Happy to announce the next RE-Place Educational Webinar 🤩

Topic: 'Human-based #invitro and #exvivo models as alternatives to animal testing: From bone development to #immunotoxicity'

📅 30 April |⌚ 4 to 5 pm |📍Online via Webex

Register now: lnkd.in/eZdR9zdU

A set of rules that govern disease-causing infections, and include the isolation of a #pathogen from a diseased organism, culture of the pathogen #ExVivo, successful infection of healthy organisms with the same pathogen, and finally, reisolation of the same pathogen from the newly diseased organism.

Precision Cut Liver Slices for Ex Vivo Research | Campden Instruments Precision-Cut Liver Slices (PCLS) are emerging as a gold-standard ex vivo model for liver research, offering a structurally and functionally intact hepatic microenvironment.

Optimized vibratome settings are key to reproducible, viable PCLS.

See how @campdeninstruments.bsky.social vibrating microtomes support high-quality PCLS prep across diverse research applications:
campdeninstruments.com/pages/precis...

#LiverResearch #PCLS #ExVivo #Hepatology #Toxicology

Precision Cut Lung Slices (PCLS) for Ex Vivo Research | Campden Instruments Discover precision cut lung slices (PCLS) for toxicology, immunology, and drug development. Improve reproducibility with Campden?s lung tissue slicing systems.

Advantages of PCLS
1. Preservation of lung architecture
2. Highly reproducible experimental results
3. Multifunctional applications for imaging, pharmacology, and toxicity testing

🔬 Learn more about #PCLS for #exvivo studies
campdeninstruments.com/pages/precis...

Six of us from our Translational Oncology Group are in there somewhere ☺️. Enjoyable day at the Inventia Life Science Headquarters in Sydney for the first RASTRUM User Group Meeting. #3Dbioprinting #3Dmodelling #invasion #cancermodelling #exvivo #drugtesting #translationalscience #precisionmedicine

Navigating the Future of Preclinical Research: Aligning with the FDA’s Roadmap on Animal Testing The FDA's recent Roadmap to Reducing Animal Testing in Preclinical Safety Studies marks a pivotal shift toward the adoption of innovative, human-relevant methodologies commonly known as New Approach M...

The FDA is charting a path to reduce animal testing in preclinical studies, but is the research world ready for it? Check out our recent blog here:
hubs.ly/Q03l_2x20
#PreclinicalResearch #FDA #AnimalModels #ResearchInnovation #exvivo #Invitro #NAMs

Last day at #AACR and Sakthi Srinivasan, PhD and Helena Laven will present exciting data from Immuneed 🌟🥳 www.immuneed.com

lnkd.in/dxAZe5mk

#oligotherapeutics #drugscreening #safety #modeofaction #therapeutics #drugdevelopment #nonclinical #preclinical #clinical #exvivo #human #3R

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My very christmassy tumour coculture spheriod on Santa Sleigh!
Feliz Navidad!
#exvivo #EVIDENT #uos #3dcoculture #spheroid #fluorescencemicroscopy #CancerResearch #phdlife #Commonwealthscholar @sheffielduni.bsky.social

Check out this human-relevant research #funding opportunity from #NIAID! Submit your applications to use #organchips, #organoids, #bioprinting, and #exvivo models for studying human #radiation exposure and developing medical countermeasures.
grants.nih.gov/grants/guide...

Images of lymph node tissue labeled by immunofluorescence. Breast cancer cell line (BRPKp110) in teal; B cells in green (CD19), lymphatics in purple (Lyve-1), stromal cells in grey (podoplanin).

New preprint! Katerina Morgaenko showed that #ExVivo lymph node tissue supports cancer cell invasion. Ex vivo = mix/match cancer cells and tissue to study chemotactic mechanisms without lymphatic entry barriers. #CancerImmunology #ImmunoEngineering

www.biorxiv.org/content/10.1...