🔦 Have you seen this new Research Protocol?

Homologous expression and purification of human HAX-1 for structural studies

🔓 buff.ly/WLKEUGV

#StructuralBiology #HAX1

We focus on #FAM136A, an orphan protein involved in familial #Menieres, an inner ear condition – not considered to be a mito disease!

We show that in #FAM136A ko:
⬇️IMS protein #CLPB #HAX1
⬇ #OXPHOS in cells, mice and patient LCLs

A #mito origin in #Menieres disease?!?

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