The peer reviewed version is out. Our study suggests this process is not limited to a single dimer architecture: we identified an additional dimeric arrangement, pointing to greater structural diversity in stress-induced ribosome hibernation-like states. doi.org/10.1093/nar/...
En route to share our latest work on the conformational landscape of opioid receptor activation. Grateful to my friend and collaborator, Dr. Susruta Majumdar, for the invitation—looking forward to connecting with everyone at WashU @washumedicine.bsky.social!
Black-and-white historical photograph of renowned Chinese-American physicist Dr. Chien-Shiung Wu. She stands confidently in a white lab coat, facing the camera with a calm, poised expression and direct gaze. Her dark hair is elegantly styled. Behind her is a large, complex rack of mid-20th-century electronic equipment, including tangled cables, multiple control panels, dials, switches, and connectors. Prominently visible is a device labeled "CU1721" (a linear amplifier), with additional markings such as "GUIDANCE CONTROL," "FOR AC ANALYSIS," "TIME CONTROL," input/output ports, and other technical labels typical of nuclear physics instrumentation from that era. The setting captures the intensity and precision of experimental nuclear research in the post-WWII period.
Physicist Chien-Shiung Wu died #OTD in 1997.
She conducted the Wu experiment (proving parity isn't conserved) for which her male colleagues won the 1957 Nobel Prize in Physics. Her role wasn't publicly honored until she was awarded the inaugural Wolf Prize in 1978. #WomenInSTEM #MatildaEffect
We’re hiring! Our group at CSHL has openings for postdoctoral fellows in structural biology with a focus on ion channels and receptors in neurotransmission and cancer immunology. Join and pursue unique, cross-disciplinary science to boost your career. jobrxiv.org/job/cold-spr...
Dear colleagues, With deep sadness I share the news that Andreas Engel passed away last Wednesday, at the age of 82, after a courageous fight against an aggressive caner. Only half a year ago, he was out hiking in the Italian mountains with his wife Barbara, walking 160 km in a single week. Andreas trained as a physicist in Bern, Switzerland, before heading to John Hopkins University in Baltimore for his postdoctoral work. He then led a research group at the Biozentrum in Basel, and in 1985 took on the role of a group leader in research and development at Ilford Ltd. in Fribourg, Switzerland. In 1987, he joined forces with his colleague Ueli Aebi to establish the Maurice E. Müller Institute at the Biozentrum of the University of Basel. Together, Ueli and Andreas served as professors for structural biology there for almost a quarter century, leaving a lasting mark on the field of structural biology as we know it today. Andreas Engel was a true pioneer. He was among the first to apply atomic force microscopy (AFM) with the tip operating under water, and one of the earliest researchers to perform 3D reconstructions using scanning transmission electron microscopy, achieving remarkable high-resolution maps of porin 2D crystals by STEM. He became a leading expert in membrane protein 2D crystallization, and his group played a key role in the determination of the first aquaporin structure, in collaboration with Peter Agre and Yoshinori Fujiyoshi. As he approached retirement from Basel, Andreas founded the Center for Cellular Imaging and NanoAnalytics (C-CINA) of the University of Basel, which in 2009 operated among others one of the very early Titan Krios instruments. From 2008 also held a professorship at Case Western Reserve University, Cleveland, followed by a position at TU Delft in the Netherlands in 2013. In 2020, he was among the founding members of CryoWrite, a company in Basel that he led as CEO until recently. His contributions to science, to the tools of str…
Photo of Andreas Engel
Sad news on the passing of Prof. Andreas Engel, a pioneer in the field of cryo-EM (shared with the 3DEM community by Henning Stahlberg).
Andreas' kindness, warmth, and enthusiasm for science and his colleagues will be missed.
I’m excited to share new work out of the lab at @NYULangone led by @kenjifujihara.bsky.social ! We took a first principles approach to evaluating @ferroptosis induction for cancer therapy via targeting the SLC7A11-glutathione-GPX4 axis. www.biorxiv.org/cgi/content/...
Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.
Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme?
Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues.
Apply by 16 MAR
www.nature.com/naturecareer...
A photo of Lynmarie Thompson, the current president of the Biophysical Society, presenting plaques to Ilya Levental and Ariane Briegel, the Program Chairs of the 2026 Annual BPS Meeting
Thank you Lynmarie Thompson, @leventallab.bsky.social and
@arianebriegel.bsky.social for your service to the @biophysicalsoc.bsky.social and in organizing the 2026 BPS Meeting!
We often get questions about the ins-and-outs of Presubmission Enquiries when engaging with scientists. Are they important? Will they help my paper get sent for review? Can they benefit me? If you're curious as well, please check out our editorial in the Feb issue!
Our study of the CAT1 amino acid transporter and viral receptor is now online in @natcomms.nature.com!
Spearheaded by the incredibly talented @mingda-ye.bsky.social with colleagues from @cmd.ox.ac.uk, Strubi, CAMS Oxford Institute, @ndm.ox.ac.uk, and supported by the IM2PACT consortium.
Before you leave for San Francisco, plan your time at #bps2026 using the BPS Events App!
Available on the App Store and Google Play buff.ly/8ykSJEK
Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳
mrc.tal.net/vx/mobile-0/...
Plan your time at #bps2026 using the BPS Events App -- Available on the App Store and Google Play www.biophysics.org/2026meeting/...
We are hiring for group leaders again — EBI is a great place to start your research group!
embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
Jane changed how I both think about and teach biochemistry.
@jesseduquette.bsky.social
🚨Postdoc opportunity🚨Our lab at MRC-LMB Cambridge is recruting a postdoc to study transcription-coupled splicing using cryoEM and endogenous isolation! 🔬 🧬
Please feel free to get in touch directly #postdoc #cryoEM #biochemistry #splicing
Apply here by 11 Feb
www.nature.com/naturecareer...
Lead a lab at Janelia Pioneer next-generation tools for biological discovery Apply by Feb. 3, 2026 janelia.org/groupleader
Apply by Feb. 3 to become a Janelia Group Leader!
Group Leaders drive breakthroughs & experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, & methods that don't yet exist. Learn more: janelia.org/groupleader 🧪
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
SGP congratulates the first recipients of the new Rising Star Travel Awards! The application deadline for the next round of awards has been extended to 31 January 2026. See sgpweb.org/awards/risin... for more info.
It was great fun collaborating with the groups of Ruben, Joe, Emad, David, John and Chris. To understand the mechanism of secondary membrane transporters, structures and kinetics are only a starting point; studies by smFRET and MD will provide info on the dynamics and energetics — a molecular movie!
A young John Rubinstein and Stephanie Bueler on a lab skating trip at Nathan Philip Square in Toronto..
A slightly older John Rubinstein and Stephanie Bueler.
A chocolate cake with red writing that reads 2006, 2026, JLR, SAB
In Jan 2006 I started my dream job: running my own research group at The Hospital for Sick Children in my home town, Toronto. Stephanie Bueler started as lab manager on Day 1.
Many students, postdocs, papers, and microscopes later we're still going strong - and Stephanie is still putting up with me!
The Gonzalez Lab at Columbia University is seeking a scientific leader!
Join us in a Research Scientist position, driving single-molecule, structural, and biochemical studies of translation, translational control, and other RNA-based processes.
Apply: apply.interfolio.com/176949
Announcing the second round of 2025 SGP Rising Star Travel Awards for students and postdocs. The $500 awards can be used for meetings held up to 1 year from notification. Apply today! Deadline: 31 December 2025 sgpweb.org/awards/risin...
🌟 WeINSPIREBio is hosting its first event!
On Dec 4, we’re running a webinar:
Structures of Success: Career Journeys of Women in Structural Biology
If you work in SB, drug discovery, or just like hearing career stories from brilliant people, join us! And please share 🙏🏼
lnkd.in/ewjD5WPt
#cryoEM
I needed this…
Oh, Canada. What are you doing to us?
Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...
Go New Jersey!!!
