Development of the Windmill Model for Mapping Older Adults’ Intrinsic Capacity Using Digital Twin Technology: Descriptive Qualitative Study Background: Intrinsic capacity (IC) refers to the sum of the physical and mental capacities of an individual. Conventional IC assessment requires substantial temporal and human resources. Digital twin (DT) technology emerges as a promising solution for efficiently mapping ICs. Objective: This study aims to explore older adults’ perspectives on the DT technology and their perceptions of how it could effectively represent their ICs. Methods: A qualitative study was used. Face-to-face semistructured interviews with 23 older adults were conducted. The interviews were transcribed verbatim and analyzed via content analysis approach. Results: The analysis identified five themes and 16 subthemes: (1) “opt for or not my digital twin,” revealing the older adults’ decisions regarding whether to use DT technology for mapping ICs; (2) “my ideal digital avatar,” describing the older adults’ preferences for personalized digital avatar appearances; (3) “my digital twin maps my intrinsic capacity,” highlighting how multimodal reminders and synchronized avatar changes enhanced their comprehension of ICs; (4) “the benefits my digital twin can deliver,” emphasizing the potential of the DT system to provide feedback services to older adults; (5) “some expectations for my digital twin,” outlining their expectations for DT technology. Based on the above insights, a conceptual model, “windmill” model, was further developed to better understand how to build DTs of older adults and map their ICs. Conclusions: DT technology was a promising tool for mapping ICs of older adults. Furthermore, the “windmill” model provided a framework to build tailored DTs. The findings of this study could provide references to develop DT model to support IC management.

New in JMIR Aging: Development of the Windmill Model for Mapping Older Adults’ Intrinsic Capacity Using Digital Twin Technology: Descriptive Qualitative Study #DigitalTwin #IntrinsicCapacity #AgingResearch #OlderAdults #HealthTech

🌍 Join Us at the International Conference on Geriatrics & Gerontology 2026!
📅 August 07–08, 2026
📍 Amsterdam, Netherlands
🔔 Register Now & Secure Your Spot: geriatrics-gerontology.inovinemeetings.com/registration...

#geriatricsconference #gerontology2026 #agingresearch #inovineconferences

MRI Brain scan image

Staying mentally active matters.
via The Washington Post
A new long-term study finds that replacing passive activities (like TV) with engaging ones (reading, puzzles, computer use) may reduce dementia risk—even small daily changes add up. #AgingResearch
www.washingtonpost.com/opinions/202...

How does aging work from an evolutionary perspective? Why do different species age at different rates?

Understanding the evolution of aging and senescence can inform us how we think about age-related diseases and healthy longevity.

#ISEMPH #EvolutionaryMedicine #AgingResearch #Geroscience

📢#CallforPapers:
Aging-US is honoring Dr. Mikhail (Misha) Blagosklonny with a special #collection.

Submit your #research, reviews and perspectives on mTOR, rapamycin, #aging, cancer & more.

📅 Deadline: May 31, 2026

🔗 Submission Details:
www.aging-us.com/mikhail-blag...

#agingresearch

e are delighted to invite you to the International Conference on Geriatrics & Gerontology 2026
📅 August 07–08, 2026
📍 Amsterdam, Netherlands
🚀 : geriatrics-gerontology.inovinemeetings.com/registration...

#geriatricsconference #gerontology2026 #agingresearch #healthyaging #inovineconferences

📢 #CallForPapers: Special Collection on Cognitive Aging

Aging-US seeks #research on cellular and molecular mechanisms of #cognitiveaging, plus psychosocial, behavioral, and environmental factors.

🗓️ Deadline: July 31, 2026

🔗 www.aging-us.com/call-for-pap...

#AgingResearch

If we could slow aging… how would we know?

Episode 23 of Decoding Longevity explores one of the biggest challenges in longevity science — measuring impact in humans.

🎧 Listen:
Spotify → open.spotify.com/episode/2r1E...
YouTube → youtu.be/kuxVfl_gKfE?...

#agingresearch #healthspan

📢 #CallforPapers:
Aging-US invites #submissions on cellular #senescence - its mechanisms, functions & clinical applications - in memory of Dr. Judith Campisi.

📅 Deadline: May 31, 2026

🔗 Submission Details:
www.aging-us.com/judith-campi...

#AgingResearch #OA #Aging #Publishing

🌍 Exciting Announcement!
We are delighted to announce the International Conference on Geriatrics & Gerontology
📅 August 07–08, 2026
📍 Amsterdam, Netherlands
👉: geriatrics-gerontology.inovinemeetings.com/submit-abstr...

#geriatricsconference #gerontology2026 #agingresearch #inovineconferences

Validity of Smartphone-Based Measurement for Assessing Lower Limb Power for Sarcopenia and Frailty Discrimination: Cross-Sectional Study Background: Increasing life expectancy has increased focus on the health-related consequences of aging, such as sarcopenia and frailty. Given the prevalence of these conditions among older individuals and the frequent resulting long-term care needs, early detection and intervention are crucial. Objective: This study aimed to validate a novel smartphone-based system measuring acceleration during the sit-to-stand movement to detect sarcopenia and frailty. Methods: Participants were 587 individuals from the Otassha study cohort who underwent health assessments in 2023, of whom 569 (96.9%) completed 2 supervised sit-to-stand trials while holding a smartphone on the lower abdomen. Sarcopenia and frailty were diagnosed using the Asian Working Group for Sarcopenia 2019 criteria and the revised Japanese Cardiovascular Health Study criteria, respectively. Peak force, rising time (T1), and stabilization time (T2) were extracted from acceleration signals, and reproducibility was examined using the intraclass correlation coefficient (ICC(2,1)). Predictive models were developed using elastic net penalized logistic regression, and model performance was evaluated using 500 bootstrap resamples. Benchmark models using age and sex, walking speed, and grip strength were also constructed for comparison. Results: Sarcopenia and frailty were identified in 16.7% (95/569) and 9% (51/569) of the participants, respectively. Peak force demonstrated excellent reliability (ICC=0.863), whereas T1 and T2 showed lower reproducibility (ICC

JMIR Formative Res: Validity of Smartphone-Based Measurement for Assessing Lower Limb Power for Sarcopenia and Frailty Discrimination: Cross-Sectional Study #Sarcopenia #Frailty #AgingResearch #HealthTechnology #SmartphoneHealth

🚨 Registrations Now Open!
Join us at the International Conference on Geriatrics & Gerontology 🌍
📅 August 07–08, 2026
📍 Amsterdam, Netherlands
👉 Register now : geriatrics-gerontology.inovinemeetings.com/registration...

#geriatricsconference #gerontology2026 #agingresearch #inovineconferences

Scientists found a protein that drives brain aging — and how to stop it UCSF Scientists discovered that FTL1 protein drives brain aging in mice. Lowering FTL1 reversed memo...

UCSF Scientists discovered that FTL1 protein drives brain aging in mice. Lowering FTL1 reversed memory decline. Targeting FTL1 could lead to future therapies. More in Nature Aging. #AgingResearch #News

🌍 International Conference on Geriatrics & Gerontology 2026
📍 Amsterdam, Netherlands
📅 August 07–08, 2026
📧 gerontology@inovinemeetings.com
🚨 Limited slots available – Don’t miss this opportunity!

#geriatricsconference #gerontology2026 #agingresearch #inovineconferences

What if aging is less about disease — and more about losing physiological reserve?

In Episode 23 of Decoding Longevity, Stephen Kritchevsky shares how mobility, strength, and resilience shape how we age.

#longevity #agingresearch #healthspan

What if the most important question in aging isn’t “how long?” — but “how well?”

In this episode of Decoding Longevity, Stephen Kritchevsky shares insights on mobility, metabolism, and what really shapes healthy aging.

#longevity #agingresearch #healthspan

Omega-3 may slow biological aging 🧬
A clinical trial shows measurable impact at the DNA level—especially when paired with vitamin D + exercise.
Aging is becoming modifiable, not just inevitable.
Read:
www.goodhousekeeping.com/health/diet-...
#Longevity #AgingResearch #Healthspan

Lifting weights can slow down biological brain aging in older adults A new study published in GeroScience suggests that older adults who lift weights can actively slow down their biological brain aging. These findings provide evidence that regular strength training tends to keep the mind younger and healthier.

Lifting weights can slow down biological brain aging in older adults #Science #HealthandMedicine #MentalHealth #BrainHealth #AgingResearch #WeightLifting

www.psypost.org/lifting-weights-can-slow...

📢 #CallForPapers: Special Collection on Cognitive Aging

Aging-US seeks #research on cellular and molecular mechanisms of #cognitiveaging, plus psychosocial, behavioral, and environmental factors.

🗓️ Deadline: March 31, 2026

🔗 www.aging-us.com/call-for-pap...

#AgingResearch

International Conference on Geriatrics & Gerontology 2026
📍Amsterdam, Netherlands.
📅 August 07–08, 2026
#CPD & #Ce
🔗geriatrics-gerontology.inovinemeetings.com/submit-abstract.php

#geriatricsconference #gerontology2026 #agingresearch #healthyaging #inovineconferences

As a medical school professor, I taught that aging was caused by DNA mutations accumulating over time.
A landmark study from my friend Dave Sinclair's team in... www.cell.com/cell/fulltext/S0092-8674...

#Epigenetics #Longevity #AgingResearch #MetabolicHealth #HealthLongevitySecrets

We're pleased to share that Dr. Paterson won the 2025 Catalyst Grant for her project entitled "Modelling the Impacts of Life Course Enrichment and Depletion Factors on Cognitive Aging and Brain Health Trajectories using Canadian Longitudinal Study on Aging Data". #agingresearch #clsa #cognitiveaging

🎉 Congrats to AGE 2026 Early Career Scholar Awardee Alberto Williams-Medina (Albert Einstein College of Medicine)!
His research studies brain aging and cognitive resilience — advancing translational strategies to preserve function in neurodegenerative disease.
#Geroscience #AgingResearch

🎧 Listen here:
Spotify → open.spotify.com/episode/2z0c...
YouTube → youtu.be/ZAoMhgyn1Nc?...
Apple Podcasts → podcasts.apple.com/tr/podcast/f...

#longevity #healthspan #agingresearch

Why Aging Lungs Turn Mild Infections Into Life-Threatening Illness Aging lungs may be sabotaging themselves—fueling runaway inflammation that turns mild infections into life-threatening illness.

Why Aging Lungs Turn Mild Infections Into Life-Threatening Illness #Science #HealthandMedicine #InfectiousDiseases #AgingResearch #LungHealth

scitechdaily.com/why-aging-lungs-turn-mil...

🌍 International Conference on Geriatrics & Gerontology 2026
Join us on 📅August 07–08, 2026 |
📍Amsterdam, Netherlands
🎤 Call for Abstracts Now Open : geriatrics-gerontology.inovinemeetings.com/submit-abstr...

#geriatricsconference #gerontology2026 #agingresearch #healthyaging

Can we predict health,
Or when flies drop like fall leaves?
Yes, chemotypes can!

www.biorxiv.org/content/10.6...

#Drosophila #AgingResearch #sciku
@thescikuproject.bsky.social

🎉 Congrats to #AGE2026 Early Career Scholar Awardee Piper Wilburn- #IndianaUniversitySchoolOfMedicine.
Recognized by the #AmericanAgingAssociation, her research studies how the bone marrow niche shapes stem cell function and transplant outcomes in aging.
#Geroscience #AgingResearch

🎉 Congrats to #AGE2026 Early Career Scholar Awardee Michaela Vance - #UniversityofOklahomaHealthCampus!

Recognized by the #AmericanAgingAssociation, her research studies vascular fragility in the aging brain and how cellular transitions drive cognitive decline.

#Geroscience #AgingResearch

From Science to Strategy: How Policy Will Shape the Future of Longevity — A Conversation with Dylan Livingston

🎧 Listen here:
🟢 Spotify → open.spotify.com/episode/2z0c...
🔴 YouTube → youtu.be/ZAoMhgyn1Nc?...
🟣 Apple Podcasts → podcasts.apple.com/tr/podcast/f...

#longevity #healthspan #agingresearch