Application of PROTACs in target identification and validation
www.scienceopen.com/hosted-docum...
#PROTAC #TargetIdentification #TargetValidation #DrugDiscovery #ChemicalBiology

🔬February New Releases
🚀1,000+ new molecules for #Oncology, #Neurology, #Immunology, #Cardiovascular studies.
Key targets: #Hsp70, #MDM2, #EGFR/HER2, #M4, #Keap1-Nrf2, #IP6K. Includes first-in-class & clinical-stage compounds to boost #DrugDiscovery & #TargetValidation.

🚨 Upcoming SMR drug discovery event! 📣📣📣

🎯 Target ID and validation
🗓️ Oct 24, 2025
📍 Cambridge, UK
🔗 www.smr.org.uk/Meetings/202...

Please share widely!

#DrugDiscovery #TargetValidation #Pharma #Biotech #LifeSciences #SMR

🧪 As a complement to CCT251545 and CCT251921, the study also highlights MSC2530818 as a valuable orthogonal CDK8/19 probe, further strengthening confidence in on-target effects and enabling robust mechanistic studies.
#ChemicalProbes #CDK8 #TargetValidation

Very happy to have been able to contribute to this amazing story! Check out the paper at Nature Communications and the 🧵 by @nckvalerie.bsky.social below 👇. We believe #CeTeam will be an invaluable tool for #drugdiscovery and #targetvalidation in #cells

🔗: www.nature.com/articles/s41...