Rewiring of oncogenic signaling in #DrugResistance is a moving target. In our new study, we used biophysical phosphoproteomics to investigate #BRAF mutant cancer, linking phosphorylation changes to protein function and #MolecularMechanisms through #Multi-Omics integration.
tinyurl.com/funsignaling
🧬Single-cell spatial transcriptomics reveals potential molecular mechanisms of Abelmoschus manihot (L.) medic in treating diabetic kidney disease
#scRNAseq #MolecularMechanisms #iMeta onlinelibrary.wiley.com/doi/10.1002/...
New insights into how the immunological synapse organizes signaling, controls immune activation, and shapes therapeutic strategies across disease contexts.
#ImmunologicalSynapse #TCells #ImmuneSignaling #MolecularMechanisms #Immunotherapy
www.nature.com/articles/s41...
This latest review highlights the #MolecularMechanisms connecting #Autophagy & #Ferroptosis in #Diabetes, demonstrating how they shape #disease progression & emphasizing their potential as targets for #therapeutic intervention. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
This review explores the #MolecularMechanisms and #therapeutic advances in #AnaplasticThyroidCancer, focusing on the #MAPK and #PI3K-#AKT-mTOR pathways, diagnostics, and evolving treatment strategies. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
This review systematically summarizes intra-tumoral microbiota in #Cancers, highlighting their #MolecularMechanisms, #therapeutic roles, and diagnostic/prognostic potential for advancing precision cancer treatments. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
This review unpacks the #MolecularMechanisms behind #Endocrine-associated disorders and highlights cutting-edge advances in #EpigeneticTherapies, underscoring their potential to reshape treatment strategies. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
This study mapped ageing-related DEGs and built an A-score model using #MachineLearning, spotlighting #ImmuneCells as key players across HFpEF subtypes. It offers fresh insights into the #Immune #MolecularMechanisms driving #HFpEF. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
Symposium Plan: Molecular Mechanisms Monday, October 6, 2025, 3 p.m., Seminar Room FNO - 01/117 3 p.m. Wieland B. Huttner Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany What made our brain so big and us smarter than Neandertals? 4 p.m. Victor Borrell Franco Institute of Neuroscience, CSIC-UMH, San Juan de Alicante, Spain Epigenetic and cellular regulation of cortex expansion and folding 5 p.m. Coffee break 5.15 p.m. Delilah Hendriks Princess Maxima Center, Utrecht, NL Human brain organoids: from novel models to studies of development and disease Host: Asisa Muchamedin Guests are welcome!
Next week, Oct 6th 2025 @ruhr-uni-bochum.de:
IGSN Symposium:
Human Brain Development and the Use of Cerebral Organoids to Decipher Cellular and Molecular Mechanisms.
More info: philosophy-cognition.com/cmc/events
#cognition #IGSN #Brain #MolecularMechanisms #mind #Neuroscience #Development
This seminar is a unique forum designed to foster interdisciplinary venom research—spanning #ecology, #evolutionarybiology, #molecularmechanisms, and #translational applications. Attendees get to present their work, engage in deep discussion, and build collaborations across fields.
This review uncovers how aerobic exercise alleviates #Anxiety through #MolecularMechanisms, endorsing aerobic exercise as a powerful, #NonPharmacological #Neurotherapy in #MentalHealthCare. #medsky
Click to read:
link.springer.com/article/10.1...
Introducing DREAMER, a groundbreaking tool that identifies mechanisms of #AdverseDrugReactions (ADRs) by linking drug and disease phenotypes to protein interaction networks. Here, DREAMER revealed #MolecularMechanisms behind 67 ADRs.
www.sciencedirect.com/science/arti...
👇What’s the biology behind PVATxASCVD? LAD FAI predicts MACE. #OutsideIn #shiftingParadigm #MolecularMechanisms
(1/3) Ever wonder if there is anything in common between people studying #plasticity, #variability, #robustness, #bethedging, #variance, error-prone #molecularmechanisms? Might we all be thinking about different manifestations of Biological Noise? @official-smbe.bsky.social @mpi-bio-fml.bsky.social
