Congrats to first author, Seher Alam, and thanks to all students and collaborators!

We're grateful for support from @scilifelab.se, @novonordisk.bsky.social, and Cancer Research KI, as well as fellowships from Barncancerfonden and Cancerfonden.

Fin

#TPD #PROTAC #CeTEAM #NUDT5

This direct-to-cell CeTEAM selectivity assay should facilitate the discovery of truly selective PARPi (as well as triaging of PARP trapping tendencies!).

Congrats to all authors, esp. Maria Pires and Seher Alam!

Funding: Cancerfonden and Barncancerfonden 🙏

#PARP
#selectivity
#CeTEAM

3/3

Very happy to have been able to contribute to this amazing story! Check out the paper at Nature Communications and the 🧵 by @nckvalerie.bsky.social below 👇. We believe #CeTeam will be an invaluable tool for #drugdiscovery and #targetvalidation in #cells

🔗: www.nature.com/articles/s41...

Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM - Nature Communications Cellular target engagement technologies enable quantification of intracellular drug binding, but the simultaneous assessment of drug-associated phenotypes is challenging. Here, the authors develop CeT...

Good timing for a first Bluesky post! 🦋

I'm thrilled to share that our BioRxiv preprint on #CeTEAM has now been published in Nature Communications!

🔗: www.nature.com/articles/s41...

A short 🧵 1/x 👇