As mentioned before, I have been working on the introduction of #RegisteredReports at QLR for the better part of two years now.
Now that this process is coming to an end (see announcement around #ISOQOL19), I thought I point to some resources.
#WeekendReads
[Thread of ~10]
#ISOQOL19 Poster available for download:
It presents #psychometric work on the #EQ5D in people living w #diabetes & severe #mentalillness-es.
Work was funded by @DiabetesUK & informs measurement in the ongoing DIAMONDS programme (@IMPACT_NIHR).
#HRQOL
Took a while, but back from #SanDiego trip. On top of world leading #HRQOL science, some great days, immediately favourite places.
#ISOQOL19 #coffee #acai
#portsidegelato @Better_Buzz
Arrived home from #ISOQOL19 or still travelling?
Why not read the three finalist papers of QLR's 2018 Article of the Year competition?
1)
2)
3)
#openaccess #psychometrics
@ISOQOL @SpringerPBH
Yuelin Li describes analysing how complex sets of objects are related: The Infinite Relational Model.
[direct pdf link on model]
#machinelearning #Bayes
#ISOQOL19
Presenting preparatory work for the DIAMONDS network at #ISOQOL19 (poster 3050):
Validity of diabetes-related psychosocial PROMss in people living with #diabetes & w/o comorbid severe mental illness.
#secondarydata #DAWN2 #mentalhealth #psychometrics
@IMPACT_NIHR
What are the challenges when implementing & managing FAITHFUL electronic implementations of clinical outcome assessments?
@CaroAnfray describes the development of practical guidelines.
#ISOQOL19 #oralsession207
Thoughts on how to optimise workflows for the collection of the #PHQ9 presented by @c_seegs.
How to integrate the patient voice better through #ePRO #implementation, was explored via #participatory action research:
#isoqol19 #oralsession207
#openaccess
Benjamin Schalet starts with #NAMVitalSigns👇👇:
Their goal was to measure "engaged people" better.
#ISOQOL19 #oralsession207
Large scale #implementation of PROMs in practice contexts, Rachel Sisodia:
4 million PROMs collected;
covering 51 medical specialties;
in 100 locations.
Collection success rate in first month highly predictive of services ever successful collecting.
#ISOQOL19 #oralsession207
Tenbroeck Smith: The Dynamic Sustainability Framework supports the development, testing of falsifiable hypotheses & continued learning to advance the #implementation, transportability & impact of health services research:
#oralsession207 #isoqol19
There is a role for #mixedmethods approaches to elicit supplementary data on patient experience & individual perceptions of benefit, risk & tradeoffs in drug development:
#ISOQOL19 #Symposium3
QLR issued two calls for papers in 2019 (👇👇):
- Feedback call: 27 manuscripts invited;
- Nonpar IRT: 14 abstracts received, invitations under way!
The next call for papers deals with OVERTREATMENT & OVERMEDICALISATION:
#ISOQOL19
@ISOQOL @SpringerPBH
Resources for engaging with the Normalization Process Theory are flagged up by
@CarlRMay
:
#implementationscience #ISOQOL19
Amy Kilbourne presents on how to put these strategies and #researchdesign-s into practice based on their "Adaptive Implementation of Effective Programs Trial (ADEPT)":
#ISOQOL19
Amy Kilbourne discusses different implementation strategies, for example based on this expert-defined classification:
#implementationscience #ISOQOL19
Emmons demonstrates that PRECIS could be a useful tool that can help trialists to ensure that their design decisions are consistent with the stated purpose of the trial.
#researchdesign #ISOQOL19
#implementationscience
Figures 1 and 2 of
were discussed in detail by Emmons at #ISOQOL19:
Challenges and solutions to #researchdesign problems in
#implementationscience
Emmons refers audience to tools for research planning available at @WUICTS:
In particular, D&I Toolkits:
e.g., the research design tool:
[pdf direct link]
#researchdesign #implementationscience
#ISOQOL19
Karen Emmons referring to the traditional "research pipeline", which is in need of considering much more the settings in which
- evidence is produced
- evidence is needed
#openaccess #ISOQOL19
#implementation
The development of the Portuguese #EQ5D-5L value set was discussed at #ISOQOL19. The paper can be read here:
#utilities #valuation #healtheconomics
Presenting preparatory work for the DIAMONDS network at #ISOQOL19 (poster 1044):
Evaluating the validity of the #EQ5D-3L & describing #HRQoL in people living with #diabetes & w/o comorbid severe mental illness.
#secondarydata #DAWN2 #mentalhealth #psychometrics
@IMPACT_NIHR
Todd DeWees presents #cuttingedge application of artificial neural network (ANN) analysis using #LIME to address the non-interpretability of ANN.
Some notes on LIME (not citrus-related), can be found here:
#ISOQOL19
More useful & usable ways to assess PROs. @DrCGibbons presents #cuttingedge ways to identify narrower conditional prediction distributions.
IMPORT demo page:
Related #machinelearning tutorial by the team:
#ISOQOL19
The next #cuttingedge research comes from @Angela_M_Stover.
Electronic Patient Reporting of Symptoms During Cancer Treatment #PRO-TECT:
- Registration:
#ISOQOL19
Lotte Haverman presenting #cuttingedge research & implementation of the @KLIKproject #feedback system:
#ISOQOL19 #patientcentered
Followup Plenary#1 #ISOQOL19:
Journals can have a role in disseminating trials independent of outcomes.
Supported by the @ISOQOL Board of Directors, #QLR has committed to introducing #RegisteredReports as soon as possible:
Separating the evaluation of research from its results.
In the presentation @pkluetz refers to the FDA Clinical Trial Endpoints for the Approval of
Cancer Drugs & Biologics (Guidance for Industry):
[direct pdf download]
#ISOQOL19
Robert Kaplan presents on the many problems of replication & disclosure in (drug) trials.
Good moment to shout out:
At #QLR we are working on introducing registered reports as soon as possible!
#ISOQOL19 #RegisteredReports #preregistration
@ISOQOL @SpringerPBH
Read the #ISOQOL19 conference abstracts in the QLR October supplement:
#qol #hrqol #healtheconomics
@SpringerPBH @JPRO_ISOQOL @ISOQOL
