Viral entry shapes HCMV latency establishment - Nature Communications HCMV infection can become productive or latent. Here the authors show that variations in the number of incoming viral particles across cell types is a key factor of this decision, identifying entry efficiency as a key regulator of latency.

New study shows that inefficient virus entry into monocytes partly drives establishment of #HCMV #latency, with integrin β3 identified as a key entry factor modulating productive versus latent infection. #virology
📄 https://doi.org/10.1038/s41467-025-68063-y
👤 EVBC member: Noam Stern Ginossar

Understanding How a Common Virus Manipulates Host DNA - News Center Northwestern Medicine scientists have discovered how a common virus linked to birth defects and chronic illness manipulates host DNA, according to a new study published in Nature Communications.

Understanding how a common virus manipulates its host's DNA

(Human #cytomegalovirus #HCMV is known to be linked to birth defects and chronic illness)

#virology #herpesvirus #chromatin

Understanding How a Common Virus Manipulates Host DNA - News Center Northwestern Medicine scientists have discovered how a common virus linked to birth defects and chronic illness manipulates host DNA, according to a new study published in Nature Communications.

Understanding how a common virus manipulates its host's DNA

(Human #cytomegalovirus #HCMV is known to be linked to birth defects and chronic illness)

#virology #herpesvirus #chromatin

Human Cytomegalovirus HCMV infection is regulated by Glycoprotein B (gB) making it a target for neutralizing antibodies and a vaccine candidates. This 3D printed model of #HCMV Glycoprotein B visualizes where neutralizing antibodies bind the glycoprotein. buff.ly/9hXrp6F

How HCMV hijacks host cells — and beyond Ileana Cristea, an ASBMB Breakthroughs webinar speaker, presented her research on how viruses reprogram cell structure and metabolism to enhance infection and how these mechanisms might link viral…

How the human #cytomegalovirus hijacks host cells

| #virus | #HCMV | #infections | Via @asbmb.bsky.social

OK, but what do these new ORFs do? Like in #SARSCoV2, peptides from microproteins detected by MPRP were presented on MHC-I in cells infected with #HCMV and #VACV — suggesting a role in antiviral immunity

MPRP works across diverse viral families. We observed striking similarity in ribosome footprints on certain annotated and non-canonical ORFs between MPRP and virus-infected cells—including a newly revealed internal ORF in #flu and a well-studied ribosome stalling site in #HCMV

Gave my first conference talk at this week #Microbio25. I was positively surprised with the interest it garnered, and the friendly discussions during the Q&A and the days that followed. Looking forward to more meetings like this.

@microbiologysociety.org
#virology #hcmv #research

RESIST Seminar lecture by PD Dr. Bošnjak Exciting topics, interestingly presented: Every first and third Thursday (except during school holidays), RESIST scientists or top-class researchers from external institutions present their topics at ...

Listen to this exciting lecture on Thursday! Berislav Bosnjak will report in his lecture on 20 February at 1 pm on how #HCMV escapes #immune_protection.
www.resist-cluster.de/en/veranstal...

Decades of research push cytomegalovirus vaccine closer to reality Researchers review decades of progress in human cytomegalovirus (HCMV) vaccine development, emphasizing challenges, innovative platforms, and the critical need for effective prevention strategies.

Decades of research push cytomegalovirus vaccine closer to reality 🌍💉🧬 www.news-medical.net/news/2025010... #HCMV #VaccineResearch #Cytomegalovirus #GlobalHealth #Medical #InfectiousDiseases #PublicHealth #Vaccines #Health #Virology

Common Gut Infection Tied to Alzheimer’s Disease | MDedge Experts speculate HCMV may travel via the vagus nerve from the colon to the brain where it triggers the onset of AD.

www.mdedge.com/neurology/ar... #medicine #hcmv #alzheimers

🙏🏻 Merci à la Ligue Contre le Cancer pour son soutien - projet #HCMV & #Glioblastome 🦠 🧠

Human Cytomegalovirus infection is regulated by Glycoprotein B making it a target for neutralizing antibodies. This 3D printed molecular model of #HCMV Glycoprotein B visualizes where neutralizing antibodies bind the glycoprotein. Submit a protein model #3Dprint request. https://buff.ly/439KJRk

Discovering the tactics of #HCMV: The herpes virus, outwits our cells. How? New findings from @theliulab & @ChariteBerlin @FU_Berlin about interaction between HCMV and its host cells. Dive into research published in #NatureMicrobiology 👇
https://t.co/H0x5B8y7nY #LeibnizFMP

Scientists launch a pre-emptive strike on deadly post-transplant Around 80% of the UK population is currently infected with human cytomegalovirus (HCMV) and in developing countries this can be as high as 95%. The virus can remain dormant in our white blood cells

A team from the School of Clinical Medicine has discovered a potential new treatment to protect immunosuppressed patients from human cytomegalovirus #HCMV

➡️#infectiousdiseases #transplant

ow.ly/SRBW50DIRXq

"One Ring to rule them all, one Ring to find them" - One Ring to bring a Herpesvirus and in the autophagous vesicles wrap it
Read the Esclatine paper and find out how #HCMV rules #autophagy machinery for its own benefit@I2BCParisSaclay , @UnivParisSaclay

rdcu.be/buRzx

Poster of #HCMV sequencing using @nanopore by @rjrtn and @CVRbioinfo at #DVV2018 and #GfV2018