Current #status of #intranasal and inhaled #COVID19 #vaccines

Current #status of #intranasal and inhaled #COVID19 #vaccines, etidiohnew.blogspot.com/2026/04/curr...

This study shows heterologous #intranasal boosting with RBD-HR after mRNA priming enhances mucosal, humoral & #CellularImmunity against #SARSCoV2, inducing strong #NeutralizingAntibodies, SIgA, TRM cells & CD103⁺ DC activation.

#OpenAccess: doi.org/10.1016/j.ge...

Intranasal vaccine booster shows stronger immune response and protection against sarbecoviruses Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and Monash University in Australia have demonstrated that an intranasal vaccine booster may confer…

#Intranasal #vaccine booster shows stronger immune response and protection against #sarbecoviruses ...

| #immuneresponse | #virus | #mRNA | #vaccine | Via @sciencex.bsky.social

Working together: a multi-component intranasal vaccine provides synergistic protection against COVID-19 - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Working together: a multi-component intranasal vaccine provides synergistic protection against COVID-19

Multi-component #intranasal #vaccine provides synergistic protection against #COVID-19 ...

| #nose | #coronavirus | #SARSCoV2 | #COVID19 | #infections | Via @nature.com

Therapeutic nasal HPV vaccine for cervical cancer treatment – BioNews Central New intranasal HPV vaccine shows promise as a non-invasive therapeutic option for women battling cervical cancer. ...

New #intranasal #HPVvaccine shows promise as a non-invasive #therapeutic option for #women battling #CervicalCancer.
#IntranasalVaccine 

7/8 "This trial shows that this #intranasal, shelf-stable #H5N1 #vaccine could play a major role in #pandemic #preparedness," said corresponding author Dr. Justin #Ortiz.

He noted it offers a "practical and scalable way to help protect people from evolving strains of the virus."

#Science #BirdFlu

5/8 This is the key breakthrough: The #intranasal $vaccine triggered both #mucosal & #systemic #immunity.

This is a major advance, as the authors note that "other intranasal recombinant H5 flu vaccines have not achieved [this] in clinical trials."

It was also found to be safe and well-tolerated.

4/8 Forty adults were given NanoVax's adjuvanted, #recombinant #intranasal #vaccine.

Participants who received the adjuvanted (boosted) vaccine had "higher levels of protective antibodies (immunoglobulin [Ig] G and A), more memory immune cells, and a better ability to neutralize infected cells."

1/8
🦠 INTRANASAL H5 BIRD FLU VACCINE PROVOKES BROAD IMMUNE RESPONSE 🦠

Mary Van Beusekom (CIDRAP) reports a Phase 1 trial of an experimental #intranasal H5N1 #vaccine generated a "broad #immune response" in adults, a major step in #pandemic preparedness.

#BirdFlu #H5N1 #AvianFlu #CIDRAP

An #intranasal adjuvanted, recombinant #influenza A/ #H5 #vaccine primes against diverse #H5N1 clades: a phase I trial

An #intranasal adjuvanted, recombinant #influenza A/ #H5 #vaccine primes against diverse #H5N1 clades: a phase I trial, etidiohnew.blogspot.com/2025/11/an-i...

Early-stage clinical trial demonstrates promise of intranasal influenza vaccine in generating broad immunity – BioNews Central Early trial results show an experimental intranasal influenza vaccine triggered a broad immune response against multiple H5N1 “bird flu” strains, highlighting the potential of mucosal immunization to protect against diverse influenza strains. ...

Early trial results show an experimental #intranasal #InfluenzaVaccine triggered a broad #ImmuneResponse against multiple #H5N1 #BirdFlu strains, highlighting the potential of #MucosalImmunization to protect against diverse #influenza strains.

Development of an #intranasal RNA–lipid #nanoparticle #CancerVaccine that triggers lung-localized T-cell immunity, enhances #CAR-T efficacy, and achieves potent #antitumor effects in #LungCancer models. @tsinghuauniversity.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

This study assessed diazepam pharmacokinetics (PK) in 2- to 5-year-olds with epilepsy; the PK profile matched the profile in patients ≥6 years.
doi.org/10.1111/epi....

#epilepsy #Epilepsia #ILAE #diazepam #intranasal #pediatric #rescuemedication #seizureclusters

A single-dose #intranasal #immunization with a novel #bat #influenza A virus-vectored #MERS #vaccine provides effective protection against lethal MERS-CoV challenge

A single-dose #intranasal #immunization with a novel #bat #influenza A virus-vectored #MERS #vaccine provides effective protection against lethal MERS-CoV challenge, etidiohnew.blogspot.com/2025/07/a-si...

Meaning of #intranasal INTRANASAL inside the nose. .. intranasal

Needle-Free: New Nano-Vaccine Effective Against All COVID-19 Variants A new nano-vaccine developed by TAU and the University of Lisbon offers a needle-free, room-temperature-storable solution against COVID-19, targeting all key variants effectively. Professor Ronit Satc...

Looking for the part that says in humans instead of in mice. But seeing "mucosal Immunity" was particularly gratifying. scitechdaily.com/needle-free-...
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/pdf/10.1...
#mice #human #vaccine #COVID-19 #intranasal #mucosalImmunity

Significado de #intranasal INTRANASAL al interior de la nariz... intranasal

Significado de #intranasal INTRANASAL dentro do nariz. .. intranasal

Intranasal vaccine shows broad SARS-CoV-2 variant protection Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutral...

Intranasal vaccine shows broad SARS-CoV-2 variant protection 🌍💉🔬 news-medical.net/news/2024090... #COVID19 #Vaccine #Immunization #SARSCoV2 #Intranasal #EmergingVariants #NeutralizingAntibodies #TcellResponse #BroadProtection #VaccineEfficacy