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Posts by Mark Wossidlo

We‘re looking for a motivated Master student to join our team!

Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬

Then please apply!
#optogenetics #metabolism #devbio #hESCs

Please RT. Thank you!🙏

2 months ago 38 39 0 0
Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis | Journal of Experimental Medicine | Rockefeller University Press In this study, Gawish et al. show that RNA editing of the actin cross-linker FLNA is similarly regulated in mice and humans and that the targeted induction

📢 New publication from the Vesely group in @jem.org!
Led by Riem Gawish, this study shows that edited Filamin A in myeloid cells can protect mice from chemically induced colitis.
Congratulations to all involved in this exciting collaborative work!

🧬 👉 rupress.org/jem/article/...

10 months ago 3 1 0 0

Really proud to be part of this! This study puts hard numbers on something we’ve all been wondering: How much small RNA do sperm actually carry? 📉
Turns out — much less than expected.
A must-read for anyone interested in RNA-based inheritance and how we model it. 🧬🤔

10 months ago 0 0 0 0
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Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14

11 months ago 211 66 23 9
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Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.

We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵

11 months ago 98 38 9 4
Video

This guy nails it

This is why basic (aka blue skies) research is so important. It’s fundamental to discoveries that change lives and improve humanity

1 year ago 159 67 1 2
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2024 is coming to a close, and what a year it was for the GMI! As we recap this year’s highlights, let’s start with the biggest achievements by our Students and Postdocs in 2024.

1 year ago 10 3 1 0

Congratulations Christa! Looking forward for exciting results!

1 year ago 2 0 1 0
Redirecting

By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12

1 year ago 226 84 14 11
Poster for 2024 Asilomar Chromatin Conference showing image of view of Monterey Bay from Pacific Grove beach with blue skies and blue ocean beyond the rocky shores. There are images of the four keynote speakers, a listing of session topics, and acknowledgement of the meeting sponsors.

Poster for 2024 Asilomar Chromatin Conference showing image of view of Monterey Bay from Pacific Grove beach with blue skies and blue ocean beyond the rocky shores. There are images of the four keynote speakers, a listing of session topics, and acknowledgement of the meeting sponsors.

Let’s go! Less than two weeks to the 46th International Annual Asilomar #Chromatin, #Chromosomes, and #Epigenetics Conference Dec 12-15, 2024, in Pacific Grove, CA! asilomarchromatin.com #AsilomarChromatin

1 year ago 8 4 0 0
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Application The graduate program IMPRS for Biology And Computation (IMPRS-BAC) provides an education for students at the interface of molecular life sciences and computational sciences. This is based on perspective and supervision from both ends - experimental and computational - and suits students with degrees in molecular biology, biochemistry, mathematics, bioinformatics or any related areas. If you have a passion for epigenetics, bioinformatics, developmental biology, mathematics, sequence analysis, gene regulation, RNA biology, mechanobiology, protein biochemistry, stem cells and differentiation, statistics, molecular evolution or biophysics and want to work at the Max Planck Institute for Molecular Genetics or the Freie Universität Berlin - this is the program for you!

Our lab members are off to cool new jobs (including faculty 🎉) so we are looking for new team members. Experimental postdoc prioritized, but do get in touch if you think you are a good fit.

Also, our PhD program is currently accepting applications: www.molgen.mpg.de/IMPRS/applic...

1 year ago 36 31 2 3

Hello Bluesky! Excited to reconnect with a vibrant and healthy scientific community. Eager to explore #epigenetics and #DNAmethylation insights from the experts here!

1 year ago 14 2 1 0