#Condensin II collaborates with #cohesin to establish and maintain #interphase #chromosome territories, say Takao Ono, Tatsuya Hirano (Riken) and colleagues: rupress.org/jcb/article/...

#CellCycle #Biochemistry #Chromatin

In @jcb.org, Takao Ono, Tatsuya Hirano et al. show that #condensin II collaborates with #cohesin to establish and maintain #chromosome territories, revealing a cooperative mechanism supporting large-scale #genome organization in #interphase. rupress.org/jcb/article/...

#CellCycle #Chromatin

Takao Ono, Tatsuya Hirano et al. show that #condensin II collaborates with #cohesin to establish and maintain #chromosome territories, revealing a cooperative mechanism supporting large-scale #genome organization in #interphase. rupress.org/jcb/article/...

#CellCycle #Biochemistry #Chromatin

Chromosome Shapes Are Dynamic, Not Fixed X Structures, Study Finds

Live‑cell imaging shows chromosomes continually shorten and thicken during mitosis; short arms reach a compact shape in 30 min while longer arms keep shrinking for six hours. Read more: getnews.me/chromosome-shapes-are-dy... #chromosomes #condensin

Spontaneously directed loop extrusion in SMC complexes emerges from broken detailed balance and anisotropic DNA search Abstract. DNA loop formation by structural maintenance of chromosome (SMC) proteins, including cohesin, condensin, and the SMC5/6 complex, plays a pivotal

⭐NAR Breakthrough!⭐
Bonato et al. propose a model for how the yeast #condensin SMC complex drives persistent #DNAloopextrusion, using #atomicforcemicroscopy and #moleculardynamics.

Read the full article here: doi.org/10.1093/nar/...
#NARBreakthrough #SMC #biophysics #genomefolding #yeast

By demonstrating that condensin I-DC has an active ATPase that's required for dosage compensation, we hopefully apply these findings to other scenarios where condensins mediate gene regulation

#condensin #generegulation #chromatin #celegans 🪱

Condensin IDC has a Functional ATPase That is Required for X-Chromosome Dosage Compensation in C. elegans Dosage compensation (DC) in C. elegans utilizes a condensin complex that resembles mitotic condensins, but differs by one subunit, DPY-27. DPY-27 replaces SMC-4, one of the Structural Maintenance of C...

The preprint of my main thesis work is live! #condensin #chromatin #generegulation #celegans 🪱

www.biorxiv.org/content/10.1...

Shaping up genomes: Prokaryotic roots and eukaryotic diversification of SMC complexes bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Online: our evolutionary interrogation of eukaryotic Structural Maintenance of Chromosomes (SMC) complexes @maxraas.bsky.social @eelcotromer.bsky.social @lauraeme.bsky.social #SMCcomplexes #eukaryogenesis #LECA #condensin #cohesin #evolutionarycellbiology #chromatin 🧵(1/6) doi.org/10.1101/2024...