#ACAT1 acquires a nuclear role in #ColorectalCancer, where S60 phosphorylation enables p50 acetylation, relieves #NFκB repression, enhances #NKcell recruitment, while nutrient stress blocks this axis and drives #ImmuneEvasion and poor prognosis.

#STTT: doi.org/10.1038/s413...

#ACAT1 acts as a nuclear #acetyltransferase in #ColorectalCancer, where S60-phosphorylated ACAT1 acetylates p50 to enhance immune-related gene expression, promote #NaturalKiller cell recruitment, & suppress #tumor growth. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...