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Posts by Kelly Nguyen

Three-year funded postdoctoral fellowship for scientists returning after a 12-month career break, deadline May 17, 2026.

Three-year funded postdoctoral fellowship for scientists returning after a 12-month career break, deadline May 17, 2026.

The LMB is proud to launch the Career Returner Fellowship, a three-year, fully funded postdoc placement for scientists who have had a career break of over 1 year.

Applications are open now!

More details: mrclmb.ac.uk/careers-and-...

Please share this post with anyone who may be interested!

6 days ago 15 17 0 2

Congratulations Helen on the well-deserved honour!

1 week ago 1 0 1 0
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I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

1 week ago 125 62 3 7
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Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

2nd call for postdoc positions in the lab. Get in touch for more information or simply apply here: mbg.au.dk/en/news-and-...

1 week ago 11 13 0 0
Dear colleagues,
With deep sadness I share the news that Andreas Engel passed away last Wednesday, at the age of 82, after a courageous fight against an aggressive caner. Only half a year ago, he was out hiking in the Italian mountains with his wife Barbara, walking 160 km in a single week. 
Andreas trained as a physicist in Bern, Switzerland, before heading to John Hopkins University in Baltimore for his postdoctoral work. He then led a research group at the Biozentrum in Basel, and in 1985 took on the role of a group leader in research and development at Ilford Ltd. in Fribourg, Switzerland.
In 1987, he joined forces with his colleague Ueli Aebi to establish the Maurice E. Müller Institute at the Biozentrum of the University of Basel. Together, Ueli and Andreas served as professors for structural biology there for almost a quarter century, leaving a lasting mark on the field of structural biology as we know it today.
 
Andreas Engel was a true pioneer. He was among the first to apply atomic force microscopy (AFM) with the tip operating under water, and one of the earliest researchers to perform 3D reconstructions using scanning transmission electron microscopy, achieving remarkable high-resolution maps of porin 2D crystals by STEM. He became a leading expert in membrane protein 2D crystallization, and his group played a key role in the determination of the first aquaporin structure, in collaboration with Peter Agre and Yoshinori Fujiyoshi. 
As he approached retirement from Basel, Andreas founded the Center for Cellular Imaging and NanoAnalytics (C-CINA) of the University of Basel, which in 2009 operated among others one of the very early Titan Krios instruments. From 2008 also held a professorship at Case Western Reserve University, Cleveland, followed by a position at TU Delft in the Netherlands in 2013. In 2020, he was among the founding members of CryoWrite, a company in Basel that he led as CEO until recently. 
His contributions to science, to the tools of str…

Dear colleagues, With deep sadness I share the news that Andreas Engel passed away last Wednesday, at the age of 82, after a courageous fight against an aggressive caner. Only half a year ago, he was out hiking in the Italian mountains with his wife Barbara, walking 160 km in a single week. Andreas trained as a physicist in Bern, Switzerland, before heading to John Hopkins University in Baltimore for his postdoctoral work. He then led a research group at the Biozentrum in Basel, and in 1985 took on the role of a group leader in research and development at Ilford Ltd. in Fribourg, Switzerland. In 1987, he joined forces with his colleague Ueli Aebi to establish the Maurice E. Müller Institute at the Biozentrum of the University of Basel. Together, Ueli and Andreas served as professors for structural biology there for almost a quarter century, leaving a lasting mark on the field of structural biology as we know it today. Andreas Engel was a true pioneer. He was among the first to apply atomic force microscopy (AFM) with the tip operating under water, and one of the earliest researchers to perform 3D reconstructions using scanning transmission electron microscopy, achieving remarkable high-resolution maps of porin 2D crystals by STEM. He became a leading expert in membrane protein 2D crystallization, and his group played a key role in the determination of the first aquaporin structure, in collaboration with Peter Agre and Yoshinori Fujiyoshi. As he approached retirement from Basel, Andreas founded the Center for Cellular Imaging and NanoAnalytics (C-CINA) of the University of Basel, which in 2009 operated among others one of the very early Titan Krios instruments. From 2008 also held a professorship at Case Western Reserve University, Cleveland, followed by a position at TU Delft in the Netherlands in 2013. In 2020, he was among the founding members of CryoWrite, a company in Basel that he led as CEO until recently. His contributions to science, to the tools of str…

Photo of Andreas Engel

Photo of Andreas Engel

Sad news on the passing of Prof. Andreas Engel, a pioneer in the field of cryo-EM (shared with the 3DEM community by Henning Stahlberg).
Andreas' kindness, warmth, and enthusiasm for science and his colleagues will be missed.

2 weeks ago 55 26 0 2

Our latest @biorxivpreprint.bsky.social: "Prion-like transmission of human tau strains in the mouse brain" 🥳

With Michel Goedert and Masato Hasegawa.

www.biorxiv.org/content/10.6...

2 weeks ago 35 19 1 0
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Postdoctoral Scientist | PNAC | Dr Ana Tufegdzic Vidakovic | LMB 2142 - Cambridge, Cambridgeshire (GB) job with MRC Laboratory of Molecular Biology (LMB) | 12857096 Postdoctoral Scientist Salary £42,694 per annum pro rata Fixed term for 3 years MRC Laboratory of Molecular Biology, Cambridge, UK Applications are...

We are looking for a postdoc to join us on the quest for understanding RNA Pol II destruction machines! If you are curious why more than 80% of Pol II are removed from genes, check out the post below:

www.nature.com/naturecareer...

2 weeks ago 11 12 0 2

New preprint! We identified many components that localize to the structure involved in "eating" in a marine organism.
#ProtistOnSky #diplonemid
www.biorxiv.org/content/10.6...

2 weeks ago 33 16 1 0
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Inaugural paper from the Lau lab. Beautiful work. Congratulations Clinton and teams!

3 weeks ago 6 1 0 0

Check out the final version of this work, out today! @natcomms.nature.com www.nature.com/articles/s41...

3 weeks ago 38 21 5 0

Funny it looks very similar to the tri-snRNP :D.

3 weeks ago 0 0 0 0

Thank you so much. I hope Jack likes it :).

3 weeks ago 1 0 0 0

Thank you so much Yiliang! We should catch up soon.

3 weeks ago 1 0 0 0

Thank you so much Zoe!

3 weeks ago 0 0 0 0

Congratulations Verena, now in our neighboring Carter lab!

3 weeks ago 2 0 0 0
Depictions of the structure of CDK11-cyclin L-SAP30BP. Four cryo-EM densities are shown at the top, two molecules models at the bottom. CDK11 is green, cyclin L is purple, and SAP30BP is yellow.

Depictions of the structure of CDK11-cyclin L-SAP30BP. Four cryo-EM densities are shown at the top, two molecules models at the bottom. CDK11 is green, cyclin L is purple, and SAP30BP is yellow.

Have a look at our latest results on #CDK regulation, just posted as a pre-print! This study was spearheaded by PhD student Amy McGeoch. Amy has determined the #cryoEM structure of the CDK11-cyclin L-SAP30B complex, an important regulator of #spliceosome activation.
www.biorxiv.org/content/10.6...

3 weeks ago 65 24 1 1

Excited to share my postdoc work on the cryo‑EM structure of the budding yeast telomerase holoenzyme! 🧫🧬
It’s been a real privilege to be part of the awesome Kelly Lab @kellythd-nguyen.bsky.social. Grateful as well to the incredible facilities @mrclmb.ac.uk.

3 weeks ago 46 10 3 1
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Bittersweet moment to give special thanks to the late Kiyoshi Nagai and former colleague for developing the yeast expression system that we made use of in this work.

3 weeks ago 21 4 1 0

Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍.
www.science.org/doi/10.1126/...
www.youtube.com/watch?v=gFE4...

3 weeks ago 203 74 9 2
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Excited to decode the intricate language of ubiquitin chains and unravel their role in protein degradation? 🧬🔬
👉 APPLY NOW to join the lab of Dr. Leo Kiss @leokiss.bsky.social @imprs-lm.bsky.social.
#CellularBiochemistry #Ubiquitin #Proteostasis #ProteinDegradation

4 weeks ago 20 15 0 1

Happy to share my first adventure in #TeamTomo in collaboration with the talented @inaharasimov.bsky.social. It was a fun experience experience with a lot of learning along the way.

4 weeks ago 42 12 1 0
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PlantScience.ai: An LLM-Powered Virtual Scientist for Plant Science PlantScience.ai is a virtual plant scientist that combines a continuously expanding knowledge graph with large language models to provide citation-traceable, expert-level answers across plant biology....

Our paper is now live🎉! Huge thanks to all co-authors for your support @yiliangding.bsky.social @johninnescentre.bsky.social @thesainsburylab.bsky.social Our journey of AI in plant science starts here, built for plant scientists, aimed at accelerating discovery.
www.cell.com/molecular-pl...

4 weeks ago 6 3 0 0
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🔍 Want to uncover how proteolytic enzymes in the ubiquitin system work—and exploit those insights for novel therapeutic approaches? Apply to the Gersch Lab @maltegersch.bsky.social at @imprs-lm.bsky.social.
#proteolysis #ubiquitin #biochemistry #proteinchemistry

1 month ago 8 7 0 0
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📣 Physicists and engineers: apply your experimental skills to biology! Join the group of Katerina Naydenova @imprs-lm.bsky.social for a #PhD to develop new technologies that enable answering fundamental biological questions. Apply NOW!

1 month ago 10 11 0 1
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Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

4 weeks ago 190 77 6 9

Happy to share our latest work on the previously uncharacterized splicing factor Cwc15! Importantly, all of the people who did this work are/were undergrads!

S. cerevisiae Cwc15p Tunes the Spliceosome Active Site for 5' Splice Site Cleavage

www.biorxiv.org/content/10.6...

4 weeks ago 21 6 1 0
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Thalia’s Team fundraising for OSCAR's Paediatric Brain Tumour Charity Help Chris Toseland raise money to support OSCAR's Paediatric Brain Tumour Charity

Three years ago Thalia was diagnosed with a brain tumour. She had multiple surgeries, chemotherapy and radiotherapy.

This year we are walking the Nine Edges Challenge to raise awareness and money for OSCAR's Paediatric Brain Tumour Charity.

Please donate: www.justgiving.com/team/thaliaf...

1 month ago 9 6 0 1

Always excited when Relion changes its color 😍.

1 month ago 9 0 0 0
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Training a force field for proteins and small molecules from scratch Force fields for molecular dynamics are usually developed manually, limiting their transferability and making systematic exploration of functional forms challenging. We developed a graph neural networ...

Check out our pre-print, where we train a protein and small molecule force field from scratch with a graph neural network.

We show comparable performance to existing, manually-tuned force fields on a range of tasks including binding free energy prediction. (1/4)

arxiv.org/abs/2603.16770

1 month ago 35 13 1 1
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Join #EMBOCryoEM to get a comprehensive foundation in advanced single-particle and cellular tomography techniques – we'll cover the entire workflow from sample preparation to data collection and image processing.

https://s.embl.org/cry26-01-bl
Apply by: 11 May 2026
@embo.org

1 month ago 22 16 0 1