This review describes the role of the transcription factor SOX4 in #LiverDisease & #HCC progression, highlighting it as a promising #TherapeuticTarget to modulate #Fibrogenesis and overcome #DrugResistance.

#OpenAccess: doi.org/10.1016/j.ge...

Welcome @cemm-vienna.bsky.social @bsky.app !!
The #HEPEX Lab @meduniwien.ac.at is part of #CeMM and investigates molecular mechanisms of #Fibrogenesis and #PortalHypertension

These speakers from Cedars-Sinai, Sanford Burnham Prebys, Vanderbilt University, and Penn State Cancer Institute will highlight diverse mechanisms underlying #fibrogenesis and discusses recent advances in identifying novel molecular targets for therapeutic prevention of #fibrosis bit.ly/3yOeuxu

BAUS-E
Wearable🤠bioadhesive Ultrasound shear wave #Elastography for continuous measurement of internal organ #Stiffness

Rat liver 48 h +nice correlation with timing of #Fibrogenesis
V 2.8 m/s->23 kPa
7.5 MHz, to 5 cm depth; 3 MHz to 7 cm depth

#ScienceAdvances 2024
www.science.org/doi/10.1126/...