Promoting osteoblast-mediated bone formation: a more promising approach for natural products to treat osteoporosis Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass, compromised bone microstructure, and an increased risk of fractures, …

Osteoporosis care must go beyond anti-resorption.

A CJNM review shows natural products can activate osteoblasts via RUNX2, WNT/β-catenin & PI3K/AKT signaling — supporting bone rebuilding.
🔗 Read the full study on ScienceDirect:

#Osteoporosis #BoneBiology #CJNM #DrugDiscovery

This review provides a comprehensive examination of AI's diverse applications in bone biology research, spanning from fundamental scientific investigations to potential therapeutic applications.
doi.org/10.59717/j.x...
#LifeSciences #artificialintelligence #bonebiology

Dr. Jacqueline Tabler | The Self-Organizing Bone Wave Underlying Skull Growth • scipod.global We typically take our skulls for granted, beyond their basic function in keeping our brain safe and sound within our head. When you look in the mirror, the shape of your skull, which forms the very st...

Dr Jacqueline Tabler's team reveals that skull bones grow through a self-organizing wave of differentiation, not cell migration. This biomechanical domino effect reshapes tissue from within. www.scipod.global/dr-jacquelin... #BoneBiology #SkullGrowth

PDLIM5, a protein that senses mechanical changes, promotes osteogenesis in adipose-derived stem cells by altering the cell’s internal structure (microfilaments). doi.org/10.1016/j.ge...
#StemCells #BoneBiology #PDLIM5 #Mechanotransduction

“Mineralized Tissue Biology” starter pack!

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#bone #teeth #mineralizedtissue #bonebiology #dental #enamel #fossil #archeology #paleontology #biomineralization #minerals #hardtissuebiology #imaging #liveimaging #microscopy #microCT #skeletalbiology #biomimicry #academicsky