KAT2A-mediated #succinylation of the #splicingfactor SRSF11 at K419 enhances #DNARepair and #radioresistance in #HCC by promoting RAD52 exon inclusion, linking #AlternativeSplicing to #GenomicStability and offering a potential therapeutic target.
#STTT: doi.org/10.1038/s413...
Hashtag
#GenomicStability
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๐งฌ Don't miss the fourth and final session of NAR Cancer's 5th Anniversary Virtual Symposium!
๐ Thursday 17 April at 12pm US Eastern time
๐ฅ Speakers include Dr Elise Fouquerel and Dr Robert W. Sobol
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#NARCancer #PARPInhibitors #DNARepair #GenomicStability
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๐งฌ Don't miss the 4th session of NAR Cancer's 5th Anniversary Virtual Symposium!
๐ Thursday 17 April - 12pm US Eastern time
๐ฅ Featuring Dr Elise Fouquerel and Dr Robert W. Sobol
๐ Register here: lnkd.in/eRxxSxeu
#NARCancer #CancerResearch #DNADamage #DNARepair #GenomicStability #PARPInhibitors
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