Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways Ramalin alleviates Alzheimer's disease pathology by selectively inhibiting HDAC6, reducing BACE1 levels, and suppressing neuroinflammation through downregulation of the NLRP3 inflammasome and iNOS. I...

#Article in #MedComm

Ramalin Ameliorates #Alzheimer's Disease Pathology by Targeting #BACE1, #HDAC6, and #MAPK Pathways doi.org/10.1002/mco2...

#Ramalin restores synaptic function impaired by #Aβ toxicity and improves cognitive performance in #AD mouse models.

#NLRP3

BACE1 in Alzheimer’s Disease

Drawing: “Worn out sack of memories”
Protein: #BACE1 (www.rcsb.org/structure/1SGZ)

#Alzheimer’s disease is a progressive brain disorder that slowly destroys memory, thinking skills, and the ability to carry out simple tasks.