Jesús García-Castro, MD was awarded the 2026 Next Generation Research Grant in Frontotemporal Dementia. Dr. García-Castro will combine blood testing and MRI brain scans to develop improved diagnostic methods for detecting subtypes of FTD called progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Currently, both variants are difficult to diagnose in early stages because of symptoms that resemble other brain conditions. This research is co-funded with The Holloway Family Fund of the Association for Frontotemporal Degeneration.

Jesús García-Castro, MD was awarded the 2026 Next Generation Research Grant in #FrontotemporalDementia.

Institution: Institut de Recerca Sant Pau
This research is co-funded with @theaftd.bsky.social.

More ➡️ buff.ly/gGXsiuD
#FTDResearch

Researcher Feature: Frontotemporal Degeneration Research. Meet Janani Parameswaran, PhD an American Brain Foundation 2025 Next Generation Research Grantee investigating Frontotemporal Degeneration. Dr. Parameswaran is studying a protein called TMEM106B, which forms clusters in some cases of ALS and frontotemporal degeneration (FTD). She will investigate how these clusters contribute to brain cell damage and affect gene activity. Her findings could help uncover new treatment targets.

Meet 2025 Next Gen. Researcher Janani Parameswaran, PhD. She is studying the role of protein TMEM106B in C9orf72, a genetic form of frontotemporal dementia (FTD). Funded with @AFTDHope and @AANmember. #FTDResearch

🧠 Learn more about Dr. Parameswaran's research: buff.ly/dL1vTM8

You Joined. Now What? Five Small Ways to Stay Research Ready - FTD Disorders Registry You joined the FTD Disorders Registry. Now learn five simple ways to stay research ready and strengthen the future of FTD research.

You joined the FTD Disorders Registry. Now what?

Update your info. Enroll in the Registry Research Study. Complete surveys.

FTD is rare. Every participant matters. Numbers have power.

Learn more: ftdregistry.org/press/you-jo...

#endFTD #FTDresearch

Strengthening FTD Research with CureGRN - FTD Disorders Registry Progress toward an FTD cure depends on communities and researchers working together.

Progress toward an FTD cure depends on communities and researchers working together.

Learn how the FTD Disorders Registry and the Cure GRN-FTD community are helping advance research and future clinical trials: ftdregistry.org/press/streng...

#endFTD #CureGRN #FTDresearch

2025 was a year of momentum for the FTD Disorders Registry, with a 97% increase in new accounts. Learn more about the year’s growth and impact: ftdregistry.org/press/a-year...
#endFTD #FTDresearch

The Road Ahead: How Registry Data Can Drive Breakthroughs - FTD Disorders Registry Progress is possible. See how Registry data can unlock breakthroughs in FTD research just as new treatments are showing progress in other neurological disorders.

Registry data helps researchers spot patterns, shape better studies, and move us closer to treatments for FTD. Every participant makes a difference.

Read more: ftdregistry.org/press/the-ro...

#FTD #EndFTD #FTDResearch

During World FTD Awareness Week, we recognize the challenges care partners face. The daily demands of FTD can make research participation difficult, yet their voices are essential to progress.

Learn more: ftdregistry.org/press/how-ca...

#WorldFTDAwarenessWeek #endFTD #FTDResearch #FTDAwareness

FTD can steal your words, your connection, your voice. Join the FTD Disorders Registry to help researchers find treatments and a cure. www.FTDRegistry.org

#endFTD #FTDAwareness #WorldFTDAwarenessWeek #FTDResearch

FTD disorders can make someone seem like a stranger to their loved ones.

Registry data show three of the most distressing symptoms are impaired judgment, personality changes, and mood changes. www.ftdregistry.org

#WorldFTDAwarenessWeek #EndFTD #FTDAwareness #FTDResearch

From Surveys to Science: How Registry Data Becomes Research - FTD Disorders Registry Every survey response in the Registry Research Study helps turn lived experience into research data that drives discovery.

World FTD Awareness Week starts with action!

See how survey responses from the Registry Research Study become powerful data that drives FTD disorders research.

Read more: ftdregistry.org/press/from-s...

#endFTD #FTDAwareness #FTDResearch

Memory isn’t usually the first thing to change in FTD.

Registry data shows the most common early symptoms are:
• Language challenges
• Cognitive changes
• Mood changes

Raising awareness helps speed diagnosis & research.
www.FTDregistry.org

#EndFTD #FTDAwareness #FTDResearch

ORION Trial Ends, Reinforcing the Need for Continued FTD Research - FTD Disorders Registry Research is our roadmap to breakthroughs, and sometimes setbacks are the fuel that drive us forward.

Amylyx’s ORION trial in PSP has ended after not meeting its goals. While the news is disappointing, every study adds knowledge that guides future research.

Read more: ftdregistry.org/press/orion-...

#endFTD #FTDresearch

Thank you, #AAIC2025! We loved connecting with researchers, clinicians & advocates at our booth. Your curiosity and commitment to advancing #FTD understanding inspire us. Let’s keep moving toward earlier diagnosis and better care. #FTDRegistry #FTDResearch #EndFTD

We’re grateful to be able to share the FTD Disorders Registry's work at #AAIC2025! Stop by during today’s poster sessions to connect with Registry Director Carrie Milliard. We’re always eager to exchange ideas and insights.

#endFTD #FTD #FTDResearch

Great to see the team behind the Progranulin Information Navigator by the Bluefield Project at #AAIC2025! This resource raises awareness of GRN-specific trials & improves access to genetic testing & counseling. Bluefield is also a cofounder of the FTD Disorders Registry.

#endFTD #GRN #FTDResearch

Now Live: FTD Disorders Registry Researcher Portal

Access secure, deidentified data from real-world lived experience of #FTD disorders. Design studies. Estimate recruitment. Accelerate progress.

Learn more: ftdregistry.org/for-research...

#FTDResearch #Neuroscience #EndFTD #AAIC2025

The FTD Disorders Registry and @theaftd.bsky.social are back at Booth 521 today at #AAIC2025! Stop by! We look forward to connecting and sharing how we're working together to advance #FTDresearch. #EndFTD #FTD

Come say hi to FTD Disorders Registry Director Carrie Milliard at Booth 521 today at #AAIC2025!

Learn how the FTD Disorders Registry is accelerating research and supporting scientists with real-world data.

#FTDRegistry #FTDResearch #EndFTD #Neuroscience

Shana Dodge & Penny Dacks are on the ground at #AAIC2025! Visit Booth 521 to learn how the FTD Disorders Registry supports your research with data, cohort tools & recruitment resources. Let’s move #FTDResearch forward together! #EndFTD #FTD #DementiaResearch

Coming to #AAIC2025? Visit Booth 521! The FTD Disorders Registry supports researchers with de-identified data and tools for study design, cohort discovery, and recruitment. Let’s move FTD research forward together. #EndFTD #FTDResearch #FTD

New Study Explores How FTD-Linked Genes May Shape Brain - FTD Disorders Registry Researchers have long understood that frontotemporal degeneration (FTD) is a neurodegenerative disease that begins in adulthood. But new questions are

Can FTD-linked genes shape brain development before symptoms appear?

A new study is exploring this question in families affected by genetic #FTD. Now enrolling across Canada and Europe.

ftdregistry.org/press/new-st...

#endFTD #FTDResearch

The Role of Longitudinal Data in Understanding FTD Progression - FTD Disorders Registry Learn how collecting longitudinal data helps researchers track FTD progression over time and develop more effective diagnostics and treatments.

Why does longitudinal data matter in #FTDresearch?

Tracking changes over time helps researchers understand how the disease progresses and how to treat it more effectively.

See how your data makes a difference:
ftdregistry.org/press/the-ro...

#FTD #endFTD

FTD Registry Launches New Researcher Portal to Accelerate Study Recruitment - FTD Disorders Registry The FTD Disorders Registry has launched a new Researcher Portal to accelerate study recruitment.

We have launched our new Researcher Portal. It is a powerful tool to help investigators access de-identified data and request Registry support to accelerate study recruitment.

Learn how it can help advance FTD disorders research: ftdregistry.org/press/ftd-re...

#EndFTD #FTDResearch

How Registry Data Is Advancing FTD Research—and Why It Matters - FTD Disorders Registry The FTD Disorders Registry is a powerful resource for scientists studying FTD disorders. Learn more about how your de-identified data is used.

Learn how information shared by Registry participants is helping researchers better understand frontotemporal degeneration — and why it matters.

Read more: ftdregistry.org/press/how-re...

#endFTD #FTD #ftdresearch

Role of glial cells in synaptic dysfunction

#Neuroscience

#Neurodegeneration

#ALSResearch

#FTDResearch

#BrainResearch

#GlialCells

#SynapticFunction

#Astrocytes

#Microglia

#CellBiology

#ScientificResearch

#Biotech

#LabScience

#MedicalResearch

#ResearchInnovation