Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation - Nature Communications The authors show that regenerating liver requires de novo pyrimidine synthesis and it uses ammonia as precursors differentially as it traverses the liver zones. Tracing studies and spatial metabolomic...

📄Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation. Nat Commun 16, 9664 (2025). doi.org/10.1038/s414...
International team driven by Jiri Neuzil @ibtcas.bsky.social
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#MassSpectrometryImaging
Laboratory of Molecular Structure Characterization, IMIC

Have you ever considered modeling a #MassSpectrometryImaging experiment with students? Here is a way to do it
-Print the outline of a tissue slice on paper
-Treat the papers with phenolphthalein in certain areas
-Reveal the shapes with Na2CO3 solution
Yay, you’ve made your first image!
#SciCommUU25

Spread the word! #IMSIS2025 #MassSpectrometryImaging #IMSIS3 #UCDavis #SpatialOmics #TeamMassSpec #MSI #IMS

Effortless Landmark Detection

Unsupervised spatial landmark detection-registration
Align HE Histology with #SpatialOmics
#Visium #SpatialTranscriptomics
#MassSpectrometryImaging

Also working on reconstructing 3D histology from serial slices
#NatureMethods 2024
www.nature.com/articles/s41...