @medfacultyunibe.bsky.social @dbmr-unibe.bsky.social

6 months ago 0 2 0 0

📣 Check out the Program for 24th ICCP450 meeting 📣
lnkd.in/eei79-2y
www.ICCP450Bern.Unibe.ch
Leading experts in #P450 research from across the world are gathering in beautiful Bern from 30th June to 4th July 2025!!

10 months ago 0 0 0 0

24th International Conference on Cytochrome P450

24th ICCP450 meeting June to 4th July 2025 30 at @unibe.ch is being generously supported by a grant to @pandeylab.bsky.social by 🙏
@snsf.ch #SNSF #Switzerland. 🌍Join us in Bern. Register: iccp450bern.unibe.ch #Science #Heme #CytochromeP450 #P450

11 months ago 3 1 0 0

Nanoparticles with curcumin and piperine modulate steroid biosynthesis in prostate cancer - Scientific Reports Scientific Reports - Nanoparticles with curcumin and piperine modulate steroid biosynthesis in prostate cancer

Latest paper in @springernature.com by Jibira Yakubu
@pandeylab.bsky.social shows curcumin + piperine nanoparticles (CPN) inhibit steroid production in prostate cancer cells! #ProstateCancer #Nanomedicine #Curcumin

Read: doi.org/10.1038/s415...

@unibe.ch Funded by Cancer Research Switzerland

11 months ago 3 0 0 0

🐻 Get ready, #P450 peeps! for guru David (aka @p450nelson.bsky.social )! #ICCP450! 🎉 He literally wrote the book (well, the website!) on P450 nomenclature 🧬 – foundational work on drug metabolism, toxicology genomics! 🗓️ #P450 #CytochromeP450 #DrugMetabolism #Pharmacology 🔬 www.iccp450bern.unibe.ch

1 year ago 0 0 0 0