This review summarizes Rho/ROCK signaling mechanisms, their roles in diverse diseases, and recent advances in developing ROCK inhibitors as promising therapeutic agents.
#IJDDP #Rho #ROCK #inhibitor #therapy
www.sciltp.com/journals/ijd...
This review highlights the mechanisms of action of several key alkaloids in heart failure, arrhythmia, hypertension, myocardial infarction, and fibrosis.
#IJDDP #alkaloids #Cardiovascular #arrhythmia #hypertension
www.sciltp.com/journals/ijd...
This study demonstrates Guilu Bushen Pill promotes osteoblast differentiation and alleviates osteoporosis in OVX rats, linked to bone formation and metabolic modulation.🦴
#IJDDP #GLBSW #osteoporosis #metabolism #TraditionalMedicine
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This review highlights diabetic cardiomyopathy as a key contributor to heart failure in diabetes, outlining structural features, complex pathogenesis, and potential therapeutic implications.
#IJDDP #diabetes #cardiomyopathy #therapy
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This study extracts and purifies Qifuyin polysaccharides, identifying QFYP-1 and QFYP-2, and confirms their antioxidant properties and regenerative potential in planaria models.
#IJDDP #Qifuyin #antioxidant #regeneration #planaria #medicine
www.sciltp.com/journals/ijd...
This review summarizes the pathological mechanisms and therapeutic strategies for erectile dysfunction, encompassing lifestyle, pharmacological, physical, stem cell, and surgical approaches.
#IJDDP #ED #pathophysiology #therap
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This review examines gut fungi roles, study challenges, metagenomics and metabolomics advances, and potential therapeutic applications and future directions.
#IJDDP #GutMicrobiota #fungi #metagenomics #metabolomics
www.sciltp.com/journals/ijd...
The article explored novel therapeutic approaches targeting mitochondria-endoplasmic reticulum contact sites, which may be valuable for metabolic and vascular diseases.
www.sciltp.com/journals/ijd...
#IJDDP #MERCSs #neurodegeneration #Alzheimer #Parkinson
Inhibition of extracellular signal-regulated kinase 1/2 (ERK1/2) cascade might have dual effects in the treatment of cancer and heart disease, potentially bringing both benefits and adverse impacts.
www.sciltp.com/journals/ijd...
#IJDDP #Cancer #heartfailure #inhibitor
