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#IntestinalStemCells
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Cellular and Molecular Gastroenterology and Hepatology (CMGH)
Cellular and Molecular Gastroenterology and Hepatology (CMGH)
@aga-cmgh.bsky.social
1 month ago
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🔎 New research reveals inflammatory secretory progenitor cells in #crohnsdisease with open chromatin at inflammatory gene loci—showing how gut epigenetics are rewired in #IBD #IntestinalStemCells #EditorsEssentialReading
🔗 https://ow.ly/Rgqa50YhigW

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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
1 month ago
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Intestinal #TregCells promote epithelial repair by combining #IFNγ and #IL10 signaling to drive #organoid growth, preserve #IntestinalStemCells, and enable #gut regeneration.
@tum.de @univparissaclay.bsky.social

#OpenAccess in #STTT: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
4 months ago
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MG53 promotes secretory lineage commitment via asymmetric division of #IntestinalStemCells (ISCs) in a #PPARα-dependent manner, minimizing #Inflammation, thus highlighting the MG53-PPARα axis in intestinal protection. @pku1898.bsky.social

#OpenAccess: doi.org/10.1038/s413...

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