🧬 The past year has seen huge progress across MAGIC — from refining 3D muscle constructs to expanding engineered tissue and multi‑organoid platforms.
These advances are giving us more predictive ex vivo models and helping accelerate the path toward next‑gen gene therapies.
#MAGICProject
Map of the world with pins where MAGIC is located - America, UK, Ireland, Spain, Portugal, Germany, Italy, Netherlands and more
Where is MAGIC? Across Europe and beyond.
Our consortium spans 10 countries, connecting leading institutions to tackle neuromuscular research challenges together.
🔗 magic-horizon.eu
#MAGICProject #ResearchCollaboration #NeuromuscularResearch
ICYMI: What’s next for neuromuscular treatment development?
MAGIC Project joined Muscular Dystrophy UK's Muscles Matter podcast to discuss SMA gene therapies, AI, and the future of collaborative research.
🎧 Listen: bit.ly/4aJpPodcast
#MAGICProject #GeneTherapy #Podcast
2026 written with a DNA strand coming out the 0
🎆 Happy New Year from the MAGIC Project! 🎆
In 2026, we’ll keep pushing boundaries in neuromuscular research:
✅ Better disease models
✅ Gene therapy innovation
✅ Stronger networks for translation
Learn more: magic-horizon.eu
#MAGICProject #HappyNewYear
A laptop with notebooks next to the MAGIC, EU horizon, UKRI and SERI logos
🔬 Curious about the latest progress in gene therapy for muscular dystrophies?
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
Images of 3 different presenters standing in front of their posters at ESGCT 2025
🔬 Earlier this month at #ESGCT2025, MAGIC partners
@crick.ac.uk
shared 3 posters on human models for neuromuscular gene therapy:
🧪 3D cultures for DMD
🧠 AAV dynamics in multi-organoids
🧬 Myotubular myopathy modelling
Pushing boundaries in patient-relevant research.
#genetherapy #MagicProject
Marco Wachowius from DINAMIQS stands in front of the poster titled "Single-Particle Analysis of AAV Vectors by Mass Photometry: Insights into Packaging Efficiency and Stability"
🔬 MAGIC at #ESGCT2025!
DINAMIQS shared how mass photometry boosts AAV packaging efficiency & stability.
📌 >95% full capsids = better stress resilience.
🚀 Fast, label-free AAV quality checks = smarter upstream optimisation.
#MAGICProject #GeneTherapy #AAV
Laptop and notebooks next to MAGIC project logo
🔬 Curious about the latest progress in gene therapy for muscular dystrophies?
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
#GeneTherapy #RareDisease
Hands wearing gloves, holding a pipette in a fumehood
🚨 New publication from the #MAGICproject!
A novel iPSC line from a UCMD patient with a COL6A1 mutation offers a valuable new model for studying collagen VI-related muscular dystrophies and testing therapies.
📖 Read the paper: www.sciencedirect.com/science/arti...
Graphic which says "stay informed on the latest advancements in muscular dystrophy treatments"
📫 Our next newsletter is landing in inboxes soon!
Subscribe to hear about the latest developments from the #MAGICproject:
🔬 Genetic therapies advances for muscular dystrophies
📰 Conference & event highlights
📝 New research publications
…& more!
👉 magic-horizon.eu/news-events/...
Image of a computer and notebooks alongside the MAGIC logo
🔬 Curious about the latest progress in gene therapy for muscular dystrophies?
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
#GeneTherapy #RareDisease
🚨 New pre-print from the #MAGICproject!
Our team modelled L-CMD, a severe laminopathy, using iPSC-derived skeletal muscle & showed how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.
biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC
🚨 New pre-print from the #MAGICproject!
We model L-CMD-a severe laminopathy-using iPSC-derived skeletal muscle & show how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.
www.biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC
Image of Professor Karen English alongside text Meet the MAGIC project members, Professor Karen English, Maynooth University
🔬 In the #MAGICproject, Prof. Karen English (@muresearch.bsky.social) is tackling immune reactions to AAV gene therapies for muscular dystrophy.
The goal: identify & calm early immune responses to boost safety & efficacy.
🔬 Full interview: magic-horizon.eu/news/meet-nu...
#GeneTherapy #AAV
Image of a person wearing gloves and a lab coat, using a pipette in a laboratory
🚨 New publication from the #MAGICproject!
A novel iPSC line from a UCMD patient with a COL6A1 mutation offers a valuable new model for studying collagen VI-related muscular dystrophies and testing therapies.
📖 Read the paper: www.sciencedirect.com/science/arti...
Stay informed on the latest advancements in muscular dystrophy treatments
📫 Our next newsletter is landing in inboxes soon!
Subscribe to hear the latest updates from the #MAGICproject, such as:
🔬 Advances in genetic therapies for muscular dystrophies
📰 Conference and event highlights
📝 New research publications
…and more!
👉 Sign up: magic-horizon.eu/news-events/...
Image of Eduard Ayuso wearing a lab coat in the lab. Quote "Together, we can turn cutting-edge research into real-world treatments that have a lasting impact."
From discovery to delivery, gene therapies must be scalable.
Siegfried DINAMIQS supports the #MAGICproject to tackle manufacturing early.
Eduard Ayuso: “...make groundbreaking therapies manufacturable at quality and cost for patients.”
🔗 magic-horizon.eu/news/meet-di...
Two researchers in a laboratory looking at a computer
Rare muscular dystrophies know no borders🌍
The #MAGICproject unites global researchers to develop genetic therapies.
Its now easier to learn about MAGIC's goals as our project leaflets are available in 6 languages!
Download 👉 magic-horizon.eu/media/leafle...
#MuscularDystrophy
Image of two people involved in the MAGIC project with text "meet the experts behind the MAGIC project"
🔬 Meet the minds behind MAGIC! Dive into our partner interviews to see how global experts are uniting to revolutionize gene therapies for muscular dystrophies.
Discover their stories and insights here: magic-horizon.eu/news-events/...
#MAGICproject #GeneTherapy #MuscularDystrophy
Accelerate genetic therapy development to impact the lives of people with muscular dystrophy
💫 The #MAGICProject is developing transformative gene therapies for people living with rare muscular dystrophies - conditions that affect movement, eating, breathing & more.
🧬 With leading experts on board, we’re pushing research forward, faster.
🔗 magic-horizon.eu
