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Boivin G, Farlay D, Khebbab MT, Jaurand X, Delmas PD, Meunier PJ. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Osteoporos Int. 2010 Apr;21(4):667-77. doi: 10.1007/s00198-009-1005-z. Epub 2009 Jul 14. PMID: 19597910.

Boivin G, Farlay D, Khebbab MT, Jaurand X, Delmas PD, Meunier PJ. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Osteoporos Int. 2010 Apr;21(4):667-77. doi: 10.1007/s00198-009-1005-z. Epub 2009 Jul 14. PMID: 19597910.

Strontium Ranelate Keeps Bones Strong: How It Supports Healthy Bone Formation in Osteoporotic Women! #BoneHealth #HealthyBones #Osteoarthritis #BoneResearch #ImagingInnovation #StrongBones #BoneWellness #BoneStrength #BoneRemodeling #EarlyDetection doi: 10.1007/s00198-009-1005-z

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T-scores help clinicians to interpret the measurements of bone mineral density (BMD) made using DEXA (Dual-Energy X-ray Absorptiometry) scans and find out whether patients have osteoporosis or other bone health issues. 

T-score compares a patient’s BMD measurement to the average BMD of a group of healthy young adults of the same sex and ethnic background and is calculated using the following equation:

T-score = (Patient's BMD - Mean BMD of Young Adult Reference Group) / (Standard Deviation of Young Adult Reference Group BMD)

Why it matters: T-scores indicate the patient’s risk of suffering a fragility fracture and their bone health status. A lower T-score means weaker bones and a higher risk of fractures.

T-score categories (as defined by the World Health Organisation) are normal: T-score ≥ -1.0: Osteopenia (low bone mass): T-score between -1.0 and -2.5;
Osteoporosis: T-score ≤ -2.5; Severe Osteoporosis: T-score ≤ -2.5 with fractures.

T-scores help clinicians to interpret the measurements of bone mineral density (BMD) made using DEXA (Dual-Energy X-ray Absorptiometry) scans and find out whether patients have osteoporosis or other bone health issues. T-score compares a patient’s BMD measurement to the average BMD of a group of healthy young adults of the same sex and ethnic background and is calculated using the following equation: T-score = (Patient's BMD - Mean BMD of Young Adult Reference Group) / (Standard Deviation of Young Adult Reference Group BMD) Why it matters: T-scores indicate the patient’s risk of suffering a fragility fracture and their bone health status. A lower T-score means weaker bones and a higher risk of fractures. T-score categories (as defined by the World Health Organisation) are normal: T-score ≥ -1.0: Osteopenia (low bone mass): T-score between -1.0 and -2.5; Osteoporosis: T-score ≤ -2.5; Severe Osteoporosis: T-score ≤ -2.5 with fractures.

What are the T-score values used in DEXA, and how are they calculated? #BoneHealth #JointCare #HealthyBones #Osteoarthritis #BoneResearch #JointHealth #ImagingInnovation
#StrongBones #BoneWellness #CartilageCare #BoneImaging #BoneStrength www.linkedin.com/in/tanuj-pur...

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Kuo J, Foster C, Shelton D. Particle disease on fluoride-18 (NaF) PET/CT imaging. J Radiol Case Rep. 2011;5(5):24-30. doi: 10.3941/jrcr.v5i5.697. Epub 2011 May 1. PMID: 22470793; PMCID: PMC3303443.

Kuo J, Foster C, Shelton D. Particle disease on fluoride-18 (NaF) PET/CT imaging. J Radiol Case Rep. 2011;5(5):24-30. doi: 10.3941/jrcr.v5i5.697. Epub 2011 May 1. PMID: 22470793; PMCID: PMC3303443.

Particle Disease on [18F]NaF PET-CT #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #BoneHealth #Osteoarthritis #BoneResearch #ImagingInnovation #BoneWellness #BoneImaging #BoneRemodeling doi: 10.3941/jrcr.v5i5.697

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Usmani S, Rasheed R, Al Kandari F. Textitis as Seen on 18F-NaF Imaging Using an Ultra-High-Resolution Positron Emission Mammography Scanner. J Nucl Med Technol. 2020 Jun;48(2):181-183. doi: 10.2967/jnmt.119.235986. Epub 2020 Feb 28. PMID: 32111663.

Usmani S, Rasheed R, Al Kandari F. Textitis as Seen on 18F-NaF Imaging Using an Ultra-High-Resolution Positron Emission Mammography Scanner. J Nucl Med Technol. 2020 Jun;48(2):181-183. doi: 10.2967/jnmt.119.235986. Epub 2020 Feb 28. PMID: 32111663.

Smartphone Overuse Strain Caught on [18F]NaF PET-CT #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #BoneHealth #JointCare #HealthyBones #BoneResearch #ImagingInnovation #BoneWellness #BoneImaging #BoneRemodeling #EarlyDetection doi: 10.2967/jnmt.119.235986

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Preview
Revision of the 1994 World Health Organization T-score definition of osteoporosis for use in older East Asian women and men to reconcile it with their lifetime risk of fragility fracture - Skeletal Ra... The 1994 WHO criterion of a T-score ≤ -2.5 for densitometric osteoporosis was chosen because it results in a prevalence commensurate with the observed lifetime risk of fragility fractures in Caucasian...

New T-score Guidelines for Osteoporosis in East Asians #BoneHealth #JointCare #HealthyBones #Osteoarthritis #BoneResearch #JointHealth #ImagingInnovation
#StrongBones #BoneWellness #CartilageCare #BoneImaging #BoneStrength #BoneRemodeling #EarlyDetection #ArthritisAwareness doi.org/10.1007/s002...

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Dweck MR, Jenkins WS, Vesey AT, Pringle MA, Chin CW, Malley TS, Cowie WJ, Tsampasian V, Richardson H, Fletcher A, Wallace WA, Pessotto R, van Beek EJ, Boon NA, Rudd JH, Newby DE. 18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis. Circ Cardiovasc Imaging. 2014 Mar;7(2):371-8. doi: 10.1161/CIRCIMAGING.113.001508. Epub 2014 Feb 7. PMID: 24508669.

Dweck MR, Jenkins WS, Vesey AT, Pringle MA, Chin CW, Malley TS, Cowie WJ, Tsampasian V, Richardson H, Fletcher A, Wallace WA, Pessotto R, van Beek EJ, Boon NA, Rudd JH, Newby DE. 18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis. Circ Cardiovasc Imaging. 2014 Mar;7(2):371-8. doi: 10.1161/CIRCIMAGING.113.001508. Epub 2014 Feb 7. PMID: 24508669.

[18F]NaF PET and Heart Valve Disease #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #StrongBones #BoneWellness #CartilageCare #EarlyDetection #ArthritisAwareness doi: 10.1161/CIRCIMAGING.113.001508

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PET/MRI of right knee of 36 year male having KL grade 0 showing high tracer uptake in medial central femur region (B) without any morphological changes in corresponding sagittal T2 SPIR image (A) also spatially correlated on fused PET/MRI image (C). Grade 1 osteophyte in lateral posterior tibial region in sagittal T1 TSE image (D) showing increased tracer uptake in PET (E) better appreciated on fused PET/MRI image (F). The T2 ∗ relaxometry cartigram overlayed on sagittal T2 SPIR image (G) showed mild changes in the cartilage of medial aspect of tibia (Green arrow for osteophytes and yellow arrow for region having intense tracer uptake without morphological changes). Physiological uptake was noted at tendon insertion sites on patella & tibial tuberosity.

Jena A, Goyal N, Vaishya R. 18F-NaF simultaneous PET/MRI in osteoarthritis: Initial observations with case illustration. J Clin Orthop Trauma. 2021 Aug 26;22:101569. doi: 10.1016/j.jcot.2021.101569. PMID: 34513587; PMCID: PMC8411223.

Keywords: Osteoarthritis (OA), PET/MRI, 18F–NaF, Standard uptake value (SUV)

PET/MRI of right knee of 36 year male having KL grade 0 showing high tracer uptake in medial central femur region (B) without any morphological changes in corresponding sagittal T2 SPIR image (A) also spatially correlated on fused PET/MRI image (C). Grade 1 osteophyte in lateral posterior tibial region in sagittal T1 TSE image (D) showing increased tracer uptake in PET (E) better appreciated on fused PET/MRI image (F). The T2 ∗ relaxometry cartigram overlayed on sagittal T2 SPIR image (G) showed mild changes in the cartilage of medial aspect of tibia (Green arrow for osteophytes and yellow arrow for region having intense tracer uptake without morphological changes). Physiological uptake was noted at tendon insertion sites on patella & tibial tuberosity. Jena A, Goyal N, Vaishya R. 18F-NaF simultaneous PET/MRI in osteoarthritis: Initial observations with case illustration. J Clin Orthop Trauma. 2021 Aug 26;22:101569. doi: 10.1016/j.jcot.2021.101569. PMID: 34513587; PMCID: PMC8411223. Keywords: Osteoarthritis (OA), PET/MRI, 18F–NaF, Standard uptake value (SUV)

[18F]NaF PET in osteoarthritis #18FNaF #BoneHealth #JointCare #HealthyBones #Osteoarthritis #BoneResearch #JointHealth #ImagingInnovation #StrongBones #BoneWellness #CartilageCare #BoneImaging #BoneRemodeling #EarlyDetection #ArthritisAwareness doi: 10.1016/j.jcot.2021.101569

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