This review maps the genetic landscape of #AnaplasticThyroidCancer, spotlighting #MAPK & PI3K-AKT-mTOR signaling to connect pathogenic mechanisms with advances in targeted therapies, #immunotherapies, and diagnostic development.

#OpenAccess: doi.org/10.1016/j.ge...

This review explores the #MolecularMechanisms and #therapeutic advances in #AnaplasticThyroidCancer, focusing on the #MAPK and #PI3K-#AKT-mTOR pathways, diagnostics, and evolving treatment strategies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Evaluation of Treatment Response and Survival Outcomes in Anaplastic Thyroid Cancer Patients Following Surgery With and Without Other Treatment Modalities: A Systematic Review Background and Aims Anaplastic thyroid carcinoma (ATC) is a rare type of malignancy ranking among the most aggressive diseases globally, with an extremely poor prognosis. No optimal standardized tre...

Our review of +16,000 patients shows that combining #surgery with chemoradiotherapy improves outcomes in Stage IVA and IVB #AnaplasticThyroidCancer. Tumor size influences utcomes. #thyroidectomy #ThyroidNeoplasm #SystematicReview onlinelibrary.wiley.com/doi/10.1002/...

Anaplastic thyroid cancer: Genetic roles, targeted therapy, and immunotherapy

This review details the signaling pathways involved in the #pathogenesis & progression of #AnaplasticThyroidCancer (ATC), the available targeted therapies & #immunotherapies, and summarizes the advances & challenges in the current diagnostic approaches for ATC. #medsky

#OpenAccess: buff.ly/K63hF0I