The WNT5B-NFATc2-MMP14 axis is a critical driver of #HuntingtonsDisease, accelerating ECM degradation, and therapeutic modulation of this pathway with #Genistein reduces #Neuropathology and improves motor coordination. @bumedicine.bsky.social
#OpenAccess: doi.org/10.1038/s413...
In silico computational screening and molecular dynamics analysis unveil Moringa oleifera phytochemicals as a promising PPAR-γ receptor agonist for targeted diabetes management strategies
Screening 42 #Phytochemicals from #MoringaOleifera identified #Epicatechin and #Genistein as potent PPAR γ modulators with superior binding affinity to #Rosiglitazone, underscoring their promise as natural #Antidiabetic agents for #T2DM therapy.
Open Chemistry: doi.org/10.1515/chem...
#Astrocytic WNT5B–NFATc2 signaling drives MMP14-mediated #ECM degradation and MSN damage in #HuntingtonsDisease, while #genistein suppresses this pathway to rescue #neuropathology, motor deficits, and lifespan. @bumedicine.bsky.social
#OpenAccess in #STTT: doi.org/10.1038/s413...
Daidzein and genistein for treatment of menopause
Of course, if you do not like tofu, you can buy a dietary supplement with a high content of these substances in a pharmacy or in a specialized store.
#menopause #daidzein #genistein #Daidzeinmenopause
#FactsFriday
Genistein, a prodominent isoflavone found in red clover, has multiple robust anti-tumor effect in various cancers, especially breast cancer and prostate cancer. Read the full study here: pubmed.ncbi.nlm.nih.gov/24331293/
#essiac #essiactea #genistein #antitumor #naturalremedies
