#Blebbisomes

Imaging phosphoinositides during mitosis ! Cells stained against PI(4,5)P2 using recombinant biosensors (tinyurl.com/447fabz8)
PI(4,5)P2 is up regulated for cortex-membrane attachment. Also notice the membranes being shed and taken up by non-mitotic bystanders. #blebbisomes
@mag2art.bsky.social?

Environments can induce cell structural instability, resulting in cell fragments shedding that can actively migrate, as described by as #Blebbisomes, or, as some decided to go more Hollywood with the terms, #Zombosomes.

Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties - Nature Cell Biology Jeppesen, Sanchez et al. identify blebbisomes as large membrane-enclosed vesicles containing organelles and secreted by cells. Blebbisomes can both secrete and internalize exosomes and microvesicles.

☕Jeppesen, Sanchez, Burnette (@mag2art.bsky.social) & co identify #blebbisomes as large membrane-enclosed vesicles containing #organelles and secreted by cells. Blebbisomes can both secrete and internalize #exosomes and microvesicles. #CellBiology
bit.ly/3FBxqme

Have you read our March issue yet? We ‘re introducing #blebbisomes!

As usual, lots of interesting stuff on multiple fronts of #CellBiology, including #mitochondria, #MachineLearning, #organelles, #EmbryoPatterning & more!

www.nature.com/ncb/volumes/...

👋Our March issue's out!
Cover: Introducing #blebbisomes

👉🏼Review on #mitochondria #genetics
👉🏼Perspective on #MachineLearning and #SingleCell analyses
🔬 #organelles #autophagy #cancer #autophagy #endocytosis #EmbryoPatterning & more!
www.nature.com/ncb/volumes/...