Science Seminar on 16 April 2pm with Prof. Jonathan Yewdell (NIH): How MHC I Peptides Are Generated for #Viral and #Cancer #Immunosurveillance. Please register at shorturl.at/uptMY

Using an ABEmax 820k-#sgRNA library, this study maps #mutations that alter PD-L1 and HLA-I expression and identifies SETD2_Y1666 as a clinically relevant regulator of #cancer #Immunosurveillance. #medsky @pku1898.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

📢 #LAQV Webinars
Join us Dec 10, 12h WET!
👉 Lucília Saraiva on beating #hard-to-treat cancer with a first-in-class DDR #inhibitor
👉 Sara Granja on #CD147 & #immunosurveillance
👉 Andreia M. B. da Costa on #pharmacotoxicology of #psychedelics
Chair: Conceição Santos
💻 meet.google.com/kes-ocwa-mfv

Hepatocyte TM4SF5 mediates HCC progression by reducing natural killer (NK) cell cytotoxicity, while TM4SF5-specific isoxazole-based small molecules (TSIs) enhance NK cell-mediated #immunosurveillance to mitigate #HCC.

#STTT #OpenAccess: doi.org/10.1038/s413...

Graphic announcing Dr. Robert Binder's presentation at the Cell Stress Society international symposium

Catch Dr. Robert Binder's talk tomorrow at the Cell Stress Society International @stresscell.bsky.social symposium in Syracuse, NY. He'll be discussing his research on the importance of heat shock proteins for #cancer #immunosurveillance

This study identified a largely predominant #SenescentCell population and a minority proliferative cell in GCMN and showed that anti-Bcl2 therapy eliminates GCMN by inducing #Senolysis and #Immunosurveillance. #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

⏱️ Live Feed: Pr Laurence Zitvogel (Gustave Roussy, France) talked about the #metabolism at the cross road between gut #commensalism and
cancer #immunosurveillance.

⏱️ Live Feed: #Neuroendocrine Control of Cancer #Immunosurveillance, featuring Guido Kroemer.
Spotlight on #ACBP / #DBI, a newly identified #gerogene / #geroprotein with age-dependent expression

Hepatocyte TM4SF5 reduces natural killer (NK) cell cytotoxicity to promote #LiverCarcinogenesis and TM4SF5-specific isoxazole-based small molecules mitigate #HCC by increasing NK cell-mediated #immunosurveillance. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...