Long noncoding RNA TUG1 promotes chondrosarcoma progression while driving M2 macrophage polarization.
#TUG1 #lncRNA #Chondrosarcoma #M2Polarization #TumorMicroenvironment #BoneCancer
www.sciencedirect.com/science/arti...

#CDK5RAP3 regulates hepatic #glucosemetabolism, and its hepatocyte-specific loss drives liver disease marked by steatohepatitis, macrophage #M2polarization, and disrupted UDP-glucose metabolism via HSP90AA1–UGP2/PGM1. @emorydeptofmed.bsky.social

#OpenAccess: doi.org/10.1016/j.ge...

This study shows that inhibition of S1pr3 ameliorates #Bleomycin-induced pulmonary fibrosis by suppressing #Macrophage #M2Polarization via the #PI3K/Akt-Stat3 pathway, suggesting S1pr3 as a #therapeutic target for #PulmonaryFibrosis. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

This study identifies #SaltInducibleKinases, especially SIK3, as inhibitors of #macrophage efferocytosis in #RheumatoidArthritis, showing that SIK inhibition enhances #apoptotic cell clearance, #M2polarization, and Treg differentiation.

#OpenAccess #STTT: doi.org/10.1038/s413...