Find out how to answer scientific questions about #ligands in the #PDB directly from your web browser. Watch the latest talk by Ibrahim Roshan at the CCP4 Study Weekend 2026.

🎥 Watch the talk:
ukri.zoom.us/rec/play/U_J...

#PDBeKB #CCP4 #StructuralBiology

Your Top Technical Questions Answered - How to Solubilise CNO Need help solubilising your CNO? Our technical team answers your latest technical question and demonstrates how to solubilise Clozapine-N-oxide (CNO) dihydrochloride correctly.

🗣️ Your Top Technical Questions Answered!

In this new blog, our technical team share a step-by-step guide to effective solubilisation of CNO 👩‍🔬👨‍🔬

Find out more about one of our most popular DREADD ligands: ow.ly/7ttQ50XhIFA

#CNO #clozapinenoxide #chemogenetics #DREADD #ligands #lifescience #labhacks

Here's another important QSPainRelief publication about allosteric sites at #GPCRs: They can be identified by looking at how strongly certain receptor sites are coupled to #conformational changes that occur during activation.

🔗 doi.org/10.3390/ijms...

#allostery #pharmacology #receptors #ligands

We cover recent advances in atomistic simulations of #RNA: from #folding and #ion binding to interactions with #proteins and #ligands. A broad overview, with many references and open questions.

LIGYSIS-web relies on 3Dmol.js by @dkoes.compstruct.org to explore the #interactions between #proteins and relevant #ligands and deliver rich output including evolutionary #divergence across homologues, enrichment in human genetic #variation, solvent #accessibility and a #functional score!

✨ Most-Cited Article Collection ✨
Unlock the power of metal #catalysts in asymmetric C–H activation! This graphical review explores cutting-edge strategies, chiral #ligands & catalytic cycles shaping modern #synthesis.

🔗 Read now: www.thieme-connect.com/products/ejo...

Brighten your live-cell imaging with Janelia Fluor® HaloTag® Ligands, highly photostable, cell-permeable dyes for dynamic, high-resolution studies.

Explore more at: https://bit.ly/4jNKqn1

#CellImaging #LifeScience #Ligands

🍃 This paper studies the #molecular #pharmacology of Bryophyllum pinnatum #herbal preparations using specific receptor #ligands, the human myometrial #cell line hTERT‑C3, and cell lines expressing #recombinant human #oxytocin and V1A receptors.

💻 www.thieme-connect.com/products/ejo...

Enzyme-inspired ligand distinguishes between simple alkyl groups Designer ligand creates active site-like pocket for asymmetric radical reaction

Enzyme-inspired ligand distinguishes between simple alkyl groups #Science #Chemistry #OrganicChemistry #Enzymes #Ligands

jwohlwend/boltz: Official repository for the Boltz-1 biomolecular interaction model #boltz #biomolecular #interaction #prediction #modeling #protein #dna #rna #ligands

LIFE SCIENTISTS!! If you're looking for D-AP5, look no further! 👀

We have D-AP5 in stock & ready for immediate dispatch with fast delivery! Don't wait weeks for what you need - try Hello Bio today! 🚚📦

Find out more: ow.ly/mv4N50V6UCH

#DAP5 #neuroactive #ligands #receptors #antagonists

Organic ligands in whale excrement support iron availability and reduce copper toxicity to the surface ocean - Communications Earth & Environment Whales transform prey biomass into labile micronutrients and inject them directly into the surface ocean, according to chemical analyses of whale excrement samples from the Southern Ocean.

Superb new paper fills in key knowledge gaps in the role of whales (& impacts of #krill #fishery) in biogeochemical cycling of iron & copper in oceans www.nature.com/articles/s43... #ligands #SouthernOcean

Several papers recently cited our #BitterDB paper from 2019 - I want also to bring to attention to the 2024 update in #NAR #Bitter #taste #ligands #receptors doi.org/10.1093/nar/...
bitterdb.agri.huji.ac.il/dbbitter.php

The glycosyltransferase ST3GAL4 drives immune evasion in acute myeloid leukemia by synthesizing ligands for the glyco-immune checkpoint receptor Siglec-9 - Leukemia Leukemia - The glycosyltransferase ST3GAL4 drives immune evasion in acute myeloid leukemia by synthesizing ligands for the glyco-immune checkpoint receptor Siglec-9

A new paper by people I admire on ST3GAL4 driving #immune evasion in acute myeloid #leukemia by synthesizing #ligands for Siglec-9. 🧪 #science @natureportfolio.bsky.social
www.nature.com/articles/s41...

Understanding Ligand Exchange and Surface Passivation in CdS Quantum Dots from First Principles The capping ligands on quantum dots (QDs) play a critical role in determining their stability and properties, making the ligand exchange process pivotal. However, rational design rules for selecting l...

The Liu Lab provides research on structure–property relationships to pave the way for the rational design of effective #quantumdot ligands in Chemistry of Materials. #wsuchemistry #ligands #chemistryindetroit #QDs #ChemSky #ResearchSky

doi.org/10.1021/acs....

FS may suggest multiple binding sites. The problems we address are (1) #defining the distinct #sites (2) #identifying which sites are most likely to be #functional. Sites are first identified by #clustering #ligands based on their #interactions with the protein. Contacts calculated with #arpeggio

🚨 Heads up! Our PDBeChem (www.ebi.ac.uk/pdbe-srv/pdbechem/) service will be retired later this month. 🚨

But don’t worry - explore our new PDBe-KB ligand pages!

Explore new features using this example Imatinib page:
➡️ wwwdev.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/STI

#PDBe-KB #ligands

Makoto Fujita from the University of Tokyo just told us about the self-assembly of gigantic coordination #polyhedra, showing that well-designed #molecules are spontaneously organized into functional molecular systems. #ligands #oligopeptides @UTokyo_News_en

This may be a silly question but: is there a future where #catalyst #ligands are derived from #lignin's oxoaromatics?! As biomass fractionation gets better at creating reliable feedstock streams can we leverage #lignands? #realtimechem