A scene from Project Hail Mary in which Ryan Goslings character is strapped in his space shit and wearing glasses and devastatingly attractive because he is a genius microbiologist, cat nip for us nerds

Go see Project Hail Mary! #MicrobeSky #ScienceSky 🧪 🛰️

GBE | Recent Microbial Evolutionary Insights From Metagenomics

Moguel et al. publish a new Review on how metagenomics has revolutionized our understanding of microbial evolution, revealing lineages and functional adaptations, and reshaping our view of the Tree of Life.

🔗 doi.org/10.1093/gbe/evag029

🖌️ Laura Carrillo Olivas

#genome #evolution #microbesky

Origin and Evolution of Very Large Extracellular Proteins in Fructophilic Lactic Acid Bacteria Abstract. Large surface proteins in bacteria serve important functions in aggregation, biofilm formation, and cell interaction processes. In Apilactobacill

Pedersen et al. investigated the evolution and structure of Giant1-5 extracellular surface proteins in a defensive symbiont of the honeybee.

🔗 doi.org/10.1093/gbe/evag011

#genome #evolution #microbesky

Your breath tells a story about the neighborhoods in your gut. #MicrobeSky #ScienceSky 🩺 🧪 🦠

GBE | Origin and Evolution of Key Enzymes in the Anammox Pathway Revisited

@emilhaegglund.bsky.social @lionelguy.bsky.social et al. employed sequence-based and structure-based search methods to investigate the origin of the anammoxosome, the sole known energy-producing organelle in bacteria, and its key enzyme.

🔗 doi.org/10.1093/gbe/evaf244

#genome #evolution #microbesky

Uncovering hidden phylo: and ecogenomic diversity of the widespread methanotrophic genus Methylobacter Abstract. The globally distributed genus Methylobacter plays a crucial role in mitigating methane emissions from diverse ecosystems, including freshwater a

🚨 New paper out: Ecogenomics of Methylobacter 🦠

- three different MMOs to oxidize CH4 in single species
- machinery for nitrogen, sulfur, iron, and hydrogen metabolisms
- adaptations to low O2 conditions
...

led by @wutkowska.bsky.social

tinyurl.com/pmntwuk6
#MicrobeSky #pangenome

Comparative Genomics Reveals Multipartite Genomes Undergoing Loss in the Fungal Endosymbiotic Genus Mycetohabitans Abstract. Endosymbiotic bacteria extensively impact phenotypes of their eukaryotic hosts, while experiencing dramatic changes to their own genome as they b

@bhuwanabbot.bsky.social @morgancarterphd.bsky.social @raw937.bsky.social @andrabuchan.bsky.social et al. present a pangenome analysis of the endofungal genus Mycetohabitans, showing bacteria-fungus coevolution.

🔗 doi.org/10.1093/gbe/evaf231

#genome #evolution #pangenome #MicrobeSky

Beware, Solarion pops in between cat videos now. #ProtistsOnSky #MicrobeSky

ICYMI: Our latest shows what happens to transcriptional and metabolic profiles in a desiccated soil bacterium.

To simplify things, I've attached a visual abstract.

Comments on the preprint are welcome!
#microsky #microbesky

www.biorxiv.org/content/10.1...

Postdoc in ecogenomics and physiology of nitrifiers/methane-cyclers – ISME

🚨 Come and work with us 🦠🧪🖥️
Postdoc position with lots of freedom available in my group

- 1.5 years with options to extend
- work on ecogenomics and physiology of N/CH4-cyclers
- remote work possible 🤓

more info here: isme-microbes.org/postdoc-ecog...

#microbesky

#inktober day 16 with Blunder

Here I was rather inspired by a happy accident.

In 1928, Alexander Fleming discovered penicillin from a moldy Petri dish in his lab.

But did you know that the mold most likely came from a mycologist, C. J. La Touche, who worked one floor below?

#microbesky #sciart

#inktober day 15 with Ragged

It made me thought about the ragged edges observed on swarming motility plates.

Swarming bacteria form beautiful patterns, worth of an art exhibition 🖼️

#microbesky #sciart #inktober2025

#inktober day 13 with Drink

Microorganisms are essentials for fermentation in various products including beer, wine, kefir or kombucha.

With some friends we've already brewed our own beer, but lately I've become a huge fan of water kefir (especially with ginger).

#inktober2025 #microbesky #sciart

#Inktober days 11 + 12 with Sting & Shredded

Phages invade bacteria. Some bacteria fight back, cutting the phage DNA into small fragments with restriction enzymes.

These "scissors", which are part of RMS, can degrade foreign DNA, while leaving the bacteria's own DNA unharmed.

#microbesky #sciart

#Inktober days 8 and 9 combined - Reckless & Heavy

The reckless use of antibiotics in humans, animals and plants is the main driver in the development of antimicrobial resistance pathogens.

As one of the top global threats, AMR places a heavy burden on public health.

#inktober2025 #microbesky

#inktober day 7 - Starfish

Did you know that there are bacteria, called Stella vacuolata, with a star-shape ?

When autumn begins, they're usually two different mindests:
- Those who are already looking forward to the winter holidays 🎄
- And the fall lovers 🎃

#inktober2025 #sciart #microbesky

Beautiful work 🎉 that resolved a long standing question: tumor microbiome, do they exist?🦠🧪 #microbesky

Gut microbiologists’ “favorite?” bug 🦠, Bifidobacterium, co-evolves across animal host, with diet as a major selection force 🍎 #microbesky 🧪

AI mirrors experimental science to uncover a mechanism of gene transfer crucial to bacterial evolution By solving a previously unsolved biological question, the AI co-scientist predicted a complex mechanism of gene transfer and generated hypotheses that opened new research directions, illustrating AI's...

✨🧪 #microbesky #AI4S

AI mirrors experimental science to uncover a mechanism of gene transfer crucial to bacterial evolution By solving a previously unsolved biological question, the AI co-scientist predicted a complex mechanism of gene transfer and generated hypotheses that opened new research directions, illustrating AI's...

AI co-scientist successfully predicted bacterial HGT mechanism of cf-PICIs🦠🔬. Careful - the top hit works, the other 15 less promising. Funny how people feel impressed but not surprised. Eventually, we want good ideas to be more surprising than reassuring! www.cell.com/cell/fulltex... 🧪 #microbesky

A plasmid golden ratio? 🧬
Plasmid copy number ≈ 2.5% of chromosome size—consistent across bacterial species!
pmc.ncbi.nlm.nih.gov/articles/PMC... @jerorb.bsky.social
🧪 #microbesky

From bugs to drugs to bugs to (taste) buds (🦠 to 😋) - a new microbial research field putting microbes on the table 🍽️
Who’s up for starting a restaurant together? 👩‍🍳👨‍🍳
#Microbesky

From bugs to drugs to bugs to (taste) buds (🦠 to 😋) - a new microbial research field putting microbes on the table 🍽️
Who’s up for starting a restaurant together? 👩‍🍳👨‍🍳
#Microbesky #Microbiomesky

If you're interested in learning microbiology🦠, AI 🤖, and bioinformatics 🧬, check out our lab’s knowledge graph (built by Jeff—our in-house software engineer). An efficient way to train PhD students!
genomiverse.net/JeffsKnowled...
#Microbesky #Microbiomesky #AI4S #Bioinformatics

🦠💊Resistance genes were around before antibiotic - human use drove their spread and mobility. #Microbesky

Genomic and physiological characterization of 'Candidatus Methylocystis sumavensis', a novel acid-tolerant methanotroph from peatland Methanotrophic bacteria in peatlands mitigate emissions of methane (CH4), a potent greenhouse gas. Yet, the identity, physiology, and adaptive traits of methanotrophs inhabiting acidic peatlands are s...

📢 🦠 A new methanotroph from Czech peat! Through an effort led by PhD student in my group Justus Nweze we isolated and describe a new CH4-muncher. Potential for a flexible (annaerobic) metabolisms and cool pH adaptations.

www.biorxiv.org/content/10.1...
#microbesky #microbiomesky

A DNA capture approach for enrichment of nitrogen and methane cy...

🤩New recommendation out: DNA capture for sequencing genes in N&C cycling microbiol.peercommunityin.org/articles/rec... by Siljanen et al.

Thanks to W. Orsi, @kennethwasmund.bsky.social, and C. Wurzbacher for their review and Lizzy Wilbanks & Craig Herbold for handling.
#microbesky #microbiomesky

Hidden Markov Model-Based Prokaryotic Genome Space Mining Reveals the Widespread Pervasiveness of Complex I and Its Potential Evolutionary Scheme Abstract. Most cellular reactions are interdependent; however, a subset of reactions often associate more closely to form a defined reaction pathway. An ex

A. Shirsath, @amiteshanand.bsky.social et al. analyzed the prokaryotic genome space to trace the distribution of 14 core C-I or NADH-quinone oxidoreductase subunits. Authors share these results on prokcomplexone.streamlit.app

🔗 doi.org/10.1093/gbe/...

#genome #evolution #microbesky

🚨Spoiler alert

✅Only microbes can metabolize sulfoquinovose (SQ) - not the host

✅Specialized SQ fermenting bacteria in the gut not only produce acetate but also butyrate

✅A standard lab mouse is not an ideal model to study health impacts of SQ metabolism in humans

🦠🧫 #microbesky #microbiomesky

Sulfoquinovose is exclusively metabolized by the gut microbiota and degraded differently in mice and humans - Microbiome Background Sulfoquinovose (SQ) is a green-diet-derived sulfonated glucose and a selective substrate for a limited number of human gut bacteria. Complete anaerobic SQ degradation via interspecies metab...

Our recent paper by @julkras.bsky.social provides further insights into the metabolism of sulfoquinovose in humans and lab mice, and its prebiotic potential.

🦠🧫 #microbesky #microbiomesky

microbiomejournal.biomedcentral.com/articles/10....