#allostery in a #P450 enzyme investigated by variable temperature crystallography and md simulations…. pubs.rsc.org/en/content/a...
A color photo of a length of residential street in which the asphalt was laid pretty straight but the double center line is anything but.
Alright road crew, never drink while driving a paint striping truck.
📷 Pentax K-70
🔘 Pentax 55-300mm APS-C
#Photography #Art #Suburban #Suburb #VanishingPoint #Street #Road #Asphalt #Residential #EastCoastKin #BlueSkyArtShow #StreetPhotography #PhotographersOfBlueSky #PhotoOfTheDay #Pentax #P450
Latest work for researchers in #CH bond activation using an engineered #P450 #enzyme #biocatalyst. Excellent work from all.
Great resource!
Exploring #P450 superfamily diversity with P450Atlas - Online tool for automated subfamily assignment
onlinelibrary.wiley.com/doi/full/10....
Fantastic work by the Ward lab to repurpose cytochrome #P450 enzymes for a new-to-nature asymmetric metal-catalysed H atom transfer! Just released
@Nature
: doi.org/10.1038/s415.... A must read!🧪
📣 Check out the Program for 24th ICCP450 meeting 📣
lnkd.in/eei79-2y
www.ICCP450Bern.Unibe.ch
Leading experts in #P450 research from across the world are gathering in beautiful Bern from 30th June to 4th July 2025!!
New paper investigating a new #biocatalyst from a #metagenome
Characterisation of the #thermophilic #P450 CYP116B305 identified using metagenomics-derived sequence data from an Australian hot spring. Appl Microbiol Biotechnol 109, 133 (2025). doi.org/10.1007/s002...
24th ICCP450 meeting June to 4th July 2025 30 at @unibe.ch is being generously supported by a grant to @pandeylab.bsky.social by 🙏
@snsf.ch #SNSF #Switzerland. 🌍Join us in Bern. Register: iccp450bern.unibe.ch #Science #Heme #CytochromeP450 #P450
New paper in chemical science on #p450 #sterol oxidation.
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
Gene fusion and functional diversification of #P450 genes facilitate thermophilic fungal adaptation to temperature change
doi.org/10.1080/2150...
@tandfresearch.bsky.social
A pretty protein structure made mostly of beta-sheets. There are two hemes, one per monomer. In P460, the heme is linked to a lysine residue and can do hydroxylamine oxidation. In one c prime beta, the heme has peroxidase-like activity. In another,it does gas binding.
I'm particularly interested in how these properties in cytochromes P460 are affected by the unusual heme-protein crosslinking. This makes them green, distorts the heme and allows them to oxidise the iron-bound NH2OH to N2O, a greenhouse gas. This is basically what makes them #P460 instead of #P450!
🐻 Get ready, #P450 peeps! for guru David (aka @p450nelson.bsky.social )! #ICCP450! 🎉 He literally wrote the book (well, the website!) on P450 nomenclature 🧬 – foundational work on drug metabolism, toxicology genomics! 🗓️ #P450 #CytochromeP450 #DrugMetabolism #Pharmacology 🔬 www.iccp450bern.unibe.ch
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.
Check out 24th International Conference on Cytochrome P450 #ICCP450 to present your #P450 #Research:
www.iccp450bern.unibe.ch
organized by @pandeylab.bsky.social of @unibern.bsky.social
Leading #P450 researchers from across the world will present their latest work at this meeting.