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Interesting publications on CaCO3 #mineralization/ #biomineralization

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Proteins and Water Control the Stability of the Intracellular Amorphous Calcium Carbonate Inclusions Formed by Cyanobacteria The formation of stable intracellular amorphous calcium carbonate (ACC) inclusions is widespread among bacteria, yet the mechanisms underlying their long-term stabilization remain unresolved. In this ...

How do #cyanobacteria keep amorphous calcium carbonate (ACC) stable inside their cells?
Our new #JACS paper shows — via solid-state NMR — that a protein shell and water molecules stabilize ACC.
👉 pubs.acs.org/doi/full/10....

#biomineralization @biomin-impmc.bsky.social @ulbruxelles.bsky.social

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Cross and longitudinal sections of Trematoceras, a straight-shelled cephalopod. Each section also shown under cathodoluminescence, showing yellow, blue and red colours.

Cross and longitudinal sections of Trematoceras, a straight-shelled cephalopod. Each section also shown under cathodoluminescence, showing yellow, blue and red colours.

New paper out on the formation mechanism of cameral deposits in orthoceratoid cephalopds! This topic has been debated for more than 150 years and we now finally have a satisfying solution 🥳

https://doi.org/10.1111/pala.70032

#palaeontology #cephalopods […]

[Original post on ecoevo.social]

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Original post on sify.com

New Study Proves Gold Grows on Trees: What it means and why India should pay attention! In a ground breaking study that has since gone viral, scientists have discovered that trees do indeed grow go...

#Technology #biomineralization #CSIRO #Australia #Finland […]

[Original post on sify.com]

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Original post on greekreporter.com

Scientists Discover Tree That Can Make Gold Researchers in Finland have discovered that Norway spruce (Picea abies) trees can produce tiny gold particles within their needles due to the bacteria li...

#Environment #World #biomineralization #endophytes […]

[Original post on greekreporter.com]

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The image depicts a bright yellow segmented marine worm (Paralvinella hessleri) with feathery appendages at one end, shown against a black background.

The image depicts a bright yellow segmented marine worm (Paralvinella hessleri) with feathery appendages at one end, shown against a black background.

How does the alvinellid worm Paralvinella hessleri survive the toxic extremes of deep-sea #HydrothermalVents? A new study shows that it detoxifies its environment by forming orpiment minerals inside cells; this unique #biomineralization is a novel adaptation to toxic environments.🧪
plos.io/3HtVCZ6

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The image depicts a bright yellow segmented marine worm (Paralvinella hessleri) with feathery appendages at one end, shown against a black background.

The image depicts a bright yellow segmented marine worm (Paralvinella hessleri) with feathery appendages at one end, shown against a black background.

How does the alvinellid worm Paralvinella hessleri survive the toxic extremes of deep-sea #HydrothermalVents? A new study shows that it detoxifies its environment by forming orpiment minerals inside cells; this unique #biomineralization is a novel adaptation to toxic environments.🧪
plos.io/3HtVCZ6

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Biomineralization/Organomineralization-Dormancy

Biomineralization/Organomineralization-Dormancy

🌎🌏Organomineralization in the deep seabed polymetallic nodules: a matter of cell surface
Lilia Montoya & Elva Escobar-Briones
***
doi.org/10.1080/0149...
#Astrobiology #DeepSeaMining #Biomineralization

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Grant application rejected with the following comment:

"Further support for that one can detect the bone mineralization via Raman imaging would have strengthen the application."

Where do they find such reviewers? I'm perplexed! 🤯

#ramanspectroscopy #bone #biomineralization #science

🧪

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When you’re at #ECTS2025 to give a talk on the applications of Raman spectroscopy to study #bone #biomineralization, but find a Raman hairstylist instead.

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Shell formation is happening right here, right now!
If you look carefully, you can see the shape of the next chamber emerging faintly in the cytoplasm, a blueprint
From here it gradually calcifies
Behind the scenes of live observation research

#foraminifera #shell formation #biomineralization

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Nanoscale images of pyrite and other sufides in association with bacteria

Nanoscale images of pyrite and other sufides in association with bacteria

#GBI papers now out in the #Microbial #Biomineralization Collection: pyrite and iron sulfides www.cambridge.org/core/journal...

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Interesting work utilizing the excellent deep-sea #fossil record of foraminiferal #plankton shells to uncover evolutionary shifts in (developmental) growth timing & shell(/test) morphology relative to ancestors. I wonder how #biomineralization versus ocean chemistry interact with these shifts 🌊

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🦴🦷🔬🧬💎 Bringing together the “Mineralized Tissue Biology” community. Let me know if you'd like to be part of this.

go.bsky.app/MasDNUf

#academicsky #bone #teeth #biomineralization #biomaterials #science #biology #structuralbiology #cryoEM #electronmicroscopy #osteology #orthopaedics #starterpack

🧪

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🧪 The peer review system is truly broken! 😵‍💫

An author's perspective:
–All reviewers behave like Reviewer #2
–Reviewer comments are *do more* wishlists rather than factual scrutiny of reported data
–"Cite these (irrelevant) papers written by me"

2/2

#bone #biomaterials #biomineralization #science

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🦴 A picture is worth a thousand words—but this one speaks of #bone formation, remodelling, repair, and renewal!

The small white/grey dots are #osteocytes

🔬 Scanning electron microscopy after resin cast etching
🔍 rdcu.be/ebD4R

#biomaterials #biomineralization #microscopy #electronmicroscopy 🧪

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🦴🔬 Bone has (at least) two types of mineral: Intrafibrillar mineral (inside collagen fibrils) & Extrafibrillar mineral (outside). The mineral provides stiffness, while collagen provides toughness.

👉 Learn more:
doi.org/10.1016/j.ac...

#bone #biomineralization #apatite #collagen #biomaterials

🧪

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Doctoral student in Medical Science - Biodegradable Magnesium Implants and Bone Quality Doctoral position in Medical Science Project title: Impact of biodegradable magnesium-based implants on bone quality, biomineralisation, and

📢💡⚡ Open #PhD position at the Department of Biomaterials, University of Gothenburg 🇸🇪

bit.ly/40ItYNw

🦴🩻🔬🧪 The project will explore the impact of biodegradable magnesium-based #implants on #bone quality, #biomineralization, and bone marrow adiposity.

#biomaterials #microscopy #spectroscopy

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The physico-chemical characteristics of bone mineral remain heavily debated. On the nanoscale, bone mineral resides both inside and outside the collagen fibril as distinct compartments fused together into a cohesive continuum. On the micrometre level, larger aggregates are arranged in a staggered pattern described as crossfibrillar tessellation. Unlike geological and synthetic hydroxy(l)apatite, bone mineral is a unique form of apatite deficient in calcium and hydroxyl ions with distinctive carbonate and acid phosphate substitutions (CHAp), together with a minor contribution of amorphous calcium phosphate as a surface layer around a crystalline core of CHAp. In mammalian bone, an amorphous solid phase has not been observed, though an age-dependent shift in the amorphous-to-crystalline character is observed. Although octacalcium phosphate has been postulated as a bone mineral precursor, there is inconsistent evidence of calcium phosphate phases other than CHAp in the extracellular matrix. In association with micropetrosis, magnesium whitlockite is occasionally detected, indicating pathological calcification rather than a true extracellular matrix component. Therefore, the terms ‘biomimetic’ or ‘bone-like’ should be used cautiously in descriptions of synthetic biomaterials. The practice of reporting the calcium-to-phosphorus ratio (Ca/P) as proxy for bone mineral maturity oversimplifies the chemistry since both Ca2+ and PO43- ions are partially substituted. Moreover, non-mineral sources of phosphorus are ignored. Alternative compositional metrics should be considered. In the context of bone tissue and bone mineral, the term ‘mature’ must be used carefully, with clear criteria that consider both compositional and structural parameters and the potential impact on mechanical properties.

The physico-chemical characteristics of bone mineral remain heavily debated. On the nanoscale, bone mineral resides both inside and outside the collagen fibril as distinct compartments fused together into a cohesive continuum. On the micrometre level, larger aggregates are arranged in a staggered pattern described as crossfibrillar tessellation. Unlike geological and synthetic hydroxy(l)apatite, bone mineral is a unique form of apatite deficient in calcium and hydroxyl ions with distinctive carbonate and acid phosphate substitutions (CHAp), together with a minor contribution of amorphous calcium phosphate as a surface layer around a crystalline core of CHAp. In mammalian bone, an amorphous solid phase has not been observed, though an age-dependent shift in the amorphous-to-crystalline character is observed. Although octacalcium phosphate has been postulated as a bone mineral precursor, there is inconsistent evidence of calcium phosphate phases other than CHAp in the extracellular matrix. In association with micropetrosis, magnesium whitlockite is occasionally detected, indicating pathological calcification rather than a true extracellular matrix component. Therefore, the terms ‘biomimetic’ or ‘bone-like’ should be used cautiously in descriptions of synthetic biomaterials. The practice of reporting the calcium-to-phosphorus ratio (Ca/P) as proxy for bone mineral maturity oversimplifies the chemistry since both Ca2+ and PO43- ions are partially substituted. Moreover, non-mineral sources of phosphorus are ignored. Alternative compositional metrics should be considered. In the context of bone tissue and bone mineral, the term ‘mature’ must be used carefully, with clear criteria that consider both compositional and structural parameters and the potential impact on mechanical properties.

🔥Hot off the press🔥 "Revisiting the physical and chemical nature of the mineral component of bone" 🦴🔬
doi.org/10.1016/j.ac...
🧪

#bone #biomaterials #apatite #mineral #biomineralization #collagen #calcium #phosphate #hydroxyapatite #osteocyte #biology #medicine #osteology #osteoarchaeology

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Nice to see our perspective in the top 5 downloaded works in @cambridgeup.bsky.social research directions #biomineralization #sustainability #biocement and #syntheticbiology. A link to the paper here: www.cambridge.org/core/journal...

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Frontiers | In vitro model of bacterial biofilm mineralization in complex humid environments: a proof of concept study Bacteria in physiological environments can generate mineralizing biofilms, which are associated with diseases like periodontitis or kidney stones. Modelling ...

How were Legos & #E.Coli 🦠 used to develop an in vitro model to study #biofilm growth in humid environments?

The answer is in this paper by the InterDent multidisciplinary research group ( #MaterialsScience; #Physics; #Dentistry)

tinyurl.com/fexr8zr8

#Biomineralization
#WomenInSTEM
#skychem🧪

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Video

#Grogu spotted in #bone!

🦴🔬🧪🩻

#yoda #babyyoda #starwars #science #sciencefiction #imaging #microscopy #electronmicroscopy #biomineralization #osteocytes

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🦴🔬🩻🧪🥼 Last #imaging session for 2024. Looking at some #bone using an environmental scanning electron microscope! See you again in 2025!

#microscopy #bioimaging #electronmicroscopy #biomineralization #collagen #apatite #osteocytes

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Were early Archean carbonate factories major carbon sinks on the juvenile Earth? Abstract. Paleoarchean carbonates in the Pilbara Craton (Western Australia) are important archives for life and environment on early Earth. Amongst others, carbonates occur in interstitial spaces of c...

Were early Archean carbonate factories major carbon sinks on the juvenile Earth?
Nice #carbonate #biomineralization study just out in @egubg.bsky.social
bg.copernicus.org/articles/21/...

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To date, a wide spectrum of efforts have explored the design of osteogenic or osseoinductive biomaterials such as polymers, metals, and ceramics. Increasingly, efforts have also explored alternative fabrication approaches to create patient-specific implants. These efforts include adaptation of generative design principles and 3D printing to create unique geometries, methods to incorporate exogenous cell sources, and the use of conventional and exotic growth factor patterning and release approaches to further improve biological response. Here, we discuss the mechanisms of bone repair, the current available technologies, biomaterial design criteria, 3D printing as a fabrication method, and the influence of cells and growth factors on bone repair.

To date, a wide spectrum of efforts have explored the design of osteogenic or osseoinductive biomaterials such as polymers, metals, and ceramics. Increasingly, efforts have also explored alternative fabrication approaches to create patient-specific implants. These efforts include adaptation of generative design principles and 3D printing to create unique geometries, methods to incorporate exogenous cell sources, and the use of conventional and exotic growth factor patterning and release approaches to further improve biological response. Here, we discuss the mechanisms of bone repair, the current available technologies, biomaterial design criteria, 3D printing as a fabrication method, and the influence of cells and growth factors on bone repair.

🧪🔬🧬💠 Biomaterial design principles to accelerate #bone tissue #engineering

Dewey & Harley, 2022

doi.org/10.1007/978-...

#biomaterials #biomineralization #collagen #metals #autograft #tissueengineering #regenerativemedicine #implants #bioengineering #science #physics #biology #chemistry

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So, here's an amoeba that makes its shell out self-secreted siliceous "noodles". The organic glue that holds them together is laid down as a meshwork of dainty rosettes, each about 750 nanometers across. Lesquereusia spiralis: a commonplace marvel. #ProtistsOnSky #biomineralization

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#wordcloud 🧪🔬🦴💠

#bone #biomaterials #science #biology #chemistry #biomineralization

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This is a scanning electron microscopy image of osteocytes clinging to the surface of a titanium implant that has been surface modified by selective laser ablation to create a hierarchical, macro-micro-nano topography:
https://pubs.acs.org/doi/full/10.1021/ab500127y

The imaging technique is called Resin Cast Etching:
https://link.springer.com/article/10.1007/s00223-022-01058-9

This is a scanning electron microscopy image of osteocytes clinging to the surface of a titanium implant that has been surface modified by selective laser ablation to create a hierarchical, macro-micro-nano topography: https://pubs.acs.org/doi/full/10.1021/ab500127y The imaging technique is called Resin Cast Etching: https://link.springer.com/article/10.1007/s00223-022-01058-9

🦴🔬🧪 #Osteocytes in #bone around an osseointegrated titanium #implant

Osteocytes are mechanosensory cells that form a neuron-like network within bone and can regulate bone remodelling.

pubs.acs.org/doi/full/10....

#biomineralization #biology #orthopaedics #science #electronmicroscopy #imaging

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(a) BSE-SEM photomontage of a human rib viewed in cross-section. Local variations in mineralisation density, Haversian canals, resorption spaces, and osteocyte lacunae can be detected.
(b) Osteocyte lacunar density determined using BSE imaging.
(c) A cement line between osteonal bone and interstitial bone.
(d) The intertrabecular spaces in antler bone are occupied by primary osteons. Trabeculae (asterisks) and unremodelled islands of calcified cartilage (arrow) can be identified.
(e) Topographical BSE-SEM. For each 90° sector of an annular BSE detector, a separate image is recorded containing information sensitive to the direction of apparent illumination (arrows).
(f) Osteon pull-out under cyclic mechanical loading observed using SE imaging.
(g) Cell surface detail of osteoblasts on the surface of parietal bone.
(h) Osteoblasts appear to organise collagen fibrils through flat basal processes.
(i) Hypermineralised osteocyte lacuna containing mineralised apoptotic debris.
(j) Severely disorganised bone microstructure in melorheostosis.
(k) Bone with (right) and without (left) osteocytes.
(l) An osteocyte and associated canalicular network exposed by resin cast etching.
(m) Howship’s lacunae: longitudinally extended resorption (LER; left) and reticulate patch resorption (RPR; right) lacunae.
(n) Cryo-SEM. The combination of SE (above) and BSE (below) imaging provides morphological and compositional information.
SE = secondary electron mode; BSE = backscattered electron mode

(a) BSE-SEM photomontage of a human rib viewed in cross-section. Local variations in mineralisation density, Haversian canals, resorption spaces, and osteocyte lacunae can be detected. (b) Osteocyte lacunar density determined using BSE imaging. (c) A cement line between osteonal bone and interstitial bone. (d) The intertrabecular spaces in antler bone are occupied by primary osteons. Trabeculae (asterisks) and unremodelled islands of calcified cartilage (arrow) can be identified. (e) Topographical BSE-SEM. For each 90° sector of an annular BSE detector, a separate image is recorded containing information sensitive to the direction of apparent illumination (arrows). (f) Osteon pull-out under cyclic mechanical loading observed using SE imaging. (g) Cell surface detail of osteoblasts on the surface of parietal bone. (h) Osteoblasts appear to organise collagen fibrils through flat basal processes. (i) Hypermineralised osteocyte lacuna containing mineralised apoptotic debris. (j) Severely disorganised bone microstructure in melorheostosis. (k) Bone with (right) and without (left) osteocytes. (l) An osteocyte and associated canalicular network exposed by resin cast etching. (m) Howship’s lacunae: longitudinally extended resorption (LER; left) and reticulate patch resorption (RPR; right) lacunae. (n) Cryo-SEM. The combination of SE (above) and BSE (below) imaging provides morphological and compositional information. SE = secondary electron mode; BSE = backscattered electron mode

🧪 #Bone meets the scanning electron microscope 🦴🔬

Detailed description in Alt text

#MicroscopyMonday #science #biology #biomineralization #biomaterials #imaging #bioimaging #electronmicroscopy #mineral #collagen #apatite

www.nature.com/articles/s41...

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“Mineralized Tissue Biology” starter pack!

go.bsky.app/MasDNUf

#bone #teeth #mineralizedtissue #bonebiology #dental #enamel #fossil #archeology #paleontology #biomineralization #minerals #hardtissuebiology #imaging #liveimaging #microscopy #microCT #skeletalbiology #biomimicry #academicsky

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