Study Sheds Light on Pathogenesis of Myasthenia Gravis A team of researchers worked to shed light on the mechanism of CD4-positive T-cell regulation by IMPDH2 in MG.

The inosine-5′-monophosphate dehydrogenase-2 (#IMPDH2) enzyme is highly expressed in peripheral blood mononuclear cells and CD4-positive T cells from patients with #MyastheniaGravis (MG). Study in Clinical Immunology.

Read more: https://bit.ly/44BygsA

#RareDisease #MedSky

Domain-specific AI segmentation of IMPDH2 rod/ring structures in mouse embryonic stem cells - BMC Biology Background Inosine monophosphate dehydrogenase 2 (IMPDH2) is an enzyme that catalyses the rate-limiting step of guanine nucleotides. In mouse embryonic stem cells (ESCs), IMPDH2 forms large multi-prot...

Our new paper just arrived! Fun collaborative effort led by Sam Ball and Meagan Hennessy to develop an AI tool to segment and classify #IMPDH2 rod-rings in mouse ESCs doi.org/10.1186/s129...

Che-Chia Hsu, Hui-Kuan Lin et al. show that #IMPA1-derived inositol maintains stemness in castration resistant #ProstateCancer via #IMPDH2 activation. rupress.org/jem/article/...

📘 In our #Immunometabolism 2025 collection: rupress.org/jem/collecti...

Che-Chia Hsu et al. show that #IMPA1-derived inositol maintains stemness in castration resistant #ProstateCancer via #IMPDH2 activation. rupress.org/jem/article/...

📘 In JEM #Cancer Collection rupress.org/jem/collecti...

#AACR25

Che-Chia Hsu et al. show that #IMPA1-derived inositol maintains stemness in castration resistant #ProstateCancer via #IMPDH2 activation. rupress.org/jem/article/...

📘 In Tumor #Metabolism 2025: rupress.org/jem/collecti...
#KSTumorMetab25