New study maps cellular mechanisms driving fibrosis in Crohn's Disease Researchers at the Earlham Institute, the University of Edinburgh and Heriot-Watt University have analysed gut cells to understand the drivers behind fibrosis (scarring), a common complication in…

📄 Researchers studying fibrosis in Crohn's disease have found that immune cells and endothelial cells localise around scar tissue within the submucosa, a layer of tissue beneath the inner lining of the bowel.

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#CellAtlas #scRNAseq

Broad collaboration produces high-resolution atlas of developing human brain Johns Hopkins researchers have enhanced a cellular road map of how the brain forms and adapts early in life

A Map of Becoming: The Most Detailed Atlas of the Growing Human Brain Yet hub.jhu.edu/2026/03/26/h... #HumanBrain
#ScienceNews #BRAINInitiative #CellAtlas #Genomics
#Neurodevelopment #FutureOfMedicine #JohnsHopkins #Research

New study maps cellular mechanisms driving fibrosis in Crohn's Disease Researchers at the Earlham Institute, the University of Edinburgh and Heriot-Watt University have analysed gut cells to understand the drivers behind fibrosis (scarring), a common complication in…

💬 “The power of #singlecell transcriptomics coupled with computational analysis lies in its ability to reveal cellular interactions that aren’t discernible otherwise." - Prof Irene Papatheodorou

Scientists working on a Gut #CellAtlas have analysed gut cells to study the drivers behind fibrosis.

New study maps cellular mechanisms driving fibrosis in Crohn's Disease Researchers at the Earlham Institute, the University of Edinburgh and Heriot-Watt University have analysed gut cells to understand the drivers behind fibrosis (scarring), a common complication in Crohn’s Disease affecting 10-20% of patients.

🆕 New Study: Scientists working on a Gut Cell Atlas have conducted #singlecell #RNAseq on intestinal cells, discovering clusters of immune and endothelial cells localise around scar tissue in the submucosa. 🧬💻

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@uoe-igc.bsky.social @helmsleytrust.bsky.social

#CellAtlas #scRNAseq

Helmholtz Munich Launches Collaboration on AI-Driven Kidney Disease Research

Mapping the Kidney at Single-Cell Resolution 🤖

#HelmholtzMunich and #Novartis Biomedical Research are launching a four-year collaboration to advance #KidneyDisease research with #AI-driven modeling, #VirtualCell simulations, & large-scale perturbation analysis.

👉 t1p.de/yf554

#CellAtlas

🧬 U of Tokyo built a 3D map of EVERY SINGLE CELL across all organs — the CUBIC Organ/Body Atlas.
Could revolutionize drug development, cancer research, and how we understand organ function.
#CellAtlas #SpatialBiology #CUBIC #BioTech

New perspectives on human health and biodiversity using cell atlases Scientists have been characterising and classifying cells in increasing detail for centuries. From the development of new disease treatments to the genetic engineering of crops designed to withstand…

Decoding Phenotypes at the Cell Type Level 🔬🧬💻

Later this month catch Prof Irene Papatheodorou, at the London Festival of Genomics and Biodata discussing her latest research in #cellular #genomics and international #cellatlas projects. #FOG2026

Discover more about her research 👇

We’re excited to announce the winners of the Human Cell Atlasing Grant Program! Each winner will receive one free MERSCOPE Ultra™ slide run using a MERFISH 2.0™ gene panel. Congrats to the winners! We can’t wait to follow your progress. #CellAtlas

Sea urchins don’t have a brain - so they became one Young sea urchins spread neuron-rich tissue across their bodies. A new atlas shows complex neural and light sensing networks.

"As similar atlases emerge across other echinoderms, scientists can finally test whether this whole-body brain is a common strategy or a sea urchin specialty. The study is published in the journal Science Advances."
🌊🦔🧠 #SeaUrchins #Neurology #CellAtlas #Biology #Oceans #Nature

Fibroblast specialisation across microanatomy in a single-cell atlas of healthy human Achilles tendon Tendons are transitional tissues linking muscle to bone, enabling locomotion and fine motor control. The cellular biology across the Achilles tendon unit is poorly understood, yet critical for interpr...

We’ve mapped the Achilles tendon at single-cell resolution 🧬 — revealing 6 fibroblast types with distinct roles across muscle–tendon zones. A new atlas for understanding injury + repair.

Find our more in our new preprint www.biorxiv.org/content/10.1...

#Tendon #CellAtlas #SpatialTranscriptomics

New perspectives on human health and biodiversity using cell atlases Scientists have been characterising and classifying cells in increasing detail for centuries. From the development of new disease treatments to the genetic engineering of crops designed to withstand…

Scientists at the Earlham Institute are developing tools to support the #singlecell community improve #metadata standards for the #FAIR sharing of data, and the creation of cell atlases. 🧬💻

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#cellatlas #cellbiology #FAIRdata

New perspectives on human health and biodiversity using cell atlases Scientists have been characterising and classifying cells in increasing detail for centuries. From the development of new disease treatments to the genetic engineering of crops designed to withstand…

In a recent feature, Prof Irene Papatheodorou, Head of Data Science at the Earlham Institute and member of the BCA project discussed her thoughts on the potential impacts of global #cellatlas projects, and well as #computational challenges currently facing the community:

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The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution - Nature The Biodiversity Cell Atlas aims to create comprehensive single-cell molecular atlases across the eukaryotic tree of life, which will be phylogenetically informed, rely on high-quality genomes and…

🆕 New in @nature.com, scientists introduce the #Biodiversity #CellAtlas - creating comprehensive #singlecell molecular atlases across the eukaryotic tree of life.

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@arnausebe.bsky.social

Creating a map of every living thing, cell by cell An ambitious and revolutionary initiative aims to map every cell of all eukaryotic life on Earth. The result will be a Biodiversity Cell Atlas, which will reveal nature's secrets and help inform conservation efforts at a level that is not currently possible.

✨ Scientists embark on a quest to map *every* cell of life! 🌍 The Biodiversity Cell Atlas will unlock nature’s hidden secrets & revolutionize conservation. 🔬 #CellAtlas

Source: https://phys.org/news/2025-09-cell.html

New perspectives on human health and biodiversity using cell atlases Scientists have been characterising and classifying cells in increasing detail for centuries. From the development of new disease treatments to the genetic engineering of crops designed to withstand…

💬 “Our recent work in #Lichen has been particularly fascinating, to see how #cells from unicellular organisms interact and specialise to make up a multicellular organism.”

In a new article, we chat to Prof Irene Papatheodorou her group's work on global #cellatlas projects.

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🧬💻

New perspectives on human health and biodiversity using cell atlases Scientists have been characterising and classifying cells in increasing detail for centuries. From the development of new disease treatments to the genetic engineering of crops designed to withstand…

Scientists are creating tools to enable the #singlecell community improve metadata standards for the #FAIR sharing of data and the creation of cell atlases. 🧬💻

buff.ly/eFNeo6k

#cellatlas #cellbiology #FAIRdata

New perspectives on human health and biodiversity using cell atlases Scientists have been characterising and classifying cells in increasing detail for centuries. From the development of new disease treatments to the genetic engineering of crops designed to withstand…

💬 “What really fascinates me is the diversity of different cellular interactions, the robustness and plasticity of cells that is being uncovered by generating and studying these atlases." - Prof Irene Papatheodorou, Head of Data Science

👉 buff.ly/eFNeo6k

#cellular #genomics #cellatlas

🆕 The #cellatlas community holds the potential to unlock critical new insights to tackle urgent global challenges, but bringing together vast #datasets and multiple studies from across the globe come with inherent challenges.

🌏🌱🧬💻🔬

#cellular #genomics

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Macro photograph of common orange lichen, a bright mustard colour, on a branch.

Dr Ellen Cameron presenting her work on the Lichen Cell Atlas at our recent science symposium.

Unicellular green algae, the algal partner of common orange lichen.

🆕 What's so special about #lichen?

Researchers in the Papatheodorou Group at Earlham Institute are building a #cellatlas to explore the symbiotic relationships of the algae and fungal partners in lichen.

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What does it take to build a T cell atlas? We break it down in our latest review.
👉 Now out in Immunology & Cell Biology: onlinelibrary.wiley.com/doi/10.1111/...

#Tcells #SingleCell #Immunology #ReviewArticle #CellAtlas
@turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi

Both handle massive, complex data — but with different missions. One builds apps. The other builds cellular maps of tissues.

#spatiotemporalomics #singlecell #computationalbiology #systemsbiology #multiomics #cellatlas #spatialomics #scRNAseq #genomics

Characterizing molecular programs guiding #CardioPulmonary maturation through integration of #SpatialTranscriptomics with #Computational #CellTrajectory analysis and #TranscriptionalProfiling doi.org/10.1016/j.ce... #CellAtlas #TranslationalScience

Prof Irene Papatheodorou, Head of Data Science at the Earlham Institute

Today at #AGBTAg meeting, Prof Irene Papatheodorou, Head of #DataScience at the Earlham Institute, is presenting her work generating insights from cross-species international #cellatlas projects.

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AGBTAg Meeting 2025 Prof Irene Papatheodorou is Head of Data Science at the Earlham Institute where she leads a group of skilled data-led scientists.

Catch Prof Irene Papatheodorou, Head of #DataScience at the Earlham Institute at #AGBTAg.

Irene will discuss her work on international #cellatlas projects, and this Sunday take part in a workshop on community adoption of standardised workflows for integrated #singlecell analyses.

Prof Irene Papatheodorou, Head of Data Science at the Earlham Institute will be presenting a talk at AGBT Agricultural Meeting titled: "insights from cross-species comparisons of cell atlases". Wednesday 2 April from 14.00 - 14.30.

Prof Irene Papatheodorou, Head of #DataScience at the Earlham Institute will be attending #AGBTAg later this month. Irene will discuss her work on international #cellatlas projects, and take part in a workshop on community adoption of standardised workflows for integrated #singlecell analyses.

Don't miss your chance to shine at Single Cell Biology! Submit your abstract for a short talk by March 11, 11:59pm MST. Seize the opportunity now: hubs.la/Q03bmfh00

#KSSingleCell25 #singlecell #singlecellbiology #singlecellanalysis #cellatlas #tissueatlas #spatialomics

Submit your abstracts or scholarship applications by Feb. 11 (11:59pm MST) to present alongside experts like Matthew F. Krummel & Gordana V. Vunjak-Novakovic. See you in May! keysym.us/KSSingleCell25

#KSSingleCell25 #singlecellbiology #singlecellanalysis #cellatlas #tissueatlas #spatialomics

Cross-species cell atlases for regeneration

Applications close soon for a Marie Skłodowska-Curie Doctoral #PhD project with Prof Irene Papatheodorou, developing comprehensive cell atlases of regeneration in three different species, #zebrafish, mouse and axolotl.
#singlecell #cellatlas @daniorecode.bsky.social

Cross-species cell atlases for regeneration

Applications are open for a Marie Skłodowska-Curie Doctoral #PhD project with Prof Irene Papatheodorou, developing comprehensive cell atlases of regeneration in three different species, zebrafish, mouse and axolotl. #singlecell #cellatlas @daniorecode.bsky.social

📅 Apply by: 16 January 2025

Postdoctoral Research Scientist

VACANCY: We're looking for a #postdoc with experience in #singlecell and #spatialtranscriptomics data, and an understanding of statistics in biology, to join the group of Prof Irene Papatheodorou, as part of the #Gut #CellAtlas programme.

📅 Apply by: 06 January 2025
📄 Contract length: 24 months