#SingleCellRNAseq #PseudotimeAnalysis #DiabetesResearch #BetaCellHeterogeneity #GenomicsPublished by: Kaixuan Bao, Zhicheng Cui, Hui Wang, et al.📅 Publis

Polygenic risk influences who crosses key diagnostic HbA1c thresholds in GCK-MODY. Monogenic + polygenic risk both matter #MODY #DiabetesResearch #PrecisionMedicine

As a medical school professor, I teach that red blood cells carry oxygen. But a breakthrough from Gladstone Institutes just revealed they do something ... www.sciencedaily.com/releases/2026/02/2602210...

#DiabetesResearch #MetabolicHealth #Longevity #BloodSugar #HealthLongevitySecrets

New data on #exercise timing for people with #Type1Diabetes: change in blood glucose during resistance exercise is more consistent when exercise is performed in the morning while fasted than in the afternoon after eating #T1D #DiabetesResearch

Walnut Extract May Help Control Blood Sugar Naturally, New Study Finds Type 2 diabetes gradually damages the pancreas, where insulin producing beta cells struggle under oxidative stress, chronic inflammation, and impaired signaling. As blood sugar levels rise, standard treatments like Metformin or insulin therapy help manage symptoms, yet many patients seek natural ways to improve insulin sensitivity. One promising candidate is Juglans regia, widely known as the walnut tree. Used in traditional medicine for centuries, its leaves, bark, and nuts contain bioactive compounds now gaining scientific attention.

Walnut extract may improve insulin sensitivity and support blood sugar control in type 2 diabetes, new research suggests.
#DiabetesResearch #BloodSugarControl #NaturalHealth

Interesting new data on timing of eating and how this affects glucose management in #GDM #Pregnancy #DiabetesResearch

Beta cell glucose sensitivity identifies clinical response to disease-modifying therapies initiated at the onset of stage 3 #T1D #DiabetesResearch

Beta cell glucose sensitivity identifies clinical response to disease-modifying therapies initiated at stage 3 type 1 diabetes onset - Diabetologia Aims/hypothesis At present, no disease-modifying therapies are available for individuals who have been newly diagnosed with type 1 diabetes, despite promising results from decades of clinical trials i...

Beta cell glucose sensitivity in association with clinical and demographic parameters can be leveraged to identify drug responders and inform clinical trials performed at stage 3 type 1 diabetes onset. #T1D #DiabetesResearch link.springer.com/article/10.1... 🔓

Graphic with a blue gradient background announcing “Call for nominations - EASD Honorary Membership 2026.” The text invites members to submit nominations for lifetime EASD Honorary Membership. The EASD logo appears at the bottom left, and the website “easd.org” is shown at the bottom right, with circular design elements on the right side of the image.

🚨 Final Call! EASD #Honorary Membership Nominations close in 4 Days. Recognise a pioneer who's dedicated their career to advancing #diabetesresearch. Nominate them today!

📅Nominations close: 27 March 2026 |🕛 23:59 CET

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Don't miss this opportunity!

Early meal timing improves nocturnal glucose in pregnancies complicated by gestational diabetes - Diabetologia Aims/hypothesis Gestational diabetes (GDM) results in adverse outcomes for the pregnant individual and neonate. Lifestyle modifications are first-line interventions used to achieve pregnancy-specific ...

For gestational diabetes, eating your first meal earlier in the morning was linked to better overnight glucose management. A good reminder that it’s not just what you eat—when you eat matters too #GDM #DiabetesResearch link.springer.com/article/10.1... 🔓

Mechanistic study showing that ER–mitochondria calcium coupling regulates nutrient-induced GLP-1 secretion #DiabetesResearch

A polygenic risk score for #T1D provides enhanced ability to predict #diabetes risk in non-European populations #DiabetesResearch #Ancestry #Genetics

Development and validation of a trans-ancestry polygenic risk score for type 1 diabetes - Diabetologia Aims/hypothesis The high heritability of type 1 diabetes has enabled the development of polygenic risk scores (PRSs) as disease risk screening tools. PRSs can identify individuals at the highest genet...

A new trans-ancestry polygenic risk score for type 1 diabetes shows enhanced ability to predict the disease in non-European populations #T1D #DiabetesResearch link.springer.com/article/10.1... 🔓

The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation - Diab... Aims/hypothesis Growing evidence implicates gut microbiota-derived metabolites in metabolic homeostasis. Indole, a microbial tryptophan metabolite, has been reported to enhance glucagon-like peptide-1...

Could the gut and its bacteria hold the key to new diabetes therapies? A new study shows that the microbial metabolite indole boosts gut hormone release & improves blood sugar control. #T2D #GutMicrobiome #DiabetesResearch link.springer.com/article/10.1... 🔓

Join the 13th International Conference on Endocrinology & Diabetes
📅 April 06–08, 2026
📍 Rome, Italy
Virtual Participation Available
Registration: $149 USD
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#endocrinology #diabetesresearch #medicalconference

A review covering the atypical forms of diabetes that are common in African populations - there are four main diabetes subtypes with implications for diagnosis, treatment and equity in care across Africa #DiabetesResearch

A systematic analysis of loss-of-function variants in MODY-related genes expands our understanding of variants that cause #MODY #DiabetesResearch #Genetics

Systematic analysis of loss-of-function variants across MODY genes demonstrates gene-specific effects and expands the spectrum of INS variants causing MODY - Diabetologia Aims/hypothesis Accurate interpretation of loss-of-function (LOF) variants in MODY genes is essential for diagnosis but remains challenging, particularly for variants that are predicted to escape nons...

Systematic analysis of loss-of-function variants across MODY genes demonstrates gene-specific effects and expands the spectrum of INS variants causing MODY #MODY #Insulin #Genetics #DiabetesResearch link.springer.com/article/10.1... 🔓

A diabetes-induced change of MDM2 SNP309T→G contributes to aberrant retinal angiogenesis - Diabetologia Aims/hypothesis The 309G SNP in the second promoter of the gene encoding mouse double minute 2 (MDM2) has been implicated in multiple human diseases. The aims of this study were to determine whether M...

MDM2 SNP309G is linked to proliferative diabetic retinopathy and promotes pathological retinal angiogenesis in a mouse model of oxygen-induced retinopathy
#DiabetesResearch #DiabeticRetinopathy link.springer.com/article/10.1...

Zhittya x Wayne Allyn Root Zhittya Genesis Medicine (zgm.care) pioneers innovative clinical trials for Parkinson’s Disease, Heart Disease, Type-2 Diabetes and more. Offering hope through cutting-edge regenerative medicine. Expl...

🌟 Possible Breakthrough in Diabetes & Parkinson’s Research 🌟
If you want to learn more about the work they’re doing, you can visit:

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#DiabetesResearch
#DiabetesAwareness
#Type2Diabetes
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Timo Müller Receives the 2026 ADA Outstanding Scientific Achievement Award

Timo Müller Receives the #ADA 2026 Outstanding Scientific Achievement Award👏

Prof. Timo Müller, #HelmholtzMunich, is a global leader in #MetabolicResearch. His research continues to open new avenues for innovative therapies against metabolic diseases.

👉 t1p.de/qq5nl

#DiabetesResearch

GlucoseGo: a simple tool to predict hypoglycaemia during exercise in type 1 diabetes - Diabetologia Aims/hypothesis This study aimed to develop an accessible tool, derived using machine learning, to predict hypoglycaemia risk at the start of exercise and to provide clear, rapid risk assessment to su...

New data on #GlucoseGo, a simple tool developed with machine learning, which predicts hypoglycaemia risk in #Type1Diabetes, just using starting glucose & exercise duration. Supporting safer workouts! 🏃‍♀️💡🩺 #DiabetesResearch #T1DExercise link.springer.com/article/10.1... 🔓

Maternal pre-pregnancy BMI defines distinct fetoplacental endothelial phenotypes - precision stratification in gestational diabetes may refine risk assessment #DiabetesResearch #GDM #Pregnancy

RCT data showing that canagliflozin reduces myocardial fibrosis in high-risk #T2DM, providing imaging evidence for its cardioprotection #DiabetesResearch #SGLT2i

Up front in the March issue of @diabetologiajnl.bsky.social #editorspicks #diabetesresearch

Up front in the March issue of @diabetologiajnl.bsky.social #editorspicks #diabetesresearch

TALK-2, a K+ channel associated with diabetes, controls human beta cell ER Ca2+ handling, promoting basal insulin release and limiting glucose-stimulated insulin secretion #BetaCells #Islets #DiabetesResearch

The diabetes-associated K+ channel TALK-2 controls human beta cell endoplasmic reticulum Ca2+ handling, which promotes basal insulin release and limits glucose-stimulated insulin secretion - Diabetolo... Aims/hypothesis The two-pore domain K+ channel TWIK1-related alkalinisation-activated K+ channel 2 (TALK-2) is encoded by KCNK17, which is one of the most abundant beta cell K+ channel transcripts tha...

The diabetes-associated K+ channel TALK-2 controls human beta cell endoplasmic reticulum Ca2+ handling, which promotes basal insulin release and limits glucose-stimulated insulin secretion #DiabetesResearch #BetaCells #Islets link.springer.com/article/10.1... 🔓

Canagliflozin attenuates CMR-quantified myocardial fibrosis in individuals with type 2 diabetes mellitus at high cardiovascular risk: a randomised open-label controlled trial - Diabetologia Aims/hypothesis We aimed to investigate canagliflozin’s effects on myocardial fibrosis, cardiac structure and function, and microcirculation in high-cardiovascular-risk type 2 diabetes mellitus throug...

Novel RCT: Canagliflozin reduces myocardial fibrosis (by CMR) in high-risk #T2DM, providing imaging evidence for its cardioprotection. A mechanism beyond glycaemic management. #SGLT2i #CardioDiabetes #HeartFailure #DiabetesResearch link.springer.com/article/10.1... 🔓

Up front in the March issue of Diabetologia #EditorsPicks #DiabetesResearch