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Rewiring an E3 ligase enhances cold resilience and phosphate use in maize - Nature The E3 ubiquitin ligase NLA postively regulates cold tolerance and negatively regulates phosphate uptake in maize, and a genetically engineered variant of this enzyme leads to improved cold ...

Rewiring an E3 #ligase enhances #cold resilience and #phosphate use in #maize

www.nature.com/articles/s41...

#PlantScience #SciComm @nature.com @natcellbio.nature.com @maizesausage.bsky.social @plantnerd.bsky.social @jchrispires.bsky.social @mrillig.bsky.social @nmouquet.bsky.social

Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development - Genes & Immunity Genes & Immunity - Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development

#Transcriptional #regulation of #Ligase IV by an #intronic #regulatory #element directs #thymocyte #development

#Genes & #Immunity @springernature.com
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DNA Replication Enzymes (Prokaryotic):
𝐇𝐞𝐥𝐢𝐜𝐚𝐬𝐞 → unwinds dsDNA @ oriC; 𝐓𝐨𝐩𝐨𝐢𝐬𝐨𝐦𝐞𝐫𝐚𝐬𝐞 𝐈𝐈 (DNA gyrase) → relieves +supercoils; 𝐒𝐒𝐁𝐏 → stabilizes ssDNA; 𝐏𝐫𝐢𝐦𝐚𝐬𝐞 (RNA pol) → lays RNA primers;

#MiniMedSchool #USMLE #InternalMedicine #MedicalEducation #Helicase #DNAgyrase #SSBP #Primase #DNAPol #Ligase

Structure of fungal tRNA ligase Trl1 with RNA reveals conserved substrate-binding principles - Nature Structural & Molecular Biology Köhler et al. present the crystal structure of fungal tRNA ligase Trl1-LIG bound to an activated RNA substrate, providing key insights into conserved substrate binding and activation, enzyme specifici...

Trl-ing Research!
#tRNA #Ligase #Trl1 #Yeast #RNA

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