But one of the better breweries in the area! IMO

A new study published in the April issue of #GENETICS uses #yeast model to identify that the ribosomal protein ASC1 reduces TDP-43 toxicity via autophagy, revealing a new regulatory pathway in the neurodegenerative disease ALS.

🔗 buff.ly/bzGCa41

Currently, the framework is heavily oriented toward antibacterial resistance, leaving antifungal resistance (AFR) dangerously neglected.

Faculty member, Dr. David Boulware, is among the experts advocating for the immediate integration of AFR into these global One Health commitments. #IDSky

TBF I enjoyed the first few stories, which were 20-30 pages, when they transitioned to 5-8 pages writings, it didn’t do much for me.

Reading Robert W. Chambers The King in Yellow. Starting to think I’m not the target market for the short story. If there’s no meat on the bone, the idea of ‘exploring themes’ when there’s really no exploration is annoying to me. Make it a haiku and let me get on with my day.

Among the alleged abuses, the report left out being a woman in the Trump admin.

"BRCA2, A Conserved Rad51 Mediator Lost in Ascomycetes"
by H Tsubouchi & H Iwasaki

"BRCA2 is a conserved primary mediator of Rad51-dependent HR in eukaryotes [and] fungal BRCA2 provides a simplified model for understanding its core functions."

FREE till Jun 9
authors.elsevier.com/a/1mzMucQbJI...

Found the second tick of the season. In 20 plus years never seen ticks in the area this early

Cat laying in a tree stand

Gracie stares in judgement…as per usual

A graphic with text that reads "ASPB Advocacy and Science Policy Update. Call to action: Support the NSF BIO Plant Biology Act. Strengthening U.S. Leadership in Plant Science."

The NSF BIO Plant Biology Act (H.R.7949) would strengthen investments in plant and microbial research—helping drive innovation and protect U.S. agriculture. Learn why it matters and how to take action 👉 buff.ly/xRu6Eqz #PlantScience #SciencePolicy

From “The Simpsons” house genius John Swartzwelder, interviewed in The New Yorker by Mike Sacks

Why scientists are nervous about fungi They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

They can pose a threat to human health — yeast infections are but one example. Scientists say not enough attention is paid to their ability to develop resistance to medications that treat them.

How do haploid and diploid cells evolve in the natural isolates of the #yeast Saccharomyces cerevisiae?

Dive deep into these experimental results that reveal genetic signatures in haploid vs diploid strains.

Paper in #G3journal: 🔗 buff.ly/J4kixfb

50 medical mycologists put their shoulder behind an action plan to mitigate the rising threat of antifungal drug resistance. Check out in Nature Medicine. @youngecmm.bsky.social @ecmmcandidaiv.bsky.social @ishamycology.bsky.social @bsmm-meeting.bsky.social @mrccmm.bsky.social

Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...

@hhmi-science.bsky.social's
#FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits

Stable, sustained support can transform your career:

Senior Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

Something for next Fall’s Eukaryotic Micro class maybe

Unlocking how dogs' fungal ear infections evade treatment Mutations in a key protein make a yeast found in dogs with common outer ear infections more resistant to the topical antifungals used to treat it, veterinarians and pathobiologists at the University…

How #dogs' #fungal #ear #infections evade treatment ...

| #fungi | #yeast | #MicroSky | #antifungals | #pathobiology | #canine | Via @sciencex.bsky.social

Issue Information No abstract is available for this article.

The new #Yeast issue of January-March 2026 (Volume 43, Number 1-2) is now out, with a review on the role of Rad9 in DNA repair, and three research articles spanning the isolation of yeast species from flowers and honeys, and the effects of furanic compounds.

onlinelibrary.wiley.com/doi/10.1002/...

Two C. elegans worms with eggs and hatched larvae. Red highlights fluorescently labeled cellular ribosomes. Bright regions are the reproductive organs (gonads).

Can changes in the #proteome be transmitted from parents to offspring? @betowbin.bsky.social &co study #intergenerational effects of #DietaryRestriction in #Celegans, showing that maternal mTORC1 governs transfer of #ribosomes, so modulating growth & development @plosbiology.org 🧪 plos.io/4tMpQJe

The last time I tried to engage with Jay Bhattacharya in dialogue I ended up on administrative leave. 🤷‍♀️

Wait. So Trump is threatening to blockade the Straight of Hormuz? Does he think two blockades cancel each other out and his blockade nullifies Iran’s? Are blockades negative numbers you simply multiply?

Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells Uev1A and APC/C degrade CycA to counteract oncogenic Ras, thereby protecting against cell death in polyploid Drosophila nurse cells and suppressing overgrowth in diploid germline and human colorectal...

Uev1A counteracts oncogenic <i>Ras</i> stimuli in both polyploid and diploid cells

My +1 heart is in fact a thumbs down 😡

Today is like watching Michelangelo paint the Sistene Chapel while reading about the ongoing Hundred Years' War.

As awe-inspiring as Curiousity and Perseverance landings on Mars. 😄 Thank you (non-Trump) NASA et al!!!!

Just want to see the crew exit the return vehicle

Awesome crew discussing amongst themselves whether Trump still in charge or if maybe just maybe other ape species have become the dominant species.

Tears to the eyes!

Splashdown!!! The wonders of humanity.....juxtaposed by the worst of humanity that hits our feeds every minute. Tears man, nothing but tears of joy for the Artemis II crew and team that made this happen.

#FUCKTRUMP

You need to make AI guidelines for your lab Here's why you should, and how to start

Still thinking about this. Thoughts welcome...

You need to make AI guidelines for your lab
open.substack.com/pub/blekhman...