U01.03.005 Anaerobes Anaerobes are bacteria that thrive in environments lacking oxygen. They are part of normal flora but can cause disease when introduced into sterile sites. Key anaerobes include Clostridium, Bacteroides, Fusobacterium, and Actinomyces, known for producing foul-smelling infections and gas formation.

Master anaerobic bacteria, their features, and major infections caused by Clostridium, Bacteroides, and others. #Anaerobes #Microbiology #Clostridium #Bacteroides #Fusobacterium #Actinomyces #MedicalEducation #USMLE #Pathology #BacterialMetabolism #ClinicalMicrobiology

Treatment of actinomycosis

For the treatment of actinomycosis are used: Penicillin, Co-trimoxazole.

#actinomyces #actinomycosis #infection #Actinomycosisinfection

Ct may help but definitive dx: histology actinomycotic sulfur granules and/or culture. Preferred culture from pus. Sulfur granules: colonies of #Actinomyces zone of granulation tissue surrounding >1 oval eosinophilic granules. Beaded or filamentous, non–AFB, gram+ bacilli

DDX Nocardia can have a similar appearance on gram stain, it usually infects immunocompromised hosts; moreover, Nocardia is modified AFB positive whereas #Actinomyces is not.

#Actinomyces most commonly involves jaw, lung & intra-abdominal sites. Hepatic actinomycosis represents 5% of actinomycosis & may result either from direct extension from contiguous focus or hematogenous spread. It is usually related to a breach in GI mucosa, mostly polymicrobial

Ct may help but definitive dx: histology actinomycotic sulfur granules and/or culture. Preferred culture from pus. Sulfur granules: colonies of #Actinomyces zone of granulation tissue surrounding >1 oval eosinophilic granules. Beaded or filamentous, non–AFB, gram+ bacilli #IDsky

Using Nanopore Sequencing to Obtain Complete Bacterial Genomes from Saliva Samples | mSystems Obtaining complete and accurate genomes is crucial to the study of any organism. Previously, obtaining complete genomes of bacteria, including those of the human microbiome, frequently required isolation of the organism, as well as low-throughput, manual ...

New publication is live today! Obtaining complete bacterial genomes from saliva samples using @nanopore sequencing.

#microbiology #nanopore #dentistry #genomics #Bioinformatics #saccharibacteria #actinomyces
@JCVenterInst @UCSDMedSchool @mSystemsJ

journals.asm.org/doi/10.1128/ms…

NCBI - WWW Error Blocked Diagnostic Your access to the NCBI website at www.ncbi.nlm.nih.gov has been temporarily blocked due to a possible misuse/abuse situation involving your site. This is not an indication of a security issue such as a virus or attack. It could be something as simple as a run away script or learning how to better use E-utilities, http://www.ncbi.nlm.nih.gov/books/NBK25497/, for more efficient work such that your work does not impact the ability of other researchers to also use our site. To restore access and understand how to better interact with our site to avoid this in the future, please have your system administrator contact info@ncbi.nlm.nih.gov.

First complete genome of Actinomyces graevenitzii released in GenBank today.

2,130,963 bp

Completed using @nanopore, @illumina, metaFlye, and Polypolish.#Bioinformatics #microbiology #actinomyces #genomics #metagenomics #dentistry

ncbi.nlm.nih.gov/nuccore/CP0970…