#Article in #MedComm
Ramalin Ameliorates #Alzheimer's Disease Pathology by Targeting #BACE1, #HDAC6, and #MAPK Pathways doi.org/10.1002/mco2...
#Ramalin restores synaptic function impaired by #Aβ toxicity and improves cognitive performance in #AD mouse models.
#NLRP3
🔥Hot Off the Press | #Cell: Synthetic-biased agonists against #CCKBR-Gq signaling can be beneficial for AD:
👉CCKBR activation alleviates memory decline in vivo
👉#3r1 ameliorates memory impairment in animal models
👉3r1 diminishes #Aβ deposition + inhibits #tau phosphorylation
#RecercaUB | “El nostre estudi va demostrar una notable eficàcia per aconseguir una ràpida eliminació de #Aβ, restaurar la funció saludable en la barrera hematoencefàlica i conduir a una sorprenent reversió de la patologia del #Alzheimer”, diu Lorena Ruiz Pérez.
Infographic showing how altered microRNA expression contributes to Alzheimer’s pathology — promoting amyloid-beta plaques, neurofibrillary tangles, neuroinflammation, and neuronal apoptosis in the hippocampus
In #Alzheimer dysregulated #microRNAs influence key #pathological features —
🧩 #Aβ plaque buildup
🧩 #Tau #hyperphosphorylation & neurofibrillary tangles
🧩 #Neuroinflammation & apoptosis in the hippocampus
Understanding these miRNA shifts opens doors to early diagnosis & targeted therapies.
A recent study from the Rudolf Virchow Center maps the binding sites of 20 key antibodies, including biosimilars to recently approved therapeutics for #Alzheimer's disease, revealing how structural variants of #Aβ impact detection.
Read the blog 🔎 https://bit.ly/416lxMM
The July edition of "What's New at StressMarq?" is here! Check out our #PivotalLinks recognition, #sustainability initiatives, next exhibit location, and how our #αSyn, #Tau & #Aβ oligomers are driving #neurodegeneration research forward!
Read it here 💫 https://bit.ly/3IcDfI9
Product Citation: In collaboration with Bioneer, StressMarq's #AmyloidBeta 1-42 PFFs & Oligomers were used to model microglia cytokine immune responses in iPSC-derived #microglia harboring genetic mutations linked to #Alzheimer's disease.
Bioneer Poster ✉️ bit.ly/3YNgvnd
#Aβ 1-42 ⛅ bit.ly/499p5iK
🧠#Alzheimer’s picked a fight... but #Antidepressants hit back!💥 #Duloxetine & #Mirtazapine shield brain cells from #Aβ damage⚡🛡️Bye #OxidativeStress! Hello #Hope!🧬 A game-changer for #eurodegeneration🔥 @mdpiopenaccess.bsky.social
#Neuroscience
👇 Dive in Share the future
📖 doi.org/10.3390/biom...
🧠#Alzheimer’s picked a fight... but #Antidepressants hit back!💥 #Duloxetine & #Mirtazapine shield brain cells from #Aβ damage⚡🛡️Bye #OxidativeStress! Hello #Hope!🧬 A game-changer for #eurodegeneration🔥 @mdpiopenaccess.bsky.social #Neuroscience
👇 Dive in Share the future
📖 doi.org/10.3390/biom...
