Innovative Research Enhances Understanding and Treatment of Sickle Cell Disease Recent findings from the American Society of Hematology highlight important developments in the treatment and management of sickle cell disease, providing new hope.

Innovative Research Enhances Understanding and Treatment of Sickle Cell Disease #United_States #Orlando #gene_therapy #sickle_cell_disease #Hydroxyurea

Hydroxyurea-induced severe interstitial pneumonitis: A case report Hydroxyurea-induced severe interstitial pneumonitis: A case report

Letter to editor

Hydroxyurea-induced severe interstitial pneumonitis: A case report

#Hydroxyurea #Interstitial #Pneumonitis #Dyspnea #Pulmonary #Toxicity

www.em-consulte.com/article/1780...

Timelapse depicting NPC clustering and ER expansion in a Schizosaccharomyces pombe cell expressing Cut11-GFP and mCherry-AHDL after exposure to 150 mM HU for two hours before the beginning of the experiment. Arrows show the appearance of cortical ER expansions.

The ER provides the proper redox environment for S-S bond formation & protein folding. This study shows that the #cancer drug #hydroxyurea disrupts redox-dependent folding in the #ER, triggering a stress response, ER expansion & cytoplasmic protein aggregation @plosbiology.org 🧪 plos.io/47U6ry0

Timelapse depicting NPC clustering and ER expansion in a Schizosaccharomyces pombe cell expressing Cut11-GFP and mCherry-AHDL after exposure to 150 mM HU for two hours before the beginning of the experiment. Arrows show the appearance of cortical ER expansions.

The ER provides the proper redox environment for S-S bond formation & protein folding. This study shows that the #cancer drug #hydroxyurea disrupts redox-dependent folding in the #ER, triggering a stress response, ER expansion & cytoplasmic protein aggregation @plosbiology.org 🧪 plos.io/47U6ry0

Timelapse depicting NPC clustering and ER expansion in a Schizosaccharomyces pombe cell expressing Cut11-GFP and mCherry-AHDL after exposure to 150 mM HU for two hours before the beginning of the experiment. Arrows show the appearance of cortical ER expansions.

The ER provides the proper redox environment for S-S bond formation & protein folding. This study shows that the #cancer drug #hydroxyurea disrupts redox-dependent folding in the #ER, triggering a stress response, ER expansion & cytoplasmic protein aggregation @plosbiology.org 🧪 plos.io/47U6ry0

Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series Determine efficacy and adverse events (AEs) of hydroxyurea (HU) in mast cell activation syndrome (MCAS) patients who were refractory to standard medical therapy. An electronic chart review was performed to find MCAS patients who received HU in a ...

[13:03] hydroxyurea used to treat a person w/ POTS & MCAS

Here's an article on the topic:

Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series [2022]
pmc.ncbi.nlm.nih.gov/articles/PMC...

#MCAS #hydroxyurea

Brayden Yellman, MD | Underappreciated Co-Morbidities in ME/CFS
video uploaded Oct. 16, 2025
youtu.be/od0epKW19og
#MECFS #MCAS #POTS #DrugRepurposing #hydroxyurea #MastCells #immunology

Disappointed w/new commercial form of #hydroxyurea - Xromi by #RareDiseaseTherapeutics. 👎👎

1. No communication to clinics/ppl living with #sicklecelldisease & what it means for them:
- 10x the💰
- frequent prior auths

2. Safety info discusses side effects in myeloproliferative disease, NOT SCD

Primary #Thrombocythemia, thrombosis treatment

1. Low risk population
Low-dose #aspirin, as a basic treatment, is used to reduce the risk of thrombosis

2. High risk population
#Hydroxyurea can inhibit excessive proliferation of platelets

Https://ja.ma/4hxjc3v

Wow, this is phenomenal work you've done and are doing @drpowerhays.bsky.social !🙌🏿😇
#sicklecell #hydroxyurea
#sicklecellinafrica
#sicklecellisglobal
#hemeonc

www.dorisduke.org/news--insigh...

Thank you @DorisDukeFdn for this beautifully written article and for supporting the care of children with #sicklecell globally

I'm honored to be a part of the team. Let's do this!
ddcf.org/news--insigh... #sicklecellmatters #conquerSCD #hydroxyurea #ADAPT🩸 #globalhealth