This Week! Register now for the AGeD Pilot Award Informational Webinar, where learn more about this novel pilot program supporting gene and gene network discovery in aging: bit.ly/4aSaRqZ #GeneDiscovery #AgingResearch @jacksonlab.bsky.social @uw-nsc.bsky.social @oknathanshock.bsky.social

New study reveals 3D genome reorganization in Actinidia arguta, identifies AaCBP60B-like as key gene for anthocyanin regulation. #3DGenome #Anthocyanin #GeneDiscovery @oxfordacademic.bsky.social
Details: doi.org/10.1093/hr/u...

A new review explores HMM, their algorithms and applications in #Bioinformatics, from #GeneDiscovery to #SequenceAnalysis, highlighting their strengths, limitations, and potential to address complex biological problems. #HiddenMarkovModels #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Our study revealed 37 genes with robust causal links to #CRC risk using 3 different TWAS approaches. 10 of these genes are novel findings not previously reported by TWAS. This significantly expands our understanding of CRC's genetic susceptibility. 🧬 #GeneDiscovery 4/7

Easily explore any genome. Download annotated genes and design your experiment. 6 MONTHS FREE (UNTIL MAY 25th)

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#Photo51 #genebrowser #genediscovery #insilico

Association of the tomato co-chaperone gene Sldnaj harboring a promoter deletion with susceptibility to Tomato spotted wilt virus (TSWV) Abstract. Tomato spotted wilt virus (TSWV) poses a significant threat as a devastating pathogen to the global production and quality of tomato (Solanum lyc

Unlock new TSWV susceptibility gene in tomatoes via natural deletion, boosting resistance breeding! #TSWV #TomatoResistance #GeneDiscovery @OxfordJournals
Details: doi.org/10.1093/hr/u...

MorPhiC Consortium: towards functional characterization of all human genes | Nature Recent advances in functional genomics and human cellular models have substantially enhanced our understanding of the structure and regulation of the human genome. However, our grasp of the molecular functions of human genes remains incomplete and biased towards specific gene classes. The Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium aims to address this gap by creating a comprehensive catalogue of the molecular and cellular phenotypes associated with null alleles of all human genes using in vitro multicellular systems. In this Perspective, we present the strategic vision of the MorPhiC Consortium and discuss various strategies for generating null alleles, as well as the challenges involved. We describe the cellular models and scalable phenotypic readouts that will be used in the consortium’s initial phase, focusing on 1,000 protein-coding genes. The resulting molecular and cellular data will be compiled into a catalogue of null-allele phenotypes. The methodologies

Unlocking gene mysteries! 🎯 MorPhiC Consortium's goal: catalog phenotypes of null alleles for all human genes. Let's dive into 20,000+ genes! 🔬 #GeneDiscovery PMID:39939790, Nature 2025, @Nature https://doi.org/10.1038/s41586-024-08243-w #Medsky #Pharmsky #RNA 🧪